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List of works by Zhongjun Zhou

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Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

scholarly article
Genomic instability in laminopathy-based premature aging

scientific article
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice

scientific article published in April 2002
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

scientific article
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

scientific article
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice

scientific article
A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.

scientific article published on 7 October 2015
Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14.

scientific article published on 31 March 2010
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria

scientific article
Novel aspects of corneal angiogenic and lymphangiogenic privilege.

scientific article published on 25 January 2010
Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels.

scientific article published in September 2005
Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model

scientific article published on January 1, 2013
Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair.

scientific article published on 4 November 2015
Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells

scientific article published on 19 September 2007
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis

scientific article published on 24 May 2012
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent

scientific article published on September 2008
MT1-MMP-mediated cleavage of decorin in corneal angiogenesis.

scientific article published on 30 June 2009
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis

scientific article published on March 2016
Genetics of aging, progeria and lamin disorders

scientific article published on June 2014
MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development

scientific article published on May 13, 2011
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex

scientific article
Deletion of laminin-8 results in increased tumor neovascularization and metastasis in mice.

scientific article published in June 2004
Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.

scientific article published on 19 February 2018
Chromatin remodeling, DNA damage repair and aging.

scientific article
Defective ATM‐Kap‐1‐mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model

scientific article published on December 21, 2012
A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

scientific article published on 23 July 2018
Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast.

scientific article
Resveratrol activates SIRT1 in a Lamin A-dependent manner.

scientific article published on 25 February 2013
Combinatorial use of offline SCX and online RP–RP liquid chromatography for iTRAQ-based quantitative proteomics applications

scientific article published on 25 February 2011
Matrix metalloproteinase 14 modulates signal transduction and angiogenesis in the cornea.

scientific article
TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging.

scientific article
SIRTain regulators of premature senescence and accelerated aging

scientific article
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae

scientific article published on 4 May 2015
Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

scientific article
'Relax and Repair' to restrain aging.

scientific article published on October 2011
The association of a single nucleotide polymorphism in the promoter region of the LAMA1 gene with susceptibility to Chinese high myopia.

scientific article
When MT1-MMP meets ADAMs

scientific article published on August 1, 2012
Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase

scientific article published on 31 January 2014
Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair.

scientific article published on 26 September 2006
Distinct spatiotemporal expression of ISM1 during mouse and chick development.

scientific article
Wound Healing in Membrane-Type-1 Matrix Metalloproteinase-Deficient Mice11Presented, in part, at the Joint meeting of the European Tissue Repair Society and Wound Healing Society, Baltimore, May 2002 and awarded First Prize in the Young Investigators

scientific article published on 01 September 2004
Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice

scientific article published on 23 February 2018
CIA2 deficiency results in impaired oxidative stress response and enhanced intracellular basal UPR activity in Saccharomyces cerevisiae

scientific article published on 8 February 2015
From loss to gain: role for SUN1 in laminopathies.

scientific article published on 18 June 2012
Deletion of the lmna gene induces growth delay and serum biochemical changes in C57BL/6 mice

scientific article
Identification of FAM96B as a novel prelamin A binding partner

scientific article
MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts

scientific article published on 24 April 2015
Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model

scientific article published on 20 March 2019
Trinations aging symposium.

scientific article published on June 2011
Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs

scientific article published on 24 March 2020

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