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List of works by Miguel A Del Pozo

A Novel Systems-Biology Algorithm for the Analysis of Coordinated Protein Responses Using Quantitative Proteomics

scientific article published on 18 February 2016

A novel high-content analysis tool reveals Rab8-driven cytoskeletal reorganization through Rho GTPases, calpain and MT1-MMP.

scientific article

A palmitoylation switch mechanism regulates Rac1 function and membrane organization.

scientific article

AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts.

scientific article published on 28 November 2017

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.

scientific article

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

scientific article

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

scientific article

An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation

scientific article published on 20 December 2019

CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts ⬇️

scientific article published on June 15, 1998

Caveolae

scientific article published on 01 February 2012

Caveolae - mechanosensitive membrane invaginations linked to actin filaments

scientific article

Caveolae as plasma membrane sensors, protectors and organizers.

scientific article published on February 2013

Caveolae internalization regulates integrin-dependent signaling pathways.

scientific article published on October 2006

Caveolae: The FAQs

scientific article published on 09 September 2019

Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1.

scientific article published on 27 March 2012

Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP

scientific article published on 01 November 2018

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

scientific article published on 30 December 2014

Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.

scientific article

Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.

scientific article published on 14 August 2017

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis

scientific article published on 03 August 2020

Cell-Based Assays to Study ERK Pathway/Caveolin1 Interactions.

scientific article published in January 2017

Cell-based fuzzy metrics enhance high-content screening (HCS) assay robustness

scientific article published on 17 September 2013

Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation

scientific article

Cholesterol-enriched membrane micro-domaindeficiency induces doxorubicin resistancevia promoting autophagy in breast cancer

scientific article published on 20 October 2021

Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation.

scientific article

Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy

scientific article published in January 2015

Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging

scientific article published on 06 February 2019

Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells.

scientific article

Distribution of ICAM-3-bearing cells in normal human tissues. Expression of a novel counter-receptor for LFA-1 in epidermal Langerhans cells.

scientific article published on September 1993

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway.

scientific article

Functional relevance during lymphocyte migration and cellular localization of activated beta1 integrins

scientific article published on 01 January 1997

Hematopoietic cell-type-dependent regulation of leukocyte integrin functional activity: CD11b and CD11c expression inhibits LFA-1-dependent aggregation of differentiated U937 cells.

scientific article

ICAM-3, the third LFA-1 counterreceptor, is a co-stimulatory molecule for both resting and activated T lymphocytes

scientific article published on 01 November 1993

ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer

scientific article

Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.

scientific article published on September 1994

Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells

scientific article

Integrin signaling and lipid rafts.

scientific article published on 28 June 2004

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

scholarly article

Interleukin-15 induces adhesion receptor redistribution in T lymphocytes

scientific article published on 01 June 1996

Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice

scientific article published on 06 June 2016

Intracellular trafficking of raft/caveolae domains: insights from integrin signaling.

scientific article published on 19 August 2007

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

scientific article published on 16 May 2003

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

scientific article published on 01 October 2020

Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP

scientific article published on 04 March 2022

Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells

scientific article published in Nature Communications

Mesenchymal Contribution to Recruitment, Infiltration, and Positioning of Leukocytes in Human Melanoma Tissues

scientific article published in September 2013

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis

scientific article

Overcoming anoikis--pathways to anchorage-independent growth in cancer.

scientific article published in October 2011

Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.

scientific article

Phosphorylated filamin A regulates actin-linked caveolae dynamics.

scientific article published in August 2011

Phosphorylation of filamin A regulates chemokine receptor CCR2 recycling

scientific article published on December 2016

Physical principles of membrane remodelling during cell mechanoadaptation

scientific article

Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells

scientific article published on 01 April 2000

Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs.

scientific article published on April 1995

Protein Localization at Mitochondria-ER Contact Sites in Basal and Stress Conditions.

scientific article published on 12 December 2017

Rac1 nucleocytoplasmic shuttling drives nuclear shape changes and tumor invasion

scientific article published on 29 January 2015

Reduced intracellular oxidative metabolism promotes firm adhesion of human polymorphonuclear leukocytes to vascular endothelium under flow conditions

scientific article published on 01 August 1997

Regulation of ICAM-3 (CD50) membrane expression on human neutrophils through a proteolytic shedding mechanism

scientific article published on 01 November 1994

Role of ICAM-3 in intercellular adhesion and activation of T lymphocytes

scientific article published on 01 July 1994

Role of the Endocytosis of Caveolae in Intracellular Signaling and Metabolism

scientific article published on 01 January 2018

Roles of chemokines and receptor polarization in NK-target cell interactions ⬇️

scientific article published on October 1, 1998

Roles of microtubule dynamics and small GTPase Rac in endothelial cell migration and lamellipodium formation under flow.

scientific article

Spanish scientists working abroad

scientific article

The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: role of cholesterol

scientific article published on 21 September 2014

The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.

scientific article published on 20 July 2009

The chemokine SDF-1alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes.

scientific article published in July 1998

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.

scientific article

The two poles of the lymphocyte: specialized cell compartments for migration and recruitment

scientific article published on 01 January 1998

Tox_(R)CNN: Deep learning-based nuclei profiling tool for drug toxicity screening

article

[Caveolin-1 forces matrix remodeling]

scientific article published on 30 November 2011

p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.

scientific article published on 23 November 2010

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