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List of works by Cathrin Brisken

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

scientific article published on March 2016

A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids

scientific article published on 25 July 2019

A new Achilles Heel in breast cancer?

scientific article published on August 2013

A novel culture method that sustains ERα signaling in human breast cancer tissue microstructures

scientific article published on 17 August 2020

A paracrine role for the epithelial progesterone receptor in mammary gland development ⬇️

scientific article published on April 28, 1998

ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

scientific article published in 2022

Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development.

scientific article published on 16 September 2016

Alveolar and lactogenic differentiation

scientific article published on October 2006

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development

scientific journal article

Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics

scientific article

An ex vivo model to study hormone action in the human breast

scientific article

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

scientific article published in January 2007

Analysis of Mammary Gland Phenotypes by Transplantation of the Genetically Marked Mammary Epithelium

scientific article published in January 2017

C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells

scientific article published on 02 August 2019

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis

scientific journal article

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity

scientific article published on 15 July 2020

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

scientific article

Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis

scientific article

Corrigendum: Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

scientific article published on 01 October 2015

Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression

scientific article

Does cancer start in the womb? altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors.

scientific article published on 24 May 2013

ER and PR signaling nodes during mammary gland development

scientific article published on 19 July 2012

Endocrine Disruptors and Breast Cancer

Endocrine hormones and local signals during the development of the mouse mammary gland.

scientific article

Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.

scientific article published in July 2008

Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells

scientific article

Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor

scientific article published on 06 June 2022

From normal cell types to malignant phenotypes

scientific article

High hopes for RANKL: will the mouse model live up to its promise?

scientific article

Hormonal control of alveolar development and its implications for breast carcinogenesis

scientific article

Hormone action in the mammary gland

scientific article

ID4 regulates mammary gland development by suppressing p38MAPK activity

scientific article published on December 2011

IGF-2 is a mediator of prolactin-induced morphogenesis in the breast

scientific article published in December 2002

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

scientific article published on 06 July 2020

Identification of molecular apocrine breast tumours by microarray analysis.

scientific article published on July 2005

In vivo reprogramming of non-mammary cells to an epithelial cell fate is independent of amphiregulin signaling

scientific article published on 28 April 2017

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

scientific article

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

scientific article published on 27 December 2018

Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

scientific article published on 22 February 2021

Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium

scientific article published on 11 March 2020

Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy

scientific article published on 4 July 2013

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

scientific article published in Nature Communications

Optimized Modeling of Metastatic Triple-Negative Invasive Lobular Breast Carcinoma

scientific article published in 2023

Paracrine signaling by progesterone

scientific article published on 16 September 2011

Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland

scholarly article

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

scientific article published on 27 December 2016

Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number.

scientific article

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis

scientific article (publication date: October 2015)

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk

scientific article

Progesterone signalling in breast cancer: a neglected hormone coming into the limelight

scientific article published on June 2013

Progesterone signalling in the normal breast and its implications for cancer

scientific article published on 01 June 2020

Progesterone/RANKL is a major regulatory axis in the human breast

scientific article published in April 2013

Prolactin signaling and Stat5: going their own separate ways?

scientific article

Reply to Is progesterone a neutral or protective factor for breast cancer?

scientific article published on 20 January 2014

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective.

scientific article published on June 2007

Stem cells in chemical carcinogenesis

scientific article published on 26 November 2009

The Ret receptor tyrosine kinase pathway functionally interacts with the ERalpha pathway in breast cancer

scientific article

The challenges of modeling hormone receptor-positive breast cancer in mice

scientific article published on 21 March 2018

The epithelial-mesenchymal transition generates cells with properties of stem cells

scientific article

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

scientific article published on 26 March 2020

The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium

scientific article

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

scientific article

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.

scientific article

Two-Tier Mapper, an unbiased topology-based clustering method for enhanced global gene expression analysis

scientific article published on 01 September 2019

Using gene expression arrays to elucidate transcriptional profiles underlying prolactin function

scientific article published on July 2003

What signals operate in the mammary niche?

scientific article published on 01 January 2008

miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1.

scientific article published on 11 December 2012

p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation

scientific article

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