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List of works by Simona Scheggi

5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction

scientific article published on 24 September 2018

Acquisition and expression of conditioned taste aversion differentially affects extracellular signal regulated kinase and glutamate receptor phosphorylation in rat prefrontal cortex and nucleus accumbens.

scientific article published on 7 May 2014

Acquisition of a palatable-food-sustained appetitive behavior in satiated rats is dependent on the dopaminergic response to this food in limbic areas.

scientific article published in January 2003

Acquisition of an appetitive behavior reverses the effects of long-term treatment with lithium in rats.

scientific article published in January 2000

Antidepressant and pro-motivational effects of repeated lamotrigine treatment in a rat model of depressive symptoms

Aripiprazole relieves motivational anhedonia in rats.

scientific article published on 20 October 2017

DARPP-32 in the orchestration of responses to positive natural stimuli

scientific article published on 06 November 2018

Dizocilpine infusion has a different effect in the development of morphine and cocaine sensitization: behavioral and neurochemical aspects.

scientific article published in January 2002

Dopamine D1 receptor-dependent modifications in the dopamine and cAMP-regulated phosphoprotein of Mr 32 kDa phosphorylation pattern in striatal areas of morphine-sensitized rats.

scientific article published on 25 June 2009

Effects of the 5-HT(6) receptor agonist ST 1936 on depression- and anhedonia-like experimental models.

scientific article

Fasting biases μ-opioid receptors toward β-arrestin2-dependent signaling in the accumbens shell

scientific article

Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation

scientific article published on 01 February 2019

Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats.

scientific article

Impramine, fluoxetine and clozapine differently affected reactivity to positive and negative stimuli in a model of motivational anhedonia in rats

scientific article

Long-term lithium administration abolishes the resistance to stress in rats sensitized to morphine

scientific article published on 01 September 2000

Making Sense of Rodent Models of Anhedonia

scholarly article by Simona Scheggi et al published 1 November 2018 in The International Journal of Neuropsychopharmacology

Modifications in DARPP-32 phosphorylation pattern after repeated palatable food consumption undergo rapid habituation in the nucleus accumbens shell of non-food-deprived rats.

scientific article published on 6 November 2009

Morphine sensitization as a model of mania: comparative study of the effects of repeated lithium or carbamazepine administration.

scientific article published on July 2011

Noradrenergic terminals are the primary source of α2-adrenoceptor mediated dopamine release in the medial prefrontal cortex

scientific article published on 23 November 2018

PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings

scientific article published on 27 May 2013

PPARα modulation of mesolimbic dopamine transmission rescues depression-related behaviors

scientific article published on 22 July 2016

PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors.

scientific article

Rats sensitized to morphine are resistant to the behavioral effects of an unavoidable stress

scientific article published on 01 January 2000

Repeated acetyl-l-carnitine administration increases phospho-Thr34 DARPP-32 levels and antagonizes cocaine-induced increase in Cdk5 and phospho-Thr75 DARPP-32 levels in rat striatum.

scientific article published in March 2004

Sardinian alcohol-preferring rats show low 5-HT extraneuronal levels in the mPFC and no habituation in monoaminergic response to repeated ethanol consumption in the NAcS.

scientific article published in April 2004

Selective modifications in the nucleus accumbens of dopamine synaptic transmission in rats exposed to chronic stress.

scientific article published in November 2002

Sex-specific differences in cannabinoid-induced extracellular-signal-regulated kinase phosphorylation in the cingulate cortex, prefrontal cortex, and nucleus accumbens of Lister Hooded rats.

scientific article published on 27 March 2018

Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences

scientific article published on 27 July 2020

The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation.

scientific article

The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli

scientific article published on 19 November 2019

The adverse effects of pramipexole on probability discounting are not reversed by acute D2 or D3 receptor antagonism

scientific article published on 24 January 2020

The effects of long-term administration of rubidium or lithium on reactivity to stress and on dopamine output in the nucleus accumbens in rats.

scientific article published in May 1999

The efficacy of reboxetine in preventing and reverting a condition of escape deficit in rats.

scientific article published in May 2003

The mesolimbic dopaminergic response to novel palatable food consumption increases dopamine-D1 receptor-mediated signalling with complex modifications of the DARPP-32 phosphorylation pattern.

scientific article

The protective effect of Hypericum connatum on stress-induced escape deficit in rat is related to its flavonoid content.

scientific article published on 5 January 2016

Using sertraline in postpartum and breastfeeding: balancing risks and benefits

scientific article published on 05 July 2018

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