List of works - Mikaela Grönholm

A functional association between merlin and HEI10, a cell cycle regulator.

scientific article

A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

scientific article published on 13 November 2018

A novel MLL-AF10 fusion mRNA variant in a patient with acute myeloid leukemia detected by a new asymmetric reverse transcription PCR method.

scientific article published in September 1997

Abnormal actin binding of aberrant β-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap myopathy

scientific article

Actin-organising properties of the muscular dystrophy protein myotilin

scientific article

Bioadhesive supramolecular hydrogel from unprotected, short d,l-peptides with Phe-Phe and Leu-Asp-Val motifs

scientific article published on 01 March 2020

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

scientific article

Characterization of human palladin, a microfilament-associated protein

scientific article

Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system

scientific journal article

Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization

scientific article (publication date: 30 April 2004)

Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity

scientific article published on September 2012

HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation

scientific article published on 9 September 2016

Isolation and characterization of platelet-derived extracellular vesicles

scientific article

K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity

scientific article

LFA-1 integrin antibodies inhibit leukocyte α4β1-mediated adhesion by intracellular signaling.

scientific article published on 21 July 2016

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

scientific article published in August 2003

Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies

scientific article (publication date: July 2014)

Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy

scientific article

Nebulin interactions with actin and tropomyosin are altered by disease-causing mutations.

scientific article

Phosphorylation of the α-chain in the integrin LFA-1 enables β2-chain phosphorylation and α-actinin binding required for cell adhesion

scientific article published in Journal of Biological Chemistry

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton

scientific article published on 10 December 2007

Regulation of integrin activity and signalling

scientific article published on 14 March 2009

Regulation of integrin activity by phosphorylation

scientific article published on January 2014

Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.

scientific article published on 2 October 2014

TCR-induced activation of LFA-1 involves signaling through Tiam1.

scientific article published on 29 August 2011

List of works by Mikaela Grönholm

A functional association between merlin and HEI10, a cell cycle regulator.

A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

A novel MLL-AF10 fusion mRNA variant in a patient with acute myeloid leukemia detected by a new asymmetric reverse transcription PCR method.

Abnormal actin binding of aberrant β-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap myopathy

Actin-organising properties of the muscular dystrophy protein myotilin

Bioadhesive supramolecular hydrogel from unprotected, short d,l-peptides with Phe-Phe and Leu-Asp-Val motifs

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

Characterization of human palladin, a microfilament-associated protein

Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system

Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization

Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity

HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation

Isolation and characterization of platelet-derived extracellular vesicles

K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity

LFA-1 integrin antibodies inhibit leukocyte α4β1-mediated adhesion by intracellular signaling.

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies

Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy

Nebulin interactions with actin and tropomyosin are altered by disease-causing mutations.

Phosphorylation of the α-chain in the integrin LFA-1 enables β2-chain phosphorylation and α-actinin binding required for cell adhesion

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton

Regulation of integrin activity and signalling

Regulation of integrin activity by phosphorylation

Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.

TCR-induced activation of LFA-1 involves signaling through Tiam1.