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List of works by Wim Vanden Berghe

(-)-Epicatechin metabolites promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation

scientific article published on 20 November 2019

A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein

scientific article published in April 2007

A fully dissociated compound of plant origin for inflammatory gene repression

scientific article

A genome-wide search for epigenetically [corrected] regulated genes in zebra finch using MethylCap-seq and RNA-seq

scientific article

A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis

scientific article published on February 2008

A primer to frequent itemset mining for bioinformatics

scientific article

Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a.

scientific article

Acculturation Strategies and Mental Health in Gay, Lesbian, and Bisexual Youth ⬇️

scientific article published on July 14, 2009

Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

scientific article

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

scientific article

Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma

scientific article published on 01 February 2020

Assessment of the cytotoxic potential of an aqueous-ethanolic extract from Thalassia testudinum angiosperm marine grown in the Caribbean Sea

scientific article published on 30 August 2018

Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity.

scientific article published in May 2006

Back to the future: Epigenetic clock plasticity towards healthy aging

scientific article published on 11 January 2018

Bioinformatics approaches for the functional interpretation of protein lists: from ontology term enrichment to network analysis

scientific article published on 20 February 2015

Characterization of Blood Surrogate Immune-Methylation Biomarkers for Immune Cell Infiltration in Chronic Inflammaging Disorders

scientific article published on 27 November 2019

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

scientific article (publication date: 2013)

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model

scientific article published on 11 August 2019

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

scientific article

Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response

DFNA5 promoter methylation a marker for breast tumorigenesis

scientific article

DNA Binding-Independent Induction of I B Gene Transcription by PPAR

article

DNA-based monitoring of the alien invasive North American crayfish Procambarus clarkii in Andean lakes (Ecuador)

scientific article published on 18 March 2018

Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration

scientific article published on 02 July 2012

Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

scientific article

Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation

scientific article published on 2 December 2009

Dry amorphisation of mangiferin, a poorly water-soluble compound, using mesoporous silica

scientific article published on 29 May 2019

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

scientific article published on 12 May 2021

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells

scientific article

Epigenetic control of cardiovascular health by nutritional polyphenols involves multiple chromatin-modifying writer-reader-eraser proteins.

scientific article published on 25 August 2015

Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes.

scientific article published on 22 March 2012

Epigenetic remedies by dietary phytochemicals against inflammatory skin disorders: myth or reality?

scientific article published on June 2010

Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A.

scientific article published on 13 April 2017

Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma

scientific article published on 10 February 2017

Estrogen receptor signaling is an unstable feature of the gonadotropic LbetaT2 cell line.

scientific article

Estrogenic and anticarcinogenic properties of kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens.

scientific article published in November 2004

From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?

scientific article

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy.

scientific article published on 11 April 2018

Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators

Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: possible partners in the combat against inflammation

scientific article published on 27 December 2008

Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha

scientific article published on 04 April 2007

How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering.

scientific article published on 23 December 2012

Identification and functional characterization of the human EXT1 promoter region.

scientific article published on 19 October 2011

Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor.

scientific article published on 26 February 2018

In Vitro Neuroprotective and Anti-Inflammatory Activities of Natural and Semi-Synthetic Spirosteroid Analogues.

scientific article published on 29 July 2016

Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ

scientific article

Inhibition of cytokine production by the herbicide atrazine. Search for nuclear receptor targets

scientific article

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

scientific article published in July 2005

Inhibition of the NF-κB signaling pathway by a novel heterocyclic curcumin analogue.

scientific article

Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk-an exploratory study

scientific article published on 05 April 2017

Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics.

scientific article published on 24 August 2006

LC-MS Characterization and Biological Activities of Cuban Cultivars of Plectranthus neochilus Schltr

scientific article published in 2022

Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer

scientific article

Lower Placental Leptin Promoter Methylation in Association with Fine Particulate Matter Air Pollution during Pregnancy and Placental Nitrosative Stress at Birth in the ENVIRONAGE Cohort.

scientific article published on 13 September 2016

Medroxyprogesterone acetate downregulates cytokine gene expression in mouse fibroblast cells.

scientific article published on June 2004

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

scientific article published on 16 April 2019

Methylglyoxal suppresses TNF-alpha-induced NF-kappaB activation by inhibiting NF-kappaB DNA-binding

scientific article

Molecular insight in the multifunctional activities of Withaferin A.

scientific article

Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemical withaferin A.

scientific article published on 6 February 2017

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

scholarly article by Behrouz Hassannia et al published 1 August 2018 in Journal of Clinical Investigation

Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders.

scientific article

Non-Methylation-Linked Mechanism of REST-Induced Neuroglobin Expression Impacts Mitochondrial Phenotypes in a Mouse Model of Amyotrophic Lateral Sclerosis

scientific article published on 31 May 2019

Novel selective glucocorticoid receptor agonists (SEGRAs) with a covalent warhead for long-lasting inhibition.

scientific article published on 31 August 2016

Peptides as epigenetic modulators: therapeutic implications

scientific article published on 12 July 2019

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

scientific article published in Journal of Biological Chemistry

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

scientific article published on 03 February 2014

Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions ⬇️

scientific article published on 14 December 2017

Proteomic characterization of Withaferin A-targeted protein networks for the treatment of monoclonal myeloma gammopathies.

scientific article published on 12 February 2018

Rapanone, a naturally occurring benzoquinone, inhibits mitochondrial respiration and induces HepG2 cell death

scientific article published on 20 November 2019

Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor

scientific article published on July 1997

Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures

scientific article published on 29 April 2014

Regulation of prolactin expression in leukemic cell lines and peripheral blood mononuclear cells.

scientific article

Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit.

scientific article

Role of glucocorticoids in dopamine-related neuropsychiatric disorders

scientific article

SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data.

scientific article

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

scientific article

Salivary DNA Methylation Profiling: Aspects to Consider for Biomarker Identification

scientific article published on 30 November 2016

Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads

scientific article published in November 2017

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

scientific article published on 20 June 2013

Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution.

scientific article

Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections. Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy.

scientific article published in September 2004

Tackling Chronic Inflammation with Withanolide Phytochemicals-A Withaferin a Perspective

scientific article published on 10 November 2020

The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8/9 Inhibition Attenuates M1 Macrophage Activation in Mice

scientific article published on 10 October 2015

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

scientific article published on 14 September 2018

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

scientific article

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

scientific article published on November 1999

The risk for behavioural deficits is determined by the maternal immune response to prenatal immune challenge in a neurodevelopmental model.

scientific article published on 26 June 2014

The versatile role of MSKs in transcriptional regulation.

scientific article published on 21 May 2009

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

scientific article

Whole-Genome Saliva and Blood DNA Methylation Profiling in Individuals with a Respiratory Allergy

scientific article

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

scientific article

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ.

scientific article published on 23 August 2014

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

scientific article

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

scientific article

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