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List of works by Mattia Volta

A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics

scientific article published on 02 August 2018

Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.

scientific article

Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging

scientific article published in January 2014

CADPS2 gene expression is oppositely regulated by LRRK2 and alpha-synuclein.

scientific article

Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release

scientific article published on August 2015

DNAJC13 mutations in Parkinson disease

scientific article (publication date: April 2014)

Dopamine–nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity

scientific article published on 06 January 2011

Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

scientific article published on 18 November 2016

Further evidence for an involvement of nociceptin/orphanin FQ in the pathophysiology of Parkinson’s disease: a behavioral and neurochemical study in reserpinized mice ⬇️

scientific article published on November 11, 2010

Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice

scientific article published on 20 September 2017

Insights from late-onset familial parkinsonism on the pathogenesis of idiopathic Parkinson's disease

scientific article published on October 2015

Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions

scientific article published on 08 June 2020

LRRK2 mouse models: dissecting the behavior, striatal neurochemistry and neurophysiology of PD pathogenesis

scientific article published on February 2017

LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory

scientific article

Memory and synaptic deficits in Hip14/DHHC17 knockout mice.

scientific article

Nanoparticulate lipid dispersions for bromocriptine delivery: characterization and in vivo study

scientific article published on 28 October 2011

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.

scientific article published on 21 November 2014

Stimulation of delta opioid receptors located in substantia nigra reticulata but not globus pallidus or striatum restores motor activity in 6-hydroxydopamine lesioned rats: new insights into the role of delta receptors in parkinsonism

scientific article

Stimulation of δ opioid receptor and blockade of nociceptin/orphanin FQ receptor synergistically attenuate parkinsonism.

scientific article published in September 2014

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice.

scientific article published on 26 September 2014

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