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List of works by Traver Hart

A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality.

scientific article

A network of human functional gene interactions from knockout fitness screens in cancer cells

article

All for One, and One for All.

scientific article

Application of microdroplet PCR for large-scale targeted bisulfite sequencing.

scientific article

BAGEL: a computational framework for identifying essential genes from pooled library screens.

scientific article

Common computational tools for analyzing CRISPR screens

publication published on 01 December 2021

DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress

scientific article published on 21 December 2020

Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation

scientific article

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

scientific article

Extensive mapping of an innate immune network with CRISPR.

scientific article published on 24 July 2015

Finding the active genes in deep RNA-seq gene expression studies

scientific article

Genetic vulnerabilities upon inhibition of DNA damage response

scientific article published on 01 August 2021

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

scientific article published on 21 November 2016

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

scientific article

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.

scientific article

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

scientific article published on 25 November 2015

High-Throughput Immunofluorescence Microscopy Using Yeast Spheroplast Cell-Based Microarrays ⬇️

scientific article published on January 1, 2011

How complete are current yeast and human protein-interaction networks?

scientific article published on January 2006

Human cell chips: adapting DNA microarray spotting technology to cell-based imaging assays

scientific article

HumanNet v3: an improved database of human gene networks for disease research

scientific article published on 19 October 2021

Identifying chemogenetic interactions from CRISPR screens with drugZ

scientific article published on 22 August 2019

Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier

scientific article published on 06 January 2021

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

scientific article

Method for improved Illumina sequencing library preparation using NuGEN Ovation RNA-Seq System.

scientific article

MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes

scientific article

Microdroplet PCR for Highly Multiplexed Targeted Bisulfite Sequencing

scientific article published in January 2018

Multiplex enCas12a screens detect functional buffering among paralogs otherwise masked in monogenic Cas9 knockout screens

scientific article published on 15 October 2020

Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes

article

PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens.

scientific article

Scaling up the systematic hunt for mammalian genetic interactions

scientific article published on 01 May 2013

Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast.

scientific article published in January 2009

Systematic discovery and classification of human cell line essential genes

article

Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes

scientific article

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