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List of works by Neil Marsh

A short and efficient synthesis of L-5,5,5,5',5',5'-hexafluoroleucine from N-Cbz-L-serine

scientific article published on 01 November 2002

Adenosyl radical: reagent and catalyst in enzyme reactions.

scientific article

Adenosylcobalamin enzymes: Theory and experiment begin to converge ⬇️

scientific article published on 03 April 2012

Adenosylcobalamin-dependent glutamate mutase: examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties

scientific article published on 01 December 1997

Aldehyde Decarbonylases: Enigmatic Enzymes of Hydrocarbon Biosynthesis

scientific article (publication date: November 2013)

Aldehyde-forming fatty acyl-CoA reductase from cyanobacteria: expression, purification and characterization of the recombinant enzyme.

scientific article published on 23 August 2013

Cation-pi interactions studied in a model coiled-coil peptide

scientific article

Cloning and sequencing of glutamate mutase component E from Clostridium tetanomorphum. Organization of the mut genes.

scientific article published on February 1993

Coiled-Coil-Mediated Assembly of an Icosahedral Protein Cage with Extremely High Thermal and Chemical Stability

scientific article published on 29 May 2019

Comparison of the influence of humidity and D-mannitol on the organization of tetraethylene glycol-terminated self-assembled monolayers and immobilized antimicrobial peptides.

scientific article published on 9 June 2014

Comparison of the structures and stabilities of coiled‐coil proteins containing hexafluoroleucine and t‐butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side‐chains ⬇️

scientific article published on October 1, 2012

Conjugation Dependent Interaction of Folic Acid with Folate Binding Protein.

scientific article published on 21 July 2017

Conversion of (3S,4R)-tetrahydrodaidzein to (3S)-equol by THD reductase: proposed mechanism involving a radical intermediate.

scientific article published in July 2010

Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase

scientific article published on 01 August 1998

Covalent Metal−Peptide Framework Compounds That Extend in One and Two Dimensions

Crystallization and preliminary X-ray diffraction studies of a monooxygenase from Streptomyces coelicolor A3(2) involved in the biosynthesis of the polyketide actinorhodin

scientific article published on 01 April 2000

Design, synthesis, and study of fluorinated proteins.

scientific article

Deuterium isotope effects in the unusual addition of toluene to fumarate catalyzed by benzylsuccinate synthase.

scientific article published on November 2006

Effect of Surface Crowding and Surface Hydrophilicity on the Activity, Stability and Molecular Orientation of a Covalently Tethered Enzyme.

scientific article published on 27 June 2017

Effect of immobilization site on the orientation and activity of surface-tethered enzymes

scientific article published on 13 December 2017

Elaborating a coiled-coil-assembled octahedral protein cage with additional protein domains

scientific article published on 03 October 2018

Electronic structure studies of the adenosylcobalamin cofactor in glutamate mutase.

scientific article

Engineered Surface-Immobilized Enzyme that Retains High Levels of Catalytic Activity in Air.

scientific article

Evaluation of a symmetry-based strategy for assembling protein complexes ⬇️

scientific article published on October 21, 2011

Evidence for a 1,3-Dipolar Cyclo-addition Mechanism in the Decarboxylation of Phenylacrylic Acids Catalyzed by Ferulic Acid Decarboxylase.

scientific article published on 28 July 2017

Extending fluorescence microscopy into anaerobic environments

scientific article published on 26 June 2019

Fluorinated proteins: from design and synthesis to structure and stability.

scientific article

Fluorine--a new element in the design of membrane-active peptides.

scientific article published on 28 July 2009

Fluorine: A new element in protein design ⬇️

scientific article published on February 14, 2012

Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site

scientific article published on 13 October 2020

High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification

scientific article published on 3 July 2015

How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum ⬇️

scientific article published on August 15, 1998

How enzymes control the reactivity of adenosylcobalamin: effect on coenzyme binding and catalysis of mutations in the conserved histidine-aspartate pair of glutamate mutase

scientific article published on 01 June 1997

Hydrogen tunneling in adenosylcobalamin-dependent glutamate mutase: evidence from intrinsic kinetic isotope effects measured by intramolecular competition.

scientific article

Imaging living obligate anaerobic bacteria with bilin-binding fluorescent proteins

scientific article published on 11 May 2020

Immobilized enzymes: understanding enzyme - surface interactions at the molecular level.

scientific article

Influence of fluorination on the thermodynamics of protein folding

scientific article published on 30 July 2012

Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound

scientific article

Insights into the mechanisms of adenosylcobalamin (coenzyme B12)-dependent enzymes from rapid chemical quench experiments.

scientific article published on April 2009

Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation

scientific article published on 30 January 2020

Intrinsic deuterium kinetic isotope effects in glutamate mutase measured by an intramolecular competition experiment.

scientific article published in January 2007

Investigating the Effect of Two-point Surface Attachment on Enzyme Stability and Activity

scientific article published on 19 November 2018

Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase.

scientific article published on 3 February 2015

Isotope effects for deuterium transfer between substrate and coenzyme in adenosylcobalamin-dependent glutamate mutase.

scientific article published in February 2005

Kinetic Analysis of Transient Intermediates in the Mechanism of Prenyl-Flavin-Dependent Ferulic Acid Decarboxylase

scientific article published on 19 December 2020

Kinetic Characterization of Prenyl-Flavin Synthase from Saccharomyces cerevisiae.

scientific article published on 12 December 2017

Mechanism of benzylsuccinate synthase probed by substrate and isotope exchange.

scientific article published on December 2006

Mechanism of benzylsuccinate synthase: stereochemistry of toluene addition to fumarate and maleate.

scientific article published in June 2005

Mechanistic insights from reaction of α-oxiranyl-aldehydes with cyanobacterial aldehyde deformylating oxygenase

scientific article published on 13 December 2013

Metal-dependent assembly of a protein nano-cage

scientific article published on 06 August 2019

Modulating protein structure with fluorous amino acids: increased stability and native-like structure conferred on a 4-helix bundle protein by hexafluoroleucine.

scientific article

Molecular Mechanisms of Interactions between Monolayered Transition Metal Dichalcogenides and Biological Molecules

scientific article published on 14 June 2019

Molecular orientation of enzymes attached to surfaces through defined chemical linkages at the solid-liquid interface.

scientific article published on 15 August 2013

Molecular-Level Insights into Orientation-Dependent Changes in the Thermal Stability of Enzymes Covalently Immobilized on Surfaces.

scientific article published on 27 May 2015

Oxygen‐Independent Decarbonylation of Aldehydes by Cyanobacterial Aldehyde Decarbonylase: A New Reaction of Diiron Enzymes ⬇️

scientific article published on June 10, 2011

Perfluoro-tert-butyl-homoserine as a sensitive 19F NMR reporter for peptide-membrane interactions in solution.

scientific article

Photolysis and recombination of adenosylcobalamin bound to glutamate mutase.

scientific article published in February 2004

Pre-steady-state kinetic investigation of intermediates in the reaction catalyzed by adenosylcobalamin-dependent glutamate mutase

scientific article published on 01 October 1999

Pre-steady-state measurement of intrinsic secondary tritium isotope effects associated with the homolysis of adenosylcobalamin and the formation of 5'-deoxyadensosine in glutamate mutase.

scientific article published in March 2004

Probing the Mechanism of Cyanobacterial Aldehyde Decarbonylase Using a Cyclopropyl Aldehyde ⬇️

scientific article published on April 2, 2013

Protein-coenzyme interactions in adenosylcobalamin-dependent glutamate mutase

scientific article

Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate.

scientific article published on September 2006

Recent advances in radical SAM enzymology: new structures and mechanisms.

scientific article

Role of Arg100 in the active site of adenosylcobalamin-dependent glutamate mutase.

scientific article published in March 2004

Role of active site residues in promoting cobalt-carbon bond homolysis in adenosylcobalamin-dependent mutases revealed through experiment and computation

scientific article published on 20 December 2013

Role of zinc in human islet amyloid polypeptide aggregation.

scientific article published on July 2010

Simultaneous Observation of the Orientation and Activity of Surface-Immobilized Enzymes

scientific article published on 24 July 2018

Solvent isotope effects on alkane formation by cyanobacterial aldehyde deformylating oxygenase and their mechanistic implications

scientific article

Structural basis for the enhanced stability of highly fluorinated proteins

scientific article

Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity

scientific article

Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein.

scientific article published on 27 January 2016

Substrate-bound structures of benzylsuccinate synthase reveal how toluene is activated in anaerobic hydrocarbon degradation.

scientific article

Surface Orientation Control of Site-Specifically Immobilized Nitro-reductase (NfsB)

scientific article published on 14 May 2014

Symmetry-Directed Self-Assembly of a Tetrahedral Protein Cage Mediated by de Novo-Designed Coiled Coils.

scientific article published in August 2017

Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex

scientific article published on 24 January 2020

The B(12)-binding subunit of glutamate mutase from Clostridium tetanomorphum traps the nucleotide moiety of coenzyme B(12)

scientific article published in June 2001

The Photoactive Excited State of the B12-Based Photoreceptor CarH

scientific article published on 11 November 2020

The fluorous effect in proteins: properties of alpha4F6, a 4-alpha-helix bundle protein with a fluorocarbon core.

scientific article

The reaction of the substrate analog 2-ketoglutarate with adenosylcobalamin-dependent glutamate mutase

scientific article published on 01 April 1999

The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase.

scientific article published in December 2001

The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.

scientific article

Time-Resolved Measurements of the Photolysis and Recombination of Adenosylcobalamin Bound to Glutamate Mutase

scientific article published on 01 September 2005

Toward an improved understanding of the glutamate mutase system

scientific article published on 24 January 2007

Tritium Partitioning and Isotope Effects in Adenosylcobalamin-Dependent Glutamate Mutase ⬇️

scientific article published on October 30, 2001

Tritium isotope effects in adenosylcobalamin-dependent glutamate mutase: implications for the mechanism

scientific article published on 01 June 1995

Using (19)F NMR to probe biological interactions of proteins and peptides

scientific article published on 06 May 2014

Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide

scientific article published on 01 February 2008

Using fluorine nuclear magnetic resonance to probe changes in the structure and dynamics of membrane-active peptides interacting with lipid bilayers.

scientific article

Using fluorine nuclear magnetic resonance to probe the interaction of membrane-active peptides with the lipid bilayer.

scientific article published in July 2010

Using fluorous amino acids to probe the effects of changing hydrophobicity on the physical and biological properties of the beta-hairpin antimicrobial peptide protegrin-1.

scientific article

Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils

scientific article published on 01 April 2006

Viperin interacts with the kinase IRAK1 and the E3 ubiquitin ligase TRAF6, coupling innate immune signaling to antiviral ribonucleotide synthesis

scientific article published on 14 March 2019

Viperin: an ancient radical-SAM enzyme finds its place in modern cellular metabolism and innate immunity

scientific article published on 16 June 2020

Viperin—taken down with a pinch of salt

scientific article published on 19 November 2021

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