List of works - Michal Mokry

A systematic analysis of genetic dilated cardiomyopathy reveals numerous ubiquitously expressed and muscle-specific genes

scientific article

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

scientific article

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

scientific article

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function

scientific article

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

scientific article published on August 2016

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts

scientific article

Autoimmune disease-associated gene expression is reduced by BET-inhibition

scientific article published on 7 November 2015

Canonical Wnt signaling negatively modulates regulatory T cell function.

scientific article published on 15 August 2013

Chemokines as possible targets in modulation of the secondary damage after acute spinal cord injury: a review.

scientific article published on 11 April 2009

Chromatin Conformation Links Distal Target Genes to CKD Loci

scientific article

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

scientific article published on 5 March 2010

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

scientific journal article

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

scientific journal article

E2f8 mediates tumor suppression in postnatal liver development

scientific article published on 25 July 2016

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles

scientific article

Enhancers reside in a unique epigenetic environment during early zebrafish development

scientific article published on 5 July 2016

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

scientific article published on October 2017

Epigenetic modification of the oxytocin and glucocorticoid receptor genes is linked to attachment avoidance in young adults

scientific article published on 7 March 2018

Extensive Association of Common Disease Variants with Regulatory Sequence.

scientific article published on 22 November 2016

FOXO3 selectively amplifies enhancer activity to establish target gene regulation

scientific article published on 19 December 2013

FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis

scientific article published on 5 July 2013

FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells

scientific article

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2.

scientific article published on 21 December 2015

Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid

scientific article published on 23 January 2016

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

scientific article published on January 2013

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

scientific article published on 17 December 2015

Genomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitations

scientific article

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

H3K27 acetylation and gene expression analysis reveals differences in placental chromatin activity in fetal growth restriction.

scientific article

Histological assessment of the effect of laser irradiation on skin wound healing in rats.

scientific article published in August 2006

Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy

scientific article

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach

scientific article

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression

scientific article published on 15 September 2015

Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes

scientific article published on 13 September 2011

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

scientific article

Intracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis

scientific article published on 4 January 2018

Major and minor group rhinoviruses elicit differential signaling and cytokine responses as a function of receptor-mediated signal transduction

scientific article

Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

scientific article published on 12 December 2013

Megakaryocyte lineage development is controlled by modulation of protein acetylation

scientific article published on 26 April 2018

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

scientific article published on 23 March 2021

Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing

scientific article

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples

scientific article published on 17 October 2010

Neonatal thymectomy reveals differentiation and plasticity within human naive T cells

scientific article published on 22 February 2016

Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade

scientific article published on 9 February 2018

Non-coding DNA in IBD: from sequence variation in DNA regulatory elements to novel therapeutic potential

scientific article published on 28 January 2019

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

scientific article published on 02 August 2018

Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment

scientific article published on 15 December 2011

Prime editing for functional repair in patient-derived disease models

scientific article published on 23 October 2020

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

scientific article published on 12 January 2021

Simple method of open skin wound healing model in corticosteroid-treated and diabetic rats: standardization of semi-quantitative and quantitative histological assessments

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles.

scientific article published on 6 June 2018

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

scientific article published on 30 November 2016

Systematic biases in DNA copy number originate from isolation procedures

scientific article

The Atp1a1 gene from inbred Dahl salt sensitive rats does not contain the A1079T missense transversion

scientific article

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

scientific article published on 19 August 2015

Tissue-specific mutation accumulation in human adult stem cells during life

scientific article published on 3 October 2016

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

scholarly article by J G C Peeters et al published January 2019 in Autophagy

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.

scientific article published on 10 January 2014

List of works by Michal Mokry

A systematic analysis of genetic dilated cardiomyopathy reveals numerous ubiquitously expressed and muscle-specific genes

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts

Autoimmune disease-associated gene expression is reduced by BET-inhibition

Canonical Wnt signaling negatively modulates regulatory T cell function.

Chemokines as possible targets in modulation of the secondary damage after acute spinal cord injury: a review.

Chromatin Conformation Links Distal Target Genes to CKD Loci

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

E2f8 mediates tumor suppression in postnatal liver development

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles

Enhancers reside in a unique epigenetic environment during early zebrafish development

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

Epigenetic modification of the oxytocin and glucocorticoid receptor genes is linked to attachment avoidance in young adults

Extensive Association of Common Disease Variants with Regulatory Sequence.

FOXO3 selectively amplifies enhancer activity to establish target gene regulation

FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis

FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2.

Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

Genomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitations

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

H3K27 acetylation and gene expression analysis reveals differences in placental chromatin activity in fetal growth restriction.

Histological assessment of the effect of laser irradiation on skin wound healing in rats.

Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression

Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Intracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis

Major and minor group rhinoviruses elicit differential signaling and cytokine responses as a function of receptor-mediated signal transduction

Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

Megakaryocyte lineage development is controlled by modulation of protein acetylation

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples

Neonatal thymectomy reveals differentiation and plasticity within human naive T cells

Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade

Non-coding DNA in IBD: from sequence variation in DNA regulatory elements to novel therapeutic potential

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment

Prime editing for functional repair in patient-derived disease models

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

Simple method of open skin wound healing model in corticosteroid-treated and diabetic rats: standardization of semi-quantitative and quantitative histological assessments

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles.

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

Systematic biases in DNA copy number originate from isolation procedures

The Atp1a1 gene from inbred Dahl salt sensitive rats does not contain the A1079T missense transversion

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Tissue-specific mutation accumulation in human adult stem cells during life

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.