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List of works by Tanya Applegate

96 shRNAs designed for maximal coverage of HIV-1 variants

scientific article published on 04 June 2009

A comparison of seminal hepatitis C virus (HCV) RNA levels during recent and chronic HCV infection in HIV-infected and HIV-uninfected individuals

scientific article

A molecular transmission network of recent hepatitis C infection in people with and without HIV: Implications for targeted treatment strategies

scientific article published on 24 November 2016

A quantitative comparison of anti-HIV gene therapy delivered to hematopoietic stem cells versus CD4+ T cells

scientific article

Adherence to response-guided pegylated interferon and ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: the ACTIVATE study

scientific article

Alanine aminotransferase, HCV RNA levels and pro-inflammatory and pro-fibrogenic cytokines/chemokines during acute hepatitis C virus infection

scientific article published on 24 February 2016

An infinitely expandable cloning strategy plus repeat-proof PCR for working with multiple shRNA.

scientific article

Analysis of resistance-associated substitutions in acute hepatitis C virus infection by deep sequencing across six genotypes and three continents.

scientific article

Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success

scientific article published on 30 October 2009

Drug use and phylogenetic clustering of hepatitis C virus infection among people who use drugs in Vancouver, Canada: A latent class analysis approach

scientific article

Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment.

scientific article published on 31 January 2017

Dynamics of HCV RNA levels during acute hepatitis C virus infection

scientific article

Efficacy of response-guided directly observed pegylated interferon and self-administered ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study

scientific article published on 14 June 2017

Elbasvir and grazoprevir for hepatitis C virus genotype 1 infection in people with recent injecting drug use (DARLO-C): An open-label, single-arm, phase 4, multicentre trial

scientific article published on 15 March 2020

Evaluation of a Hepatitis C Virus Core Antigen Assay in Plasma and Dried Blood Spot Samples

scientific article published on 26 June 2018

Evaluation of a hepatitis C virus core antigen assay from venepuncture and dried blood spot collected samples: A cohort study

scientific article published on 18 September 2019

Evaluation of the Xpert HCV Viral Load point-of-care assay from venepuncture-collected and finger-stick capillary whole-blood samples: a cohort study

scientific article published on 21 April 2017

Evaluation of the Xpert® HCV Viral Load Fingerstick point-of-care assay

scientific article published on 9 March 2018

Factors associated with hepatitis C virus RNA levels in early chronic infection: the InC3 study

scientific article published on 8 January 2015

Factors that influence deoxyribozyme cleavage during polymerase chain reaction

scientific article published on 01 November 2000

HCV avidity as a tool for detection of recent HCV infection: sensitivity depends on HCV genotype

scientific article

HCV reinfection incidence among individuals treated for recent infection.

scientific article

HIV infection and hepatitis C virus genotype 1a are associated with phylogenetic clustering among people with recently acquired hepatitis C virus infection.

scientific article published on 26 November 2015

HIV infection is associated with higher levels of monocyte chemoattractant protein-1 and eotaxin among people with recent hepatitis C virus infection

scientific article

Hepatitis C Virus Diagnosis and the Holy Grail

scientific article published on 01 June 2018

Hepatitis C point-of-care diagnostics: in search of a single visit diagnosis

scientific article

Hepatitis C virus core antigen: A simplified treatment monitoring tool, including for post-treatment relapse

scientific article published on 11 May 2017

Historical Trends in the Hepatitis C Virus Epidemics in North America and Australia

scientific article published on 28 August 2016

In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy

scientific article

Interferon lambda 3 genotype predicts hepatitis C virus RNA levels in early acute infection among people who inject drugs: the InC(3) study

scientific article

Interferon λ 3 and 4 Genotyping Using High-Resolution Melt Curve Analysis Suitable for Multiple Clinical Sample Types.

scientific article

Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection

scientific article published on 5 January 2017

Maximum levels of hepatitis C virus lipoviral particles are associated with early and persistent infection

scientific article published on 25 May 2016

Metabolism of ethanol by rat pancreatic acinar cells

scientific article published on 01 October 1998

Methamphetamine injecting is associated with phylogenetic clustering of hepatitis C virus infection among street-involved youth in Vancouver, Canada

scientific article published on 20 April 2015

Mixed HCV infection and reinfection in people who inject drugs--impact on therapy

scientific article published on 17 March 2015

Multiple shRNA combinations for near-complete coverage of all HIV-1 strains

scientific article

Naturally occurring dominant drug resistance mutations occur infrequently in the setting of recently acquired hepatitis C.

scientific article

Non-oxidative metabolism of ethanol by rat pancreatic acini.

scientific article published on 30 March 2004

Patterns of hepatitis C virus RNA levels during acute infection: the InC3 study

scientific article

Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.

scientific article

Phylogenetic analysis of full-length, early infection, hepatitis C virus genomes among people with intravenous drug use: the InC3 Study.

scientific article

Phylogenetic clustering of hepatitis C virus among people who inject drugs in Vancouver, Canada

scientific article

Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection.

scientific article published on 8 May 2013

Plasma interferon-gamma-inducible protein-10 levels are associated with early, but not sustained virological response during treatment of acute or early chronic HCV infection

scientific article

Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection

scientific article

Sequencing of the Hepatitis C Virus: A Systematic Review.

scientific article

Short duration response-guided treatment is effective for most individuals with recent hepatitis C infection: the ATAHC II and DARE-C I studies

scientific article published on 11 February 2016

Short duration response-guided treatment is effective for most individuals with recent hepatitis C infection: the ATAHC II and DARE-C I studies.

scientific article published on 10 August 2016

Shortened therapy of eight weeks with paritaprevir/ritonavir/ombitasvir and dasabuvir is highly effective in people with recent HCV genotype 1 infection.

scientific article published on 16 April 2018

Sofosbuvir and ribavirin for 6 weeks is not effective among people with recent hepatitis C virus infection: The DARE-C II study

scientific article

Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial

scientific article published on 5 January 2018

The Influence of Hepatitis C Virus Genetic Region on Phylogenetic Clustering Analysis

scientific article published on 20 July 2015

The effect of ethanol on pancreatic enzymes--a dietary artefact?

scientific article published on 01 March 1998

Towards a clinically relevant lentiviral transduction protocol for primary human CD34 hematopoietic stem/progenitor cells

scientific article

Transmission of hepatitis C virus infection among younger and older people who inject drugs in Vancouver, Canada

scientific article published on 25 February 2016

Venue-Based Networks May Underpin HCV Transmissions amongst HIV-Infected Gay and Bisexual Men.

scientific article

Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infection

scientific article published in August 2012

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