List of works - Emmanuel Scotet

+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10.

scientific article

A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen.

scientific article

Activated iNKT cells promote Vγ9Vδ2-T cell anti-tumor effector functions through the production of TNF-α.

scientific article published on 4 November 2011

Aminobisphosphonates inhibit dendritic cell-mediated antigen-specific activation of CD1d-restricted iNKT cells.

scientific article

An X-ray Vision for Phosphoantigen Recognition

scientific article published on 01 April 2019

BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia

scientific article published on 25 April 2016

Beyond CAR T cells: Engineered Vγ9Vδ2 T cells to fight solid tumors

scientific article published on 23 September 2020

Bridging innate and adaptive immunity through gammadelta T-dendritic cell crosstalk.

scientific article published on May 2008

Butyrophilin 3A (BTN3A, CD277)-specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation

scientific article published on 6 April 2017

CD1d-restricted antigen presentation by Vγ9Vδ2-T cells requires trogocytosis

scientific article

Combined chemotherapy and allogeneic human Vγ9Vδ2 T lymphocyte-immunotherapies efficiently control the development of human epithelial ovarian cancer cells in vivo

scientific article published on 28 August 2019

Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells.

scientific article published on 05 June 2013

Development of Predictive Value of Urinary Cytokine Profile Induced During Intravesical Bacillus Calmette-Guérin Instillations for Bladder Cancer

scientific article published on 21 January 2015

Early triggering of exclusive IFN-gamma responses of human Vgamma9Vdelta2 T cells by TLR-activated myeloid and plasmacytoid dendritic cells.

scientific article published on 26 August 2009

Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.

scientific article

Exon III splicing switch of fibroblast growth factor (FGF) receptor-2 and -3 can be induced by FGF-1 or FGF-2 ⬇️

scientific article published on July 9, 1998

Full Restoration of Brucella-Infected Dendritic Cell Functionality through Vγ9Vδ2 T Helper Type 1 Crosstalk ⬇️

scientific article published on August 22, 2012

Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumors

scientific article published on 25 July 2006

IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors.

scientific article published on 20 April 2018

IL-21-mediated potentiation of antitumor cytolytic and proinflammatory responses of human V gamma 9V delta 2 T cells for adoptive immunotherapy.

scientific article

Immunodominant CD8 T cell response to Epstein-Barr virus ⬇️

scientific article published on September 1, 2001

Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation

scientific article published on 27 January 2018

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

scientific article

Modulation of inflammation through IL-17 production by gammadelta T cells: mandatory in the mouse, dispensable in humans?

scientific article published on 12 August 2009

Molecular regulation of CC-chemokine receptor 3 expression in human T helper 2 cells

scientific article published on 01 October 2001

Molecules and Mechanisms Implicated in the Peculiar Antigenic Activation Process of Human Vγ9Vδ2 T Cells

scientific article

Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells

scholarly article

NKG2D Controls Natural Reactivity of Vγ9Vδ2 T Lymphocytes against Mesenchymal Glioblastoma Cells

scientific article published on 10 September 2019

NKG2D costimulates human V gamma 9V delta 2 T cell antitumor cytotoxicity through protein kinase C theta-dependent modulation of early TCR-induced calcium and transduction signals.

scientific article

Oncoprotein fos activation in epithelial-cells induces an epitheliomesenchymal conversion and changes the receptor encoded by the fgfr-2 messenger-RNA from k-sam to bek ⬇️

scientific article published on March 1, 1995

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor

scientific article published on 19 May 2016

Self/non-self discrimination by human gammadelta T cells: simple solutions for a complex issue?

scientific article

Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2.

scientific article published on 07 March 2017

Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts

scientific article published on 01 September 2018

Stereotaxic administrations of allogeneic human Vγ9Vδ2 T cells efficiently control the development of human glioblastoma brain tumors.

scientific article published on 30 March 2016

Synergism and complementarity between human CD1 AND MHC-restricted T cells, two lymphoid subsets directed against distinct antigenic worlds.

scientific article

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

scientific article published on 30 March 2017

The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells

scientific article

The Juxtamembrane Domain of Butyrophilin BTN3A1 Controls Phosphoantigen-Mediated Activation of Human Vγ9Vδ2 T Cells.

scientific article

The Molecular Basis for Modulation of Human V 9V 2 T Cell Responses by CD277/Butyrophilin-3 (BTN3A)-specific Antibodies

scientific article

The interplay between the duration of TCR and cytokine signaling determines T cell polarization

scientific article published on 01 December 1999

Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells.

scientific article

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I

scientific article published on 01 January 2005

Up-regulation of cytolytic functions of human Vδ2-γ T lymphocytes through engagement of ILT2 expressed by tumor target cells

scientific article

Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.

scientific article

List of works by Emmanuel Scotet

+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10.

A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen.

Activated iNKT cells promote Vγ9Vδ2-T cell anti-tumor effector functions through the production of TNF-α.

Aminobisphosphonates inhibit dendritic cell-mediated antigen-specific activation of CD1d-restricted iNKT cells.

An X-ray Vision for Phosphoantigen Recognition

BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia

Beyond CAR T cells: Engineered Vγ9Vδ2 T cells to fight solid tumors

Bridging innate and adaptive immunity through gammadelta T-dendritic cell crosstalk.

Butyrophilin 3A (BTN3A, CD277)-specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation

CD1d-restricted antigen presentation by Vγ9Vδ2-T cells requires trogocytosis

Combined chemotherapy and allogeneic human Vγ9Vδ2 T lymphocyte-immunotherapies efficiently control the development of human epithelial ovarian cancer cells in vivo

Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells.

Development of Predictive Value of Urinary Cytokine Profile Induced During Intravesical Bacillus Calmette-Guérin Instillations for Bladder Cancer

Early triggering of exclusive IFN-gamma responses of human Vgamma9Vdelta2 T cells by TLR-activated myeloid and plasmacytoid dendritic cells.

Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.

Exon III splicing switch of fibroblast growth factor (FGF) receptor-2 and -3 can be induced by FGF-1 or FGF-2 ⬇️

Full Restoration of Brucella-Infected Dendritic Cell Functionality through Vγ9Vδ2 T Helper Type 1 Crosstalk ⬇️

Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumors

IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors.

IL-21-mediated potentiation of antitumor cytolytic and proinflammatory responses of human V gamma 9V delta 2 T cells for adoptive immunotherapy.

Immunodominant CD8 T cell response to Epstein-Barr virus ⬇️

Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

Modulation of inflammation through IL-17 production by gammadelta T cells: mandatory in the mouse, dispensable in humans?

Molecular regulation of CC-chemokine receptor 3 expression in human T helper 2 cells

Molecules and Mechanisms Implicated in the Peculiar Antigenic Activation Process of Human Vγ9Vδ2 T Cells

Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells

NKG2D Controls Natural Reactivity of Vγ9Vδ2 T Lymphocytes against Mesenchymal Glioblastoma Cells

NKG2D costimulates human V gamma 9V delta 2 T cell antitumor cytotoxicity through protein kinase C theta-dependent modulation of early TCR-induced calcium and transduction signals.

Oncoprotein fos activation in epithelial-cells induces an epitheliomesenchymal conversion and changes the receptor encoded by the fgfr-2 messenger-RNA from k-sam to bek ⬇️

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor

Self/non-self discrimination by human gammadelta T cells: simple solutions for a complex issue?

Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2.

Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts

Stereotaxic administrations of allogeneic human Vγ9Vδ2 T cells efficiently control the development of human glioblastoma brain tumors.

Synergism and complementarity between human CD1 AND MHC-restricted T cells, two lymphoid subsets directed against distinct antigenic worlds.

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells

The Juxtamembrane Domain of Butyrophilin BTN3A1 Controls Phosphoantigen-Mediated Activation of Human Vγ9Vδ2 T Cells.

The Molecular Basis for Modulation of Human V 9V 2 T Cell Responses by CD277/Butyrophilin-3 (BTN3A)-specific Antibodies

The interplay between the duration of TCR and cytokine signaling determines T cell polarization

Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells.

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I

Up-regulation of cytolytic functions of human Vδ2-γ T lymphocytes through engagement of ILT2 expressed by tumor target cells

Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.