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List of works by Shyuan T Ngo

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior

scientific article published on 23 November 2017

Altered Metabolic Homeostasis in Amyotrophic Lateral Sclerosis: Mechanisms of Energy Imbalance and Contribution to Disease Progression.

scientific article

Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis

scientific article published on 06 July 2015

Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis

scientific article published on 24 September 2020

Anthropometric measures are not accurate predictors of fat mass in ALS.

scientific article published on 27 April 2017

Biomarkers of Metabolism in Amyotrophic Lateral Sclerosis

scientific article published on 18 March 2019

Body mass index and dietary intervention: implications for prognosis of amyotrophic lateral sclerosis.

scientific article published on 03 March 2014

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

preprint

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

scholarly article

Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis

scientific article

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.

scientific article published on 20 September 2017

Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles.

scientific article published on 13 September 2016

Dysregulation of microRNA biogenesis machinery and microRNA/RNA ratio in skeletal muscle of amyotrophic lateral sclerosis mice.

scientific article published on 13 December 2017

Effect of Deletion of Ghrelin-O-Acyltransferase on the Pulsatile Release of Growth Hormone in Mice

scientific article published on 7 October 2015

Endocrine rhythms of growth hormone release: Insights from animal studies.

scientific article published on 8 November 2017

Exploring targets and therapies for amyotrophic lateral sclerosis: current insights into dietary interventions

scientific article published on 25 July 2017

Gender differences in autoimmune disease

scientific article

Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice

scientific article published on 9 October 2013

Gut microbiota in ALS: possible role in pathogenesis?

scientific article published on 29 May 2019

Hypermetabolism in ALS is associated with greater functional decline and shorter survival

scientific article published on 29 April 2018

Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis.

scientific article published on 23 May 2012

Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain.

scientific article published on 13 July 2013

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

scientific article published on 20 August 2020

Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis

scientific article published on 30 May 2019

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

scientific article published on 26 March 2021

Muscle specific kinase: organiser of synaptic membrane domains

scientific article published on 23 October 2010

Neural agrin increases postsynaptic ACh receptor packing by elevating rapsyn protein at the mouse neuromuscular synapse.

scientific article

Neural agrin: a synaptic stabiliser.

scientific article published on 25 October 2006

Neuregulin potentiates agrin-induced acetylcholine receptor clustering in myotubes

scientific article

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation.

scientific article

Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease.

scientific article published on 23 January 2018

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.

scientific article published on 5 July 2010

Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction

scientific article published on 08 September 2018

Prognostic value of weight loss in patients with amyotrophic lateral sclerosis

scientific article published on 23 June 2020

Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction.

scientific article

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

scientific article published on 27 February 2020

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

scientific article published in March 2010

The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gain.

scientific article published on 16 July 2012

The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies

scientific article published on 26 August 2016

The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis.

scientific article published on 27 August 2015

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice.

scientific article published on 20 April 2012

Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis

scientific article

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