List of works - Gábor Pál

A redesigned genetic code for selective labeling in protein NMR

scientific article published on 01 August 2008

Alteration of the specificity of ecotin, an E. coli serine proteinase inhibitor, by site directed mutagenesis.

scientific article

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

scientific article published on 16 May 2016

Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning

scientific article

Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation.

scientific article published on 23 February 2018

DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond.

scientific article published on 08 August 2011

Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.

scientific article

Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

scientific article

Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model

scientific article published on 11 December 2018

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum

scientific article published on 20 December 2019

Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones.

scientific article

High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues

scientific article

Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.

scientific article published on 17 December 2001

In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership

scientific article

Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis

scientific article published on 01 April 2005

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model.

scientific article

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

scientific article published on 18 August 2016

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

scientific article

Mutant rat trypsin selectively cleaves tyrosyl peptide bonds.

scientific article published in March 2004

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

scientific article published on 05 April 2019

Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway.

scientific article

Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes

scientific article

Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P(1) and P(1)' residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor.

scientific article published on September 1999

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway

scientific article

Reexamination of the recognition preference of the specificity pocket of the Abl SH3 domain

scientific article

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

scientific article

Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation

scientific article

Specificity assay of serine proteinases by reverse-phase high-performance liquid chromatography analysis of competing oligopeptide substrate library.

scientific article

Structural determinants governing S100A4-induced isoform-selective disassembly of nonmuscle myosin II filaments.

scientific article

The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action

scientific article

The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.

scientific article

The first semi-synthetic serine protease made by native chemical ligation.

scientific article published in June 2003

Two mutations in rat trypsin confer resistance against autolysis.

scientific article

When the surface tells what lies beneath: combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family.

scientific article

List of works by Gábor Pál

A redesigned genetic code for selective labeling in protein NMR

Alteration of the specificity of ecotin, an E. coli serine proteinase inhibitor, by site directed mutagenesis.

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning

Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation.

DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond.

Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.

Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum

Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones.

High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues

Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.

In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership

Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model.

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

Mutant rat trypsin selectively cleaves tyrosyl peptide bonds.

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway.

Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes

Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P(1) and P(1)' residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor.

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway

Reexamination of the recognition preference of the specificity pocket of the Abl SH3 domain

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation

Specificity assay of serine proteinases by reverse-phase high-performance liquid chromatography analysis of competing oligopeptide substrate library.

Structural determinants governing S100A4-induced isoform-selective disassembly of nonmuscle myosin II filaments.

The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action

The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.

The first semi-synthetic serine protease made by native chemical ligation.

Two mutations in rat trypsin confer resistance against autolysis.

When the surface tells what lies beneath: combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family.