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List of works by Atsushi Harada

Acceleration of enzymatic reaction of trypsin through the formation of water-soluble complexes with poly(ethylene glycol)-block-poly(alpha,beta-aspartic acid).

scientific article

Aqueous solubilization of fullerenes using poly(amidoamine) dendrimers bearing cyclodextrin and poly(ethylene glycol).

scientific article

Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy

scientific article published on 15 January 2018

Carboxylated phytosterol derivative-introduced liposomes for skin environment-responsive transdermal drug delivery system.

scientific article

Cationic polymers with inhibition ability of DNA condensation elevate gene expression

scientific article published on 01 September 2010

Chondroitin Sulfate-Based pH-Sensitive Polymer-Modified Liposomes for Intracellular Antigen Delivery and Induction of Cancer Immunity

scientific article published on 11 April 2019

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change ⬇️

scientific article published on October 6, 2003

Development of pH-Responsive Hyaluronic Acid-Based Antigen Carriers for Induction of Antigen-Specific Cellular Immune Responses

scientific article published on 25 October 2019

Development of pH-sensitive Dextran Derivatives with Strong Adjuvant Function and Their Application to Antigen Delivery

scientific article published on 4 August 2017

Doxorubicin Delivery Using pH and Redox Dual-Responsive Hollow Nanocapsules with a Cationic Electrostatic Barrier

scientific article published on 30 December 2016

Effect of enzyme modification by well-defined multi-armed poly(ethylene glycol) synthesized using polyamidoamine dendron

scientific article published on 30 August 2010

Effect of head size in head-tail-type polycations on their in vitro performances as nonviral gene vectors.

scientific article published in June 2009

Effect of transferrin as a ligand of pH-sensitive fusogenic liposome-lipoplex hybrid complexes.

scientific article

Effect of unsaturated alkyl chains on transfection activity of poly(amidoamine) dendron-bearing lipids ⬇️

scientific article published on April 10, 2012

Effective Condensation of Multivalent Anions into Polyion Complex Micelles Prepared from TiO₂ Nanoparticles and Polyallylamine Bearing Poly(ethylene glycol) Grafts.

scientific article published on 17 July 2015

Effective accumulation of polyion complex micelle to experimental choroidal neovascularization in rats

scientific article published on 01 January 2004

Effective tolerance to serum proteins of head-tail type polycation vectors by PEGylation at the periphery of the head block

scientific article published on 01 April 2010

Emerging paradigms in nanotechnology for imaging and treatment of cerebral ischemia

scientific article published on 22 February 2019

Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions

scientific article published on July 2002

Gene Expression of Aspect Ratio-Controlled Polyplexes Based on the Effect of Multi-Arm Poly(ethylene glycol)

scientific article published on 29 March 2019

Gene expression of ternary complexes through the compaction of nanofiber-polyplexes by mixing with lipofectamine.

scientific article published on 2 April 2015

Glutathione-Sensitive Stabilization of Block Copolymer Micelles Composed of Antisense DNA and Thiolated Poly(ethylene glycol)-block-poly(l-lysine): A Potential Carrier for Systemic Delivery of Antisense DNA ⬇️

scientific article published on January 1, 2001

Highly Ordered Polypeptide with UCST Phase Separation Behavior

scientific article published on 11 January 2019

Hyaluronic Acid-Based pH-Sensitive Polymer-Modified Liposomes for Cell-Specific Intracellular Drug Delivery Systems

scientific article published on 28 November 2017

Improvement of Peptide-Based Tumor Immunotherapy Using pH-Sensitive Fusogenic Polymer-Modified Liposomes.

scientific article published on 26 September 2016

In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine

scientific article

Intracellular environment-responsive stabilization of polymer vesicles formed from head-tail type polycations composed of a polyamidoamine dendron and poly(L-lysine).

scientific article

Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy

scientific article published on 19 November 2010

Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy.

scientific article published on 8 August 2015

PEGylated PAMAM dendrimer-doxorubicin conjugate-hybridized gold nanorod for combined photothermal-chemotherapy

scientific article

Polyamidoamine Dendron-Bearing Lipids as a Nonviral Vector: Influence of Dendron Generation ⬇️

scientific article published on March 16, 2012

Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer.

scientific article published on December 2003

Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy.

scientific article

Preparation of dual-stimuli-responsive liposomes using methacrylate-based copolymers with pH and temperature sensitivities for precisely controlled release

scientific article published on 23 April 2017

Preparation of poly(ethylene glycol)-modified poly(amido amine) dendrimers encapsulating gold nanoparticles and their heat-generating ability.

scientific article published on 10 April 2007

Pronounced activity of enzymes through the incorporation into the core of polyion complex micelles made from charged block copolymers.

scientific article published in May 2001

Rendering poly(amidoamine) or poly(propylenimine) dendrimers temperature sensitive.

scientific article

Soft Matter-Regulated Active Nanovalves Locally Self-Assembled in Femtoliter Nanofluidic Channels

scientific article published on 20 January 2016

Sonodynamic Therapeutic Effects of Sonosensitizers with Different Intracellular Distribution Delivered by Hollow Nanocapsules Exhibiting Cytosol Specific Release

scientific article published on 01 February 2019

Stabilization of lysozyme-incorporated polyion complex micelles by the omega-end derivatization of poly(ethylene glycol)-poly(alpha,beta-aspartic acid) block copolymers with hydrophobic groups.

scientific article

Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules.

scientific article published in January 2001

Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate.

scientific article published on September 2005

Synthesis and characterization of a head-tail type polycation block copolymer as a nonviral gene vector.

scientific article published in January 2006

Synthesis and characterization of hyperbranched poly(glycidol) modified with pH- and temperature-sensitive groups.

scientific article published in May 2009

Synthesis of oligo(ethylene glycol)-modified hyperbranched poly(glycidol)s for dual sensitization of liposomes to pH and temperature

Synthesis, Characterization, and Biomedical Applications of an Alkylated Quercetin-Gadolinium Complex

scientific article published on 14 February 2019

Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu.

scientific article

The application of pH-sensitive polymer-lipids to antigen delivery for cancer immunotherapy ⬇️

scientific article published on April 29, 2013

Thermosensitive properties of poly(amidoamine) dendrimers with peripheral phenylalanine residues.

scientific article

X-ray computed tomography contrast agents prepared by seeded growth of gold nanoparticles in PEGylated dendrimer.

scientific article published on 25 May 2010

pH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-γ gene lipoplex for efficient cancer immunotherapy.

scientific article published on 17 July 2015

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