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List of works by Yutaka Yoshikawa

A [meso-tetrakis(4-sulfonatophenyl)porphyrinato]zinc(ii) complex as an oral therapeutic for the treatment of type 2 diabetic KKA(y) mice

scientific article published on 01 February 2007

A family of insulinomimetic zinc(II) complexes of amino ligands with Zn(Nn) (n=3 and 4) coordination modes.

scientific article published in July 2005

A new type of orally active anti-diabetic Zn(II)-dithiocarbamate complex

scientific article published on 10 November 2006

A novel drug delivery system for type 1 diabetes: insulin-mimetic vanadyl-poly(gamma-glutamic acid) complex.

scientific article published on 24 May 2006

Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes.

scientific article published on 23 October 2015

Alpha-glucosidase inhibitory effect of anti-diabetic metal ions and their complexes.

scientific article

Amelioration of hyperglycemia and metabolic syndromes in type 2 diabetic KKA(y) mice by poly(gamma-glutamic acid)oxovanadium(IV) complex

scientific article published on 01 November 2007

Aminoacid-derivatised picolinato-oxidovanadium(IV) complexes: characterisation, speciation and ex vivo insulin-mimetic potential

scientific article

Anti-Diabetic Effect of Organo-Chalcogen (Sulfur and Selenium) Zinc Complexes with Hydroxy-Pyrone Derivatives on Leptin-Deficient Type 2 Diabetes Model ob/ob Mice

scientific article

Anti-diabetes effect of Zn(II)/carnitine complex by oral administration.

scientific article

Anti-hyperglycemic Effect of Long-Term Bis(hinokitiolato)zinc Complex ([Zn(hkt)2]) Ingestion on Insulin Resistance and Pancreatic Islet Cells Protection in Type 2 Diabetic KK-Ay Mice.

scientific article published in January 2017

Antidiabetic copper(II)-picolinate: impact of the first transition metal in the metallopicolinate complexes

scientific article published on 05 May 2007

Antidiabetic effect of the α-lipoic acid γ-cyclodextrin complex.

scientific article published on September 2014

Antidiabetic zinc(II)-N-acetyl-L-cysteine complex: evaluations of in vitro insulinomimetic and in vivo blood glucose-lowering activities.

scientific article published in January 2007

Beneficial Effect of Bis(Hinokitiolato)Zn Complex on High-fat Diet-induced Lipid Accumulation in Mouse Liver and Kidney

scientific article published in November 2017

Bis (aspirinato) zinc (II) complex successfully inhibits carotid arterial neointima formation after balloon-injury in rats

scientific article published on 01 December 2014

Bis(6-ethylpicolinato)oxovanadium(IV) complex with normoglycemic activity in KK-Ay mice ⬇️

scientific article published on January 1, 2002

Bis(hinokitiolato)zinc complex ([Zn(hkt)2]) activates Akt/protein kinase B independent of insulin signal transduction

scientific article

Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential

scientific article published on 5 August 2009

Challenge of studies on the development of new Zn complexes (Zn(opt)₂) to treat diabetes mellitus

scientific article published on 17 May 2011

Development of a novel antidiabetic zinc complex with an organoselenium ligand at the lowest dosage in KK-A(y) mice.

scientific article published on 23 December 2012

Development of new zinc dithiosemicarbazone complex for use as oral antidiabetic agent.

scientific article

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

scientific article (publication date: 6 December 2011)

Dietary α-cyclodextrin modifies gut microbiota and reduces fat accumulation in high-fat-diet-fed obese mice

scientific article published on 07 May 2018

Effects of Zn(II) complex with vitamins C and U, and carnitine on metabolic syndrome model rats

scientific article published on 24 June 2011

Feasibility of structural modification of retinoid X receptor agonists to separate blood glucose-lowering action from adverse effects: studies in KKA(y) type 2 diabetes model mice

scientific article published on 01 January 2012

Improvement of diabetes, obesity and hypertension in type 2 diabetic KKAy mice by bis(allixinato)oxovanadium(IV) complex

scientific article published on 08 May 2006

Improvement of hyperglycaemia and metabolic syndromes in type 2 diabetic KKAy mice by oral treatment with [meso-tetrakis(4-sulfonatophenyl) porphyrinato]oxovanadium(IV)(4-) complex

scientific article published on 01 March 2007

In vitro study on the transport of zinc across intestinal epithelial cells using Caco-2 monolayers and isolated rat intestinal membranes

scientific article published on 01 January 2012

Insulinomimetic bis(maltolato)zinc(II) complex: blood glucose normalizing effect in KK-A(y) mice with type 2 diabetes mellitus.

scientific article

Investigating the target organs of novel anti-diabetic zinc complexes with organo‑selenium ligands

scientific article published on 12 May 2018

Investigation of Biodistribution and Speciation Changes of Orally Administered Dual Radiolabeled Complex, Bis(5-chloro-7-[131I]iodo-8-quinolinolato)[65Zn]zinc.

scientific article published in January 2017

Investigation of the insulin-like properties of zinc(II) complexes of 3-hydroxy-4-pyridinones: Identification of a compound with glucose lowering effect in STZ-induced type I diabetic animals

scientific article published on 10 September 2011

Isomeric effects of anti-diabetic α-lipoic acid with γ-cyclodextrin.

scientific article published on 2 July 2015

Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid and structural development to increase potency.

scientific article published on 20 February 2013

Metallokinetic study of zinc in the blood of normal rats given insulinomimetic zinc(II) complexes and improvement of diabetes mellitus in type 2 diabetic GK rats by their oral administration.

scientific article published in January 2002

Morphological analysis of the pancreas and liver in diabetic KK-A(y) mice treated with zinc and oxovanadium complexes

scientific article published on 01 September 2014

Novel 3-hydroxy-4-pyridinonato oxidovanadium(IV) complexes to investigate structure/activity relationships

scientific article published on 18 January 2009

Oral administration of Bis(aspirinato)zinc(II) complex ameliorates hyperglycemia and metabolic syndrome-like disorders in spontaneously diabetic KK-A(y) mice: structure-activity relationship on zinc-salicylate complexes

scientific article published on 01 January 2011

Oral administration of a zinc complex improves type 2 diabetes and metabolic syndromes

scientific article published on 11 October 2006

Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway

scientific article published on 6 May 2016

Organ distribution of quantum dots after intraperitoneal administration, with special reference to area-specific distribution in the brain

scientific article

Pharmacological and pharmacokinetic studies of anti-diabetic tropolonato-Zn(II) complexes with Zn(S(2)O(2)) coordination mode

scientific article published on 01 January 2012

Possible mode of action for insulinomimetic activity of vanadyl(IV) compounds in adipocytes.

scientific article

Potential insulinominetic agents of zinc(II) complexes with picolinamide derivatives: preparations of complexes, in vitro and in vivo studies.

scientific article published in March 2002

RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists.

scientific article

Structural and redox requirements for the action of anti-diabetic vanadium compounds

scientific article published on 25 March 2014

Superiority of zinc complex of acetylsalicylic acid to acetylsalicylic acid in preventing postischemic myocardial dysfunction.

scientific article published on 09 February 2015

Synthesis and in vitro insulin-mimetic activities of zinc(ii) complexes of ethyl 2,5-dihydro-4-hydroxy-5-oxo-1H-pyrrole-3-carboxylates

scientific article published on 18 March 2011

Synthesis, structure analysis, solution chemistry, and in vitro insulinomimetic activity of novel oxovanadium(IV) complexes with tripodal ligands containing an imidazole group derived from amino acids.

scientific article

Testicular Mineralization in KK-A(y) Mice Treated with an Oxovanadium Complex.

scientific article published on September 2013

Transient elevation of serum cystatin C concentrations during perioperative cisplatin-based chemotherapy in esophageal cancer patients.

scientific article published on 22 March 2012

Visualization of biodistribution of Zn complex with antidiabetic activity using semiconductor Compton camera GREI

scientific article published on 8 December 2015

Zinc Complexes Developed as Metallopharmaceutics for Treating Diabetes Mellitus based on the Bio-Medicinal Inorganic Chemistry ⬇️

scientific article published on January 1, 2012

[Challenge of studies on the development of new Zn complexes to treat diabetes mellitus]

scientific article published on 01 January 2011

[Challenging the development of new anti-diabetic medicine--approaching from educational, clinical, and research fields]

scientific article published on 01 January 2011

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