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List of works by Jens U Marquardt

Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

scientific article published on 15 March 2017

An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer

scientific article

Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.

scientific article

Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification

scientific article published on 14 December 2018

CD44 (Cluster of differentiation 44) promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin

scientific article published on 11 June 2020

Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis

scientific article published on 21 September 2018

Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis

scientific article published on 24 October 2017

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

scientific article

Context-Dependent Role of NF-κB Signaling in Primary Liver Cancer-from Tumor Development to Therapeutic Implications

scientific article published on 25 July 2019

Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells

scientific article

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

scientific article

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.

scientific article published on 20 November 2017

DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration.

scientific article published on 21 March 2016

Deconvolution of the cellular origin in hepatocellular carcinoma: Hepatocytes take the center stage

scientific article published on 27 July 2016

Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma

scientific article

Epigenetic reprogramming modulates malignant properties of human liver cancer.

scientific article

Functional and genetic deconstruction of the cellular origin in liver cancer.

scientific article

Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver

scientific article published in PLoS ONE

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

scientific article published in April 2012

High-definition endoscopy with iScan and Lugol's solution for the detection of inflammation in patients with nonerosive reflux disease: histologic evaluation in comparison with a control group.

scientific article published on 17 December 2014

Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.

scientific article

IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma.

scientific article published on 10 September 2012

Immunotherapy of Hepatocellular Carcinoma.

scientific article

Impact of Individual Components of the Metabolic Syndrome on the Outcome of Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib

scientific article published on 4 July 2017

Improved Prediction of Survival by a Risk Factor-Integrating Inflammatory Score in Sorafenib-Treated Hepatocellular Carcinoma

scientific article published on 04 October 2018

Inclusion of targeted therapies in the standard of care for metastatic colorectal cancer patients in a German cancer center: the more the better?!

scientific article published on 19 September 2014

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

scientific article published on 16 March 2015

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

scientific article

Linking MLL and the HGF-MET signaling pathway in liver cancer

scientific article published on 24 June 2013

Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways ⬇️

scientific article published on February 22, 2012

Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice

scientific article

Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress.

scientific article published on 06 July 2016

Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.

scientific article published on 18 December 2017

MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.

scientific article

MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

scientific article published in 2022

Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML.

scientific article published on 18 April 2017

Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types.

scientific article published on 19 March 2013

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies.

scientific article published on 23 July 2011

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer and

scientific article published on 05 February 2019

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis

scientific article published on 13 February 2020

Neighbor of Punc E11, a novel oncofetal marker for hepatocellular carcinoma.

scientific article

Next-generation genomic profiling of hepatocellular adenomas: a new era of individualized patient care.

scientific article

Next-generation sequencing: application in liver cancer-past, present and future?

scientific article published on August 2012

Obere gastrointestinale Blutung mit hämorrhagischem Schock am Ende einer Urlaubsreise: Präklinische und innerklinische Versorgung eines gastrointestinalen Notfalls

scientific article published on 13 May 2014

Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

scientific article published on 04 February 2016

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

scientific article published on 04 June 2018

Pulmonary resection for metastatic gastric cancer

scientific article published on 01 November 2010

RNA-Seq Atlas--a reference database for gene expression profiling in normal tissue by next-generation sequencing.

scientific article

Recipient liver function before liver transplantation influences post-transplantation survival in patients with HCC

scientific article published on 30 May 2018

Recombinant human hepatocyte growth factor provides protective effects in celurein-induced acute pancreatitis in mice.

scientific article published on 17 January 2018

Regulation of microRNAs and their role in liver development, regeneration and disease.

scientific article published on 13 April 2014

Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits.

scientific article published on 26 October 2013

SnapShot: Hepatocellular carcinoma

scientific article published on 01 April 2014

Snapshot liver transcriptome in hepatocellular carcinoma

scientific article published on 13 December 2011

Stem cells in hepatocarcinogenesis: evidence from genomic data

scientific article

Surveillance of Hepatocellular Carcinoma and Diagnostic Algorithms in Patients with Liver Cirrhosis

scientific article

The Role of Transforming Growth Factor-β in Human Hepatocarcinogenesis: Mechanistic and Therapeutic Implications From an Integrative Multiomics Approach.

scientific article published on 21 November 2017

The functional cancer map: a systems-level synopsis of genetic deregulation in cancer

scientific article

The immune contexture of hepatocellular carcinoma predicts clinical outcome.

scientific article published on 29 March 2018

The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib.

scientific article published on 21 November 2012

The role of molecular enrichment on future therapies in hepatocellular carcinoma

scientific article published on 2 March 2018

Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease.

scientific article published on 20 June 2017

Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis

scientific article

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

scientific article published on April 2015

Use of inhibitors of the renin-angiotensin system is associated with longer survival in patients with hepatocellular carcinoma

scientific article published on 26 February 2017

Validation of the simplified Animal Naming Test as primary screening tool for the diagnosis of covert hepatic encephalopathy

scientific article published on 19 August 2018

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells

scientific article published on 01 April 2019

[Etiology and complications of liver cirrhosis: data from a German centre].

scientific article

[Hepatocellular carcinoma: molecular pathogenesis and novel targets for therapy]

scientific article published on 11 April 2012

[Hepatocellular carcinoma: what's new?]

scientific article published on 16 January 2012

[Hepatocellular carcinoma]

scientific article published on 01 May 2017

[Personalised hepatology - current concepts, developments and expectations in the post-genome era]

scientific article published on 05 January 2012

[Response to Terlipressin and albumin is associated with improved outcome in patients with cirrhosis and hepatorenal syndrome]

scientific article published on 22 January 2015

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