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List of works by Rosa Molfetta

3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

scientific article

Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia

scientific article published on 14 August 2018

Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.

scientific article published on 26 July 2002

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms

scientific article published on 24 May 2019

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

scientific article published on 13 February 2020

CD155: A Multi-Functional Molecule in Tumor Progression

scientific article published on 30 January 2020

CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function

scientific article published on October 2005

Cbl family proteins: balancing FcεRI-mediated mast cell and basophil activation

scientific article published on 29 March 2011

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes

scientific article published on 30 July 2020

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

scientific article published on 12 June 2015

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

scientific article published on 13 January 2017

Immune complexes exposed on mast cell-derived nanovesicles amplify allergic inflammation

scientific article published on 12 November 2019

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

scientific article published on December 2016

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

scientific article

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors

scientific article

NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction

scientific article (publication date: 2 January 2002)

NK cells and interferons.

scientific article

NKG2D and Its Ligands: "One for All, All for One".

scientific article

Negative signals from FcepsilonRI engagement attenuate mast cell functions.

scientific article published on 23 July 2007

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

scientific article published on 22 January 2015

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production

scientific article published on 10 February 2017

PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway

scientific article published on 23 January 2012

Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention

scientific article published on 31 October 2019

Regulation of NKG2D Expression and Signaling by Endocytosis

scientific article published on 22 September 2016

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis

scientific article published on 2 August 2017

Regulation of fc receptor endocytic trafficking by ubiquitination.

scientific article published on 18 September 2014

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

scientific article published on 28 September 2020

Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: impact on Hrs membrane/cytosol localization

scientific journal article

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

scientific article

The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing

scientific article published on 27 March 2019

The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway

scientific journal article

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors

scientific article published on 11 April 2019

Translating the anti-myeloma activity of Natural Killer cells into clinical application

scientific article published on 10 October 2018

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

scientific article published on 27 October 2015

Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.

scientific article

c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.

scientific article

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

scientific article published on 2 December 2016

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