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List of works by James G Kench

5-Alpha reductase inhibitors and PSA screening for prostate cancer

A prospective multicentre phase III validation study of AZGP1 as a biomarker in localized prostate cancer.

scientific article published on 9 May 2017

A qualitative study of the development of a multidisciplinary case conference review methodology to reduce involved margins in pelvic exenteration surgery for recurrent rectal cancer

scientific article published on 16 July 2018

A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes.

scientific article published on 17 August 2009

Abdominal actinomycosis presenting as appendicitis: two case reports and review.

scientific article published on 3 May 2016

Aberrant Neuropeptide Y and Macrophage Inhibitory Cytokine-1 Expression Are Early Events in Prostate Cancer Development and Are Associated with Poor Prognosis

article

Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma.

scientific article published on June 2002

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.

scientific article published on 7 November 2017

Adenocarcinoma arising within ectopic prostatic tissue in the urinary bladder

scientific article published on 01 December 2014

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

scientific article

Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer.

scientific article

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

scientific article published on 04 December 2018

Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation.

scientific article published on December 2014

Beyond insulin resistance in NASH: TNF-alpha or adiponectin?

scientific article published in July 2004

Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature.

scientific article

Breast carcinoma in a fibroadenoma: diagnosis by fine needle aspiration cytology

scientific article published on 01 November 1998

Cancer stem cell markers in prostate cancer: an immunohistochemical study of ALDH1, SOX2 and EZH2.

scientific article

Classification, morphology and molecular pathology of premalignant lesions of the pancreas.

scientific article published on April 2013

Clinical and immunohistochemical features of 34 solid pseudopapillary tumors of the pancreas.

scientific article published in February 2011

Clinical and pathologic features of familial pancreatic cancer

scientific article published on 14 October 2014

Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.

scientific article

Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies

scientific article published on July 2010

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours

scientific article published on 27 September 2017

Cyclin E Expression and Outcome in Pancreatic Ductal Adenocarcinoma

scientific article published on 01 October 2006

DPC4/Smad4 Expression and Outcome in Pancreatic Ductal Adenocarcinoma

article

Dataset for reporting of prostate carcinoma in radical prostatectomy specimens: recommendations from the International Collaboration on Cancer Reporting.

scientific article published on January 2013

Dataset for the reporting of prostate carcinoma in radical prostatectomy specimens: updated recommendations from the International Collaboration on Cancer Reporting

scientific article published on 16 May 2019

ERG induces taxane resistance in castration-resistant prostate cancer

scientific article

Early diagnosis and resection of an asymptomatic leiomyosarcoma of the inferior vena cava prior to caval obstruction.

scientific article published on 5 October 2011

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

scientific article

Enduring epigenetic landmarks define the cancer microenvironment

scientific article published on 12 April 2018

Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers.

scientific article

Expression of E6AP and PML predicts for prostate cancer progression and cancer-specific death

scientific article published on 17 September 2014

Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia

scientific article

Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer

scientific article published on 16 April 2009

Expression of phosphorylated-mTOR during the development of prostate cancer.

scientific article published on 07 July 2014

Expression of the zinc transporter ZnT4 is decreased in the progression from early prostate disease to invasive prostate cancer.

scientific article

Extraprostatic extension (EPE) of prostatic carcinoma: is its proximity to the surgical margin or Gleason score important?

scientific article published on 19 August 2014

Gene based prediction of clinically localized prostate cancer progression after radical prostatectomy.

scientific article

General parity between trio and pairwise breeding of laboratory mice in static caging

scientific article published on November 2014

Genomic analyses identify molecular subtypes of pancreatic cancer

scientific article published on 24 February 2016

Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C.

scientific article published in September 2008

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

scientific article

Grade of deceased donor liver macrovesicular steatosis impacts graft and recipient outcomes more than the Donor Risk Index.

scientific article published on March 2012

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

scientific article

HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer

scientific article published on 28 November 2008

Hepatobiliary and Pancreatic: Kasabach-Merritt syndrome in adult

scientific article published on 28 May 2019

High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy.

scientific article published on 12 October 2011

High sensitivity C-reactive protein values do not reliably predict the severity of histological changes in NAFLD.

scientific article

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

scientific article published on 25 February 2013

Histopathology of pembrolizumab-induced hepatitis: a case report.

scientific article published on 24 October 2017

Hypermutation In Pancreatic Cancer

scientific article

INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival.

scientific article published on 4 October 2014

Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse.

scientific article

Individualizing therapy for pancreatic cancer

scientific article published on 01 December 2008

Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.

scientific article published in October 2007

International Society of Urological Pathology (ISUP) Grading of Prostate Cancer

scientific article published on 28 March 2016

International network of cancer genome projects

scientific article

Intraductal papillary-mucinous neoplasm of the pancreas: a report of five cases with immunohistochemical findings

scientific article published on 01 February 1997

Intraductal tubulopapillary neoplasm of pancreas with associated invasive carcinoma, lymph node, rectal and hepatic metastases.

scientific article published in February 2015

Ipilimumab-induced toxicities and the gastroenterologist.

scientific article

LMO4 expression in squamous cell carcinoma of the anterior tongue.

scientific article

Leptomeningeal carcinomatosis from squamous cell carcinoma of the supraglottic larynx

scientific article

Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C.

scientific article published in August 2003

Loss of AZGP1 as a Superior Predictor of Relapse in Margin-Positive Localized Prostate Cancer

scientific article published on 30 July 2016

Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression.

scientific article published in May 2004

Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions.

scientific article published on 24 July 2006

Low AZGP1 expression predicts for recurrence in margin-positive, localized prostate cancer

scientific article published on 22 March 2011

Lower levels of nuclear beta-catenin predict for a poorer prognosis in localized prostate cancer.

scientific article

Margin clearance and outcome in resected pancreatic cancer

scientific article

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

scientific article

Messina: a novel analysis tool to identify biologically relevant molecules in disease.

scientific article

Meta-analysis of radical resection rates and margin assessment in pancreatic cancer

scientific article published on 09 September 2015

Molecular pathogenesis of precursor lesions of pancreatic ductal adenocarcinoma ⬇️

scientific article published on February 1, 2003

Monitoring quality of care for patients with pancreatic cancer: a modified Delphi consensus

scientific article published on 11 October 2018

Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma.

scientific article published on 6 July 2018

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

scientific article published on 05 October 2016

Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue.

scientific article published on September 2003

Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.

scientific article

Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer.

scientific article published on July 2004

Oxidative stress is closely associated with insulin resistance in genotypes 1 and 3 chronic hepatitis C.

scientific article published on 27 September 2012

Pancreatic Intraepithelial Neoplasia in Association With Intraductal Papillary Mucinous Neoplasms of the Pancreas

article

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Pathology Imagebase-a reference image database for standardization of pathology.

scientific article

Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma.

scientific article published on April 2013

Phosphorylated Akt expression is a prognostic marker in early-stage non-small cell lung cancer

scientific article published on 21 November 2013

Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.

scientific article

Precursor lesions in pancreatic cancer: morphological and molecular pathology.

scientific article published on April 2011

Predictive value of the 2014 International Society of Urological Pathology grading system for prostate cancer in patients undergoing radical prostatectomy with long-term follow-up

scientific article

Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens.

scientific article published on August 2011

Prostate Cancer Grading, Time To Go Back To the Future

scientific article published on 18 November 2020

Prostate Cancer Grading: A Decade After the 2005 Modified Gleason Grading System

scientific article published on 01 February 2017

Prostate specific antigen testing: age-related interpretation in early prostate cancer detection.

scientific article published in June 2013

Real time intraoperative confocal laser microscopy-guided surgery

scientific article

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction

scientific article

Refining the care of patients with pancreatic cancer: the AGITG Pancreatic Cancer Workshop consensus.

scientific article published on June 2016

Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.

scientific article published on 5 September 2013

Reticular and microcystic schwannoma of the parotid gland

scientific article published on 01 January 2013

Retinoid signaling in pancreatic cancer, injury and regeneration.

scientific article

Retroperitoneal inflammatory liposarcoma in a patient with non-hodgkin lymphoma: a report highlighting diagnostic pitfalls.

scientific article

Sarcomatoid carcinoma of the ampulla of Vater

scientific article published on 01 February 1997

Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer

scientific article

Stabilization of beta-catenin induces pancreas tumor formation

scientific article published on 09 July 2008

Surveillance after prostate focal therapy

scientific article published on 09 June 2018

Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse.

scientific article

Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma

scientific article published on 18 August 2018

Synoptic reporting improves histopathological assessment of pancreatic resection specimens

scientific article

TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.

scientific article published on 31 July 2009

The dilemmas of prostate cancer screening

The effects of non-steroidal inhibitors of phospholipase A2 on leukotriene and histamine release from human and guinea-pig lung.

scientific article published on August 1985

The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome

scientific article

Utility of Pathology Imagebase for Standardization of Prostate Cancer Grading

scientific article published on 23 January 2018

Visceral fat: a key mediator of steatohepatitis in metabolic liver disease.

scientific article

Washout of hepatocellular carcinoma on portal venous phase of multidetector computed tomography in a pre-transplant population.

scientific article published on 4 August 2015

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

Whole-genome landscape of pancreatic neuroendocrine tumours.

scientific article published on 15 February 2017

Zinc-alpha2-glycoprotein Expression as a Predictor of Metastatic Prostate Cancer Following Radical Prostatectomy

article

p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue

scientific article published on 01 June 2005

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