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List of works by Zhongjun Zhou

'Relax and Repair' to restrain aging.

scientific article published on October 2011

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.

scientific article published on 7 October 2015

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

scientific article published on 23 July 2018

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

scientific article

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.

scientific article

CIA2 deficiency results in impaired oxidative stress response and enhanced intracellular basal UPR activity in Saccharomyces cerevisiae

scientific article published on 8 February 2015

Chromatin remodeling, DNA damage repair and aging.

scientific article

Combinatorial use of offline SCX and online RP–RP liquid chromatography for iTRAQ-based quantitative proteomics applications

scientific article published on 25 February 2011

Defective ATM‐Kap‐1‐mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model ⬇️

scientific article published on December 21, 2012

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice

scientific article published in April 2002

Deletion of laminin-8 results in increased tumor neovascularization and metastasis in mice.

scientific article published in June 2004

Deletion of the lmna gene induces growth delay and serum biochemical changes in C57BL/6 mice

scientific article

Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14.

scientific article published on 31 March 2010

Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model ⬇️

scientific article published on January 1, 2013

Distinct spatiotemporal expression of ISM1 during mouse and chick development.

scientific article

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex

scientific article

Facile synthesis of novel magnetic silica nanoparticles functionalized with layer-by-layer detonation nanodiamonds for secretome study

scientific article published on 15 October 2015

From loss to gain: role for SUN1 in laminopathies.

scientific article published on 18 June 2012

Genetics of aging, progeria and lamin disorders

scientific article published on June 2014

Genomic instability in laminopathy-based premature aging

scientific article

Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice

scientific article published on 23 February 2018

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

scientific article

ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development

scientific article published on 06 June 2019

Identification of FAM96B as a novel prelamin A binding partner

scientific article

Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice

scientific article

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

scholarly article

Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair.

scientific article published on 4 November 2015

Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model

scientific article published on 20 March 2019

MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development ⬇️

scientific article published on May 13, 2011

MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis

scientific article published on 24 May 2012

MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis

scientific article published on March 2016

MT1-MMP-mediated cleavage of decorin in corneal angiogenesis.

scientific article published on 30 June 2009

Matrix metalloproteinase 14 modulates signal transduction and angiogenesis in the cornea.

scientific article

MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts

scientific article published on 24 April 2015

Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase

scientific article published on 31 January 2014

Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells

scientific article published on 19 September 2007

Novel aspects of corneal angiogenic and lymphangiogenic privilege.

scientific article published on 25 January 2010

PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae

scientific article published on 4 May 2015

Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels.

scientific article published in September 2005

Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast.

scientific article

Resveratrol activates SIRT1 in a Lamin A-dependent manner.

scientific article published on 25 February 2013

Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria

scientific article

SIRTain regulators of premature senescence and accelerated aging

scientific article

Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair.

scientific article published on 26 September 2006

Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs

scientific article published on 24 March 2020

Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.

scientific article published on 19 February 2018

TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging.

scientific article

TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent

scientific article published on September 2008

The association of a single nucleotide polymorphism in the promoter region of the LAMA1 gene with susceptibility to Chinese high myopia.

scientific article

Trinations aging symposium.

scientific article published on June 2011

Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model

scientific article published on 19 February 2020

When MT1-MMP meets ADAMs ⬇️

scientific article published on August 1, 2012

Wound Healing in Membrane-Type-1 Matrix Metalloproteinase-Deficient Mice11Presented, in part, at the Joint meeting of the European Tissue Repair Society and Wound Healing Society, Baltimore, May 2002 and awarded First Prize in the Young Investigators

scientific article published on 01 September 2004

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