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List of works by Anthony M Joshua

18F-FDG-PET/CT in the Staging and Management of Melanoma: A Prospective Multicenter Ontario PET Registry Study.

scientific article published on 8 October 2015

A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205

scientific article published on 15 March 2019

A phase 2 study of tremelimumab in patients with advanced uveal melanoma

scientific article published on August 2015

A phase 2 trial of sunitinib in patients with progressive paraganglioma or pheochromocytoma: the SNIPP trial

scientific article published on 20 May 2019

A phase II study of GW786034 (pazopanib) with or without bicalutamide in patients with castration-resistant prostate cancer

scientific article published on 8 June 2014

A pilot 'window of opportunity' neoadjuvant study of metformin in localised prostate cancer.

scientific article published on 27 May 2014

A prognostic index model for predicting overall survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate after docetaxel.

scientific article

A prospective study examining elder-relevant outcomes in older adults with prostate cancer undergoing treatment with chemotherapy or abiraterone

scientific article published on 4 February 2016

A randomized phase 2 study of a HSP27 targeting antisense, apatorsen with prednisone versus prednisone alone, in patients with metastatic castration resistant prostate cancer

scientific article published on 18 December 2017

A randomized phase II trial of geriatric assessment and management for older cancer patients.

scientific article published on 25 July 2017

A retrospective, Canadian multi-center study examining the impact of prior response to abiraterone acetate on efficacy of docetaxel in metastatic castration-resistant prostate cancer

scientific article published on 29 August 2014

AR Signaling and the PI3K Pathway in Prostate Cancer

scientific article published on 15 April 2017

AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate.

scientific article published on 17 July 2016

Abiraterone acetate in metastatic castration-resistant prostate cancer: a retrospective review of the Princess Margaret experience of (I) low dose abiraterone and (II) prior ketoconazole

scientific article published on 16 July 2014

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

scientific article published on 23 May 2008

Advanced Adrenocortical Carcinoma (ACC): a Review with Focus on Second-Line Therapies

scientific article published on 17 April 2020

Anti-PD-1/PD-L1 immunotherapy in patients with solid organ transplant, HIV or hepatitis B/C infection

article

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial

scientific article (publication date: 20 September 2014)

Assessment of a prognostic model, PSA metrics and toxicities in metastatic castrate resistant prostate cancer using data from Project Data Sphere (PDS)

scientific article (publication date: 2017)

Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

scientific article published on April 2016

Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab

article

Beyond castration-defining future directions in the hormonal treatment of prostate cancer

scientific article published on April 2012

Burden of illness for metastatic melanoma in Canada, 2011-2013

scientific article

Carney complex with adrenal cortical carcinoma

scientific article

Cell-free DNA modification dynamics in abiraterone acetate-treated prostate cancer patients.

scientific article published on 3 April 2018

Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial

scientific article published on 13 January 2016

Chemotherapy treatment decision-making experiences of older adults with cancer, their family members, oncologists and family physicians: a mixed methods study

scientific article published on 9 November 2016

Choosing a better end point for trials of bone-protective agents.

scientific article

Clinical Outcomes of First-line Abiraterone Acetate or Enzalutamide for Metastatic Castration-resistant Prostate Cancer After Androgen Deprivation Therapy + Docetaxel or ADT Alone for Metastatic Hormone-sensitive Prostate Cancer

scientific article published on 27 December 2017

Clinical variables associated with PSA response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer.

scientific article published on 23 January 2014

Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials

scientific article published on 07 December 2018

Development of an adoptive cell therapy protocol with tumor-infiltrating lymphocytes and intermediate-dose interleukin-2 therapy

scientific article published on 7 November 2013

Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma

scientific article published on 28 December 2017

Duration of suppression of bone turnover following treatment with zoledronic acid in men with metastatic castration-resistant prostate cancer

scientific article published on 20 October 2017

Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

scientific article published on 3 February 2015

Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial

scientific article published on 18 June 2014

Efficacy and toxicity of abiraterone and docetaxel in octogenarians with metastatic castration-resistant prostate cancer

scientific article published on 7 October 2014

Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies

scientific article published in 2021

Enzalutamide in metastatic prostate cancer before chemotherapy

scientific article published in June 2014

Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer

scientific article published on 02 June 2019

Eosinophilic Fasciitis and Acute Encephalopathy Toxicity from Pembrolizumab Treatment of a Patient with Metastatic Melanoma

scientific article published on 28 January 2016

Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab

scientific article published on 07 March 2016

Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs)

scientific article published on 10 November 2010

Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer

scientific article published on 01 November 2020

Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001

scientific article published on 01 April 2019

Health status, emergency department visits, and oncologists' feedback: An analysis of secondary endpoints from a randomized phase II geriatric assessment trial

scientific article published in January 2019

Hyperprogressive disease in early-phase immunotherapy trials: Clinical predictors and association with immune-related toxicities

scientific article published on 15 February 2019

Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate

scientific article published on 15 January 2015

Increased treatment-related toxicity subsequent to an anti-PD-1 agent

scientific article published on August 2015

Influence of concurrent medications on outcomes of men with prostate cancer included in the TAX 327 study

scientific article published on January 2013

Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias

scientific article published on September 2006

LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.

scientific article

Malignant pheochromocytoma secreting vasoactive intestinal peptide and response to sunitinib: a case report and literature review

scientific article

Management of carcinoma of the penis: Consensus statement from the Canadian Association of Genitourinary Medical Oncologists (CAGMO).

scientific article published in November 2013

Melanoma prevention: are we doing enough? A Canadian perspective.

scientific article

Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study

scientific article published on 01 August 2019

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

scientific article published on 25 October 2016

Neoadjuvant Enzalutamide Prior to Prostatectomy

scientific article published on 9 November 2016

Neutrophil-Lymphocyte Ratio and Pathological Response to Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer

scientific article published on 07 February 2015

New treatments for metastatic melanoma ⬇️

scientific article

Oncogenic signaling in uveal melanoma.

scientific article published on 8 May 2018

Oncology in 2050 - A Retrospective?

scientific article published on 25 April 2020

Outcomes of universal germline testing for men with prostate cancer in an Australian tertiary center

scientific article published on 22 April 2019

Outcomes with Abiraterone Acetate in Metastatic Castration-resistant Prostate Cancer Patients Who Have Poor Performance Status

scientific article published in March 2015

PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy

scientific article published on 23 November 2011

PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade

scientific article published on 28 September 2012

Pantoprazole Affecting Docetaxel Resistance Pathways via Autophagy (PANDORA): Phase II Trial of High Dose Pantoprazole (Autophagy Inhibitor) with Docetaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

scientific article published on 05 April 2019

Patterns of response in patients with advanced melanoma treated with Pembrolizumab (MK-3475) and evaluation of immune-related response criteria (irRC).

scientific article published on 6 November 2014

Patterns of response to anti-PD-1 treatment: an exploratory comparison of four radiological response criteria and associations with overall survival in metastatic melanoma patients

scientific article published on 4 October 2016

Pembrolizumab

scientific article (publication date: 2015)

Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2

scientific article published on 11 February 2019

Phase II study of cytarabine in men with docetaxel-refractory, castration-resistant prostate cancer with evaluation of TMPRSS2-ERG and SPINK1 as serum biomarkers

scientific article published on 07 February 2012

Phase II study of preoperative gefitinib in clinical stage I non-small-cell lung cancer

scientific article published on 2 November 2009

Prognostic factors for first-line therapy and overall survival of metastatic uveal melanoma

scientific article published on 01 December 2018

Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma

scientific article published on 31 October 2016

Prostate cancer as a model system for genetic diversity in tumors

scientific article published on January 2011

Purchasing silence

scientific article published on 10 April 2018

Radiation recall dermatitis triggered by multi-targeted tyrosine kinase inhibitors: sunitinib and sorafenib

scientific article published in February 2010

Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma

scientific article

Real-world efficacy, toxicity and clinical management of ipilimumab treatment in metastatic melanoma.

scientific article published on 31 December 2015

Refining the Assessment and Implications of AR-V7 in Castrate-resistant Prostate Cancer

scientific article published on 18 November 2017

Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma

scientific article published on 05 December 2016

Renal cell carcinoma bone metastases: clinical advances

scientific article published in March 2010

Resource utilization and costs of managing patients with advanced melanoma: a Canadian population-based study

scientific article

Results of a Prospective Phase 2 Pilot Trial of 177Lu–PSMA-617 Therapy for Metastatic Castration-Resistant Prostate Cancer Including Imaging Predictors of Treatment Response and Patterns of Progression

scientific article published in February 2019

Retinal vasculitis and ocular vitreous metastasis following complete response to PD-1 inhibition in a patient with metastatic cutaneous melanoma

scientific article published on 16 December 2014

Retreatment of men with metastatic castrate-resistant prostate cancer with abiraterone

scientific article published on 11 August 2014

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

scientific article (publication date: 11 July 2013)

Safety of enzalutamide in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel: expanded access in North America

scientific article published on 14 February 2015

Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT).

scientific article published on 12 March 2018

Study of testosterone-guided androgen deprivation therapy in management of prostate cancer

scientific article published on 2 November 2015

TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair

scientific article published on 5 August 2013

Targeting the androgen receptor in the management of castration-resistant prostate cancer: rationale, progress, and future directions

scientific article

The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis

scientific article published on 07 May 2020

The Utility of Serum CA9 for Prognostication in Prostate Cancer

scientific article published on September 2016

The changing landscape in metastatic castration-resistant prostate cancer

scientific article published on September 2013

The full blood count as a biomarker of outcome and toxicity in ipilimumab-treated cutaneous metastatic melanoma

scientific article published on 29 September 2016

Therapeutic implications of germline genetic findings in cancer

scientific article published on 01 June 2019

Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies.

scientific article published on 28 October 2010

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

scientific article

Translating clinical trials to clinical practice: outcomes of men with metastatic castration resistant prostate cancer treated with docetaxel and prednisone in and out of clinical trials.

scientific article published on 14 October 2013

Treatment Outcomes from 68Ga-PSMA PET/CT-Informed Salvage Radiation Treatment in Men with Rising PSA After Radical Prostatectomy: Prognostic Value of a Negative PSMA PET.

scientific article published on 26 July 2017

Treatment of mCRPC in the AR-axis-targeted therapy-resistant state

scientific article published on 22 June 2015

Understanding how prostate cancer patients value the current treatment options for metastatic castration resistant prostate cancer

scientific article published on 14 February 2018

Understanding the role of new systemic agents in the treatment of prostate cancer.

scientific article published on 6 October 2016

Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.

scientific article

Use of a clinical assistant to screen patients with genitourinary cancer to encourage entry into clinical trials and use of supportive medication: a pilot project at a Canadian cancer center

scientific article published on 9 May 2013

Web-based resources for clinical bioinformatics.

scientific article published on January 2008

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