List of works - Caroline Barette

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras

scientific article published on March 2015

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.

scientific article published on 20 August 2013

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

scientific article

Antitumoral activity of allosteric inhibitors of protein kinase CK2.

scientific article

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

scientific article

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

scientific article

Chimeric Protein-Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence

scientific article published on 27 September 2019

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features.

scientific article

Expanding the chemical diversity of CK2 inhibitors.

scientific article

Functional characterization of cell-free expressed Kv1.3 channel using a voltage-sensitive fluorescent dye.

scientific article published on 20 January 2018

Förster Resonance Energy Transfer Based Biosensor for Targeting the hNTH1-YB1 Interface as a Potential Anticancer Drug Target

scientific article published on 17 March 2020

High-Content Screening Identifies New Inhibitors of Connexin 43 Gap Junctions

scientific article published on 01 July 2019

Improving detection of rare biological events in high-throughput screens

scientific article

Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine.

scientific article published on 10 May 2012

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

scientific article published on 28 April 2006

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

scientific article

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.

scientific article published in January 2015

Parthenolide inhibits tubulin carboxypeptidase activity

scientific article published on 01 April 2007

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

scientific article

Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator

scientific article

Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.

scientific article

Screening for biologically annotated drugs that trigger triacylglycerol accumulation in the diatom Phaeodactylum.

scientific article published on 13 March 2018

Single assay-wide variance experimental (SAVE) design for high-throughput screening

scientific article

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

article

Strength and specificity of the CMBA screening platform for bioactive molecules discovery

scientific article

Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit.

scientific article published on 10 November 2015

List of works by Caroline Barette

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

Antitumoral activity of allosteric inhibitors of protein kinase CK2.

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

Chimeric Protein-Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features.

Expanding the chemical diversity of CK2 inhibitors.

Functional characterization of cell-free expressed Kv1.3 channel using a voltage-sensitive fluorescent dye.

Förster Resonance Energy Transfer Based Biosensor for Targeting the hNTH1-YB1 Interface as a Potential Anticancer Drug Target

High-Content Screening Identifies New Inhibitors of Connexin 43 Gap Junctions

Improving detection of rare biological events in high-throughput screens

Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine.

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.

Parthenolide inhibits tubulin carboxypeptidase activity

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator

Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.

Screening for biologically annotated drugs that trigger triacylglycerol accumulation in the diatom Phaeodactylum.

Single assay-wide variance experimental (SAVE) design for high-throughput screening

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

Strength and specificity of the CMBA screening platform for bioactive molecules discovery

Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit.