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List of works by Marc Bickle

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

scientific article published on 27 January 2014

A Combination of Screening and Computational Approaches for the Identification of Novel Compounds That Decrease Mast Cell Degranulation

scientific article published on 2 April 2015

A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death

scientific article

A comparative analysis of perturbations caused by a gene knock-out, a dominant negative allele, and a set of peptide aptamers.

scientific article published on 4 September 2007

A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis

scientific article

A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking

scientific article published on 2 October 2014

Age-dependent labeling and imaging of insulin secretory granules

scientific article published on 8 August 2013

An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity

scientific article published on 4 December 2006

Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers

scientific article

CellProfiler and KNIME: Open-Source Tools for High-Content Screening

scientific article published on 01 January 2019

CellProfiler and KNIME: open source tools for high content screening

scientific article published on January 2013

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

scientific article

Concerns, challenges and promises of high-content analysis of 3D cellular models

scientific article published on 06 July 2018

Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery

scientific article published on 30 May 2019

Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen

scientific article published on 30 January 2014

Development of a Kinetic Assay for Late Endosome Movement

scientific article published on 20 February 2014

Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo

scientific article published on 14 February 2019

Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome

scientific article published on 14 June 2016

High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells

scientific article published on 13 February 2015

High-content screening: a new primary screening tool?

scientific article

Identification of siRNA delivery enhancers by a chemical library screen

scientific article published on 28 July 2015

Image analysis in high-content screening

scientific article

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape

scientific article published on 23 June 2013

In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay

Inhibition of vaccinia virus replication by peptide aptamers

scientific article

Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing ⬇️

scientific article published on February 13, 2013

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

scientific article

Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins

scientific article published on 20 February 2020

Layer-by-Layer Assembly of Heparin and Peptide-Polyethylene Glycol Conjugates to Form Hybrid Nanothin Films of Biomatrices

scientific article published on 17 April 2018

Live-Cell High Content Screening in Drug Development

scientific article published in January 2018

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model.

scientific article published on 20 November 2013

Multilineage communication regulates human liver bud development from pluripotency.

scientific article published on 14 June 2017

Peptide aptamers for small molecule drug discovery

scientific article

Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution

scientific article published in Nature Communications

Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.

scientific article

Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells

scientific article published on 13 September 2017

Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

scientific article published on 13 February 2019

RNA buffers the phase separation behavior of prion-like RNA binding proteins.

scientific article published on 12 April 2018

SLAS Europe High-Content Screening Conference in Dresden: A Glimpse of the Future?

scientific article published in October 2016

Screening out irrelevant cell-based models of disease

scientific article published on 12 September 2016

Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

scientific article

Systems drug discovery: a quantitative, objective approach for safer drug development

scientific article published on 25 July 2012

The Academic Pill: How Academia Contributes to Curing Diseases

scientific article published on 01 March 2019

The King Is Dead, Long Live the King! JBS Special Issue on Screening by RNAi and Precise Genome Editing Technologies

scientific article published on 01 September 2015

The beautiful cell: high-content screening in drug discovery

scientific article published on 25 June 2010

The technology development studio of the MPI-CBG: an open access cell-based screening facility

scientific article

Unbiased Phenotype Detection Using Negative Controls

scientific article published on 07 January 2019

Unbiased Screens for Modifiers of Alpha-Synuclein Toxicity

scientific article published on 09 February 2019

Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner

scientific article published on 22 October 2019

Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells

scientific article published on 21 September 2017

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