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List of works by Sarah Cianférani

(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity

scientific article published on 21 February 2020

A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

scientific article published on 19 August 2019

A combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages

scientific article published on 19 December 2015

A novel online four-dimensional SECxSEC-IMxMS methodology for characterization of monoclonal antibody size variants

scientific article published on 12 November 2018

An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates.

scientific article published on 20 December 2017

Benchmarking quantitative label-free LC-MS data processing workflows using a complex spiked proteomic standard dataset.

scientific article

Benchmarking sample preparation/digestion protocols reveals tube-gel being a fast and repeatable method for quantitative proteomics.

scientific article published on 17 October 2016

CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.

scientific article

Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.

scientific article

Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity

scientific article published on 24 April 2015

Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets

scientific article

Computational and Mass-Spectrometry-Based Workflow for the Discovery and Validation of Missing Human Proteins: Application to Chromosomes 2 and 14.

scientific article published on July 2015

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

scientific article published on February 2015

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

scientific article

Dual Data-Independent Acquisition Approach Combining Global HCP Profiling and Absolute Quantification of Key Impurities during Bioprocess Development.

scientific article published on 13 December 2017

Formation of Mono- and Polynuclear Luminescent Lanthanide Complexes based on the Coordination of Preorganized Phosphonated Pyridines

scientific article published on 10 May 2018

Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis

scientific article

Greatwall dephosphorylation and inactivation upon mitotic exit is triggered by PP1.

scientific article published on 18 February 2016

Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine Transglycosylase

scientific article published on 14 June 2018

Homogeneous antibody-drug conjugates: DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly

scientific article published on 01 January 2020

How Reversible Are the Effects of Fumed Silica on Macrophages? A Proteomics-Informed View

scientific article published on 29 September 2020

Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

scientific article published on 21 October 2014

Insights from native mass spectrometry and ion mobility-mass spectrometry for antibody and antibody-based product characterization.

scientific article published on 31 March 2016

Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective.

scientific article published on 8 April 2015

Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes.

scientific article published on 24 September 2015

Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.

scientific article published on 22 July 2016

MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation.

scientific article published on 3 September 2015

Maltaricin CPN, a new class IIa bacteriocin produced by Carnobacterium maltaromaticum CPN isolated from mould-ripened cheese

scientific article published on 4 August 2016

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state

scientific article published on 11 August 2016

Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: A proteomic view

scientific article published on 11 August 2015

Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies

scientific article published on 16 July 2018

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate

scientific article

Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

scientific article published on 04 October 2020

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.

scientific article

Probing Supramolecular Interactions between a Crown Ether-Appended Zinc Phthalocyanine and an Ammonium Group Appended to a C60 Derivative

scientific article published on 7 January 2016

Quantitative analysis of hIgG1 in monkey serum by LC-MS/MS using mass spectrometric immunoassay

scientific article published on 20 April 2016

SMART Digest™ compared with pellet digestion for analysis of human immunoglobulin G1 in rat serum by liquid chromatography tandem mass spectrometry.

scientific article

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.

scientific article published on 13 December 2017

Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly

scientific article

Supramolecular luminescent lanthanide dimers for fluoride sequestering and sensing

scientific article

Swapping Interface Contacts in the Homodimeric tRNA-Guanine Transglycosylase: An Option for Functional Regulation

scientific article published on 16 July 2018

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL

scientific article

Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia

scientific article published on 08 April 2021

The H2O2-Resistant Fe–S Redox Switch MitoNEET Acts as a pH Sensor To Repair Stress-Damaged Fe–S Protein

scientific article published on 11 September 2018

The Importance of Charge in Perturbing the Aromatic Glue Stabilizing the Protein-Protein Interface of Homodimeric tRNA-Guanine Transglycosylase

scientific article published on 09 November 2020

The flexibility of a generic LC-MS/MS method for the quantitative analysis of therapeutic proteins based on human immunoglobulin G and related constructs in animal studies

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The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry.

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Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation

scientific article published on 26 September 2013

Towards integrative structural mass spectrometry: Benefits from hybrid approaches.

scientific article published on 29 May 2015

What Glues a Homodimer Together: Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme Tgt

scientific article

p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions

scientific article published on 01 March 2013