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List of works by Sean G Rudd

Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

scientific article published on 01 November 2019

Cell Cycle Profiling Reveals Protein Oscillation, Phosphorylation, and Localization Dynamics

scientific article published on 12 February 2020

Development of a chemical probe against NUDT15

scientific article published on 20 July 2020

Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.

scientific article

Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens

scholarly article by George Z Rassidakis et al published 19 October 2018 in Blood Cancer Journal

MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG

scientific article published on 20 April 2020

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

scientific article published on 15 July 2021

Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism

PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome

scientific article published in November 2013

Pathways controlling dNTP pools to maintain genome stability

scientific article published on 28 May 2016

PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication

scientific article

PrimPol-A new polymerase on the block

scientific article published on April 2014

Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy

scientific article published on 17 January 2020

SAMHD1 is a barrier to antimetabolite-based cancer therapies.

scientific article published on 3 February 2017

SAMHD1 protects cancer cells from various nucleoside-based antimetabolites

scientific article

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

scientific article published on 17 January 2018

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

scientific article

Validation and development of MTH1 inhibitors for treatment of cancer.

scientific article

With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.

scientific article published on 11 May 2017

hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia

scientific article published on 5 December 2016

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