List of works - Daniel Konrad

10-day hyperlipidemic clamp in cats: effects on insulin sensitivity, inflammation, and glucose metabolism-related genes.

scientific article published on 16 February 2010

A novel DAX-1 (NR0B1) mutation in a boy with X-linked adrenal hypoplasia congenita

scientific article published on 31 October 2017

A novel GATA6 variant in a boy with neonatal diabetes and diaphragmatic hernia: a familial case with a review of the literature

scientific article published on 01 September 2019

A short bout of HFD promotes long-lasting hepatic lipid accumulation.

scientific article published on 17 July 2015

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

scientific article

ASK1 inhibits browning of white adipose tissue in obesity

scientific article published on 02 April 2020

Adipocyte-specific gp130 signalling mediates exercise-induced weight reduction

scientific article published on 29 August 2019

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

scientific article published on 4 June 2013

Author Correction: Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease

scientific article published on 21 July 2020

Basal lipolysis, not the degree of insulin resistance, differentiates large from small isolated adipocytes in high-fat fed mice.

scientific article published on 2 December 2008

Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency.

scientific article

Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major

Characteristics of Growth in Children With Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency During Adrenarche and Beyond

scientific article published on 01 January 2022

Congenital Hypogonadotropic Hypogonadism and Constitutional Delay of Growth and Puberty Have Distinct Genetic Architectures

scientific article published in February 2018

Cushing syndrome after bilateral lensectomy

scientific article published on 24 December 2014

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

scientific article

Depletion of ASK1 blunts stress-induced senescence in adipocytes

scientific article published on 01 December 2020

Depot-specific differences in adipocyte insulin sensitivity in mice are diet- and function-dependent.

scientific article published on July 2012

Determining Reference Ranges for Total T4 in Dried Blood Samples for Newborn Screening

scientific article published on 04 March 2020

Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency

scientific article

Double variants in TSHR and DUOX2 in a patient with hypothyroidism: case report

scientific article published on 01 November 2019

Early-Onset Complete Ovarian Failure and Lack of Puberty in a Woman With Mutated Estrogen Receptor β (ESR2)

scientific article published on 01 October 2018

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

scientific article published in January 2018

Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance

scientific article published on January 2014

Fas activates lipolysis in a Ca2+-CaMKII-dependent manner in 3T3-L1 adipocytes ⬇️

scientific article published on October 21, 2012

Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt.

scientific article published on 7 September 2010

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes

scientific article published on 20 December 2013

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

scientific article published on 7 September 2017

Future glycemic control of children diagnosed with type 1 diabetes mellitus at toddler and preschool/school age

scientific article published on 01 September 2019

Genotype-phenotype spectrum in isolated and syndromic nanophthalmos

scientific article published on 30 September 2020

Group G streptococcus sacroilitis with sepsis in a 15-y-old adolescent

scientific article published on 01 January 1999

IL-6-Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion

scientific article

Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and müllerian duct abnormalities: a French collaborative study

scientific article

Identification of a SIRT1 mutation in a family with type 1 diabetes

scientific article published on March 2013

Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue.

scientific article

Improved glycemic control and lower frequency of severe hypoglycemia with insulin detemir; long-term experience in 105 children and adolescents with type 1 diabetes.

scientific article published on 5 March 2008

In Memoriam: Ruth Illig, MD (1924-2017).

scientific article published in September 2017

Induction of cytosolic phospholipase a2α is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high-fat feeding.

scientific article published on 13 May 2013

Insulin-dependent diabetes mellitus induced by the antitussive agent dextromethorphan

scientific article published on 01 February 2000

Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation.

scientific article published on 21 July 2010

Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability

scientific article

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

scientific article published in November 2017

Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice

scientific article

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.

scientific article

Intermittent fasting improves metabolic flexibility in short-term high-fat diet-fed mice

scientific article published on 10 September 2019

Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice.

scientific article

Iron metabolism in patients with Graves' hyperthyroidism.

scientific article

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis

scientific article published on 06 June 2019

Mediators of Interorgan Crosstalk in Metabolic Inflammation.

scientific article

Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance

scientific article published on 17 September 2015

Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice

scientific article published in February 2016

Neurosonographic findings in premature infants and infants with intrauterine growth retardation with a birth weight below 1,500 grams

scientific article published on September 1, 1992

Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice

scientific article

Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene

scientific article

Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease

scientific article published on 29 April 2020

Penoscrotal hypospadias and coarctation of the aorta with mixed gonadal dysgenesis

scientific article published on 01 January 2000

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.

scientific article published on 16 January 2017

Pseudotumour cerebri after varicella

scientific article published on 01 November 1998

Response of interleukin-6 during euglycaemic and hyperglycaemic exercise in patients with type 1 diabetes mellitus.

scientific article published on 26 May 2010

Short-term HFD does not alter lipolytic function of adipocytes

scientific article published on 08 January 2014

Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than an obesogenic high-fat diet

scientific article published on 08 August 2018

Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas

scientific article published on 01 December 2003

Still too little, too late? Ten years of growth hormone therapy baseline data from the NordiNet® International Outcome Study

scientific article published on 01 April 2018

Ten-year follow-up in a boy with Leydig cell tumor after selective surgery

scientific article published on 01 January 1999

The Aldosterone/Renin Ratio as a Diagnostic Tool for the Diagnosis of Primary Hypoaldosteronism in Newborns and Infants.

scientific article published on 9 May 2015

The Fas pathway is involved in pancreatic beta cell secretory function

scholarly article

The Portal Theory Supported by Venous Drainage–Selective Fat Transplantation ⬇️

scientific article published on October 18, 2010

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

scientific article published on June 2001

The gut-adipose-liver axis in the metabolic syndrome

scientific article

The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release

scientific article published on 03 August 2018

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

scientific article published on 21 April 2010

Transient severe non-proliferative retinopathy in an adolescent with type 1 diabetes and chronic myeloid leukemia

scientific article published on 23 July 2012

Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells.

scientific article

Two Siblings with the Same Severe Form of 21-Hydroxylase Deficiency But Different Growth and Menstrual Cycle Patterns.

scientific article published on March 2017

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney

scientific article

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity

scientific article published on 26 June 2018

Visceral fat and metabolic inflammation: the portal theory revisited.

scientific article published on December 2012

WNT4 and sex development.

scientific article

WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report

scientific article

[Insufficient understanding of second tumors after childhood neoplasms in Switzerland]

scientific article published on 01 March 1998

List of works by Daniel Konrad

10-day hyperlipidemic clamp in cats: effects on insulin sensitivity, inflammation, and glucose metabolism-related genes.

A novel DAX-1 (NR0B1) mutation in a boy with X-linked adrenal hypoplasia congenita

A novel GATA6 variant in a boy with neonatal diabetes and diaphragmatic hernia: a familial case with a review of the literature

A short bout of HFD promotes long-lasting hepatic lipid accumulation.

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

ASK1 inhibits browning of white adipose tissue in obesity

Adipocyte-specific gp130 signalling mediates exercise-induced weight reduction

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Author Correction: Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease

Basal lipolysis, not the degree of insulin resistance, differentiates large from small isolated adipocytes in high-fat fed mice.

Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency.

Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major

Characteristics of Growth in Children With Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency During Adrenarche and Beyond

Congenital Hypogonadotropic Hypogonadism and Constitutional Delay of Growth and Puberty Have Distinct Genetic Architectures

Cushing syndrome after bilateral lensectomy

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

Depletion of ASK1 blunts stress-induced senescence in adipocytes

Depot-specific differences in adipocyte insulin sensitivity in mice are diet- and function-dependent.

Determining Reference Ranges for Total T4 in Dried Blood Samples for Newborn Screening

Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency

Double variants in TSHR and DUOX2 in a patient with hypothyroidism: case report

Early-Onset Complete Ovarian Failure and Lack of Puberty in a Woman With Mutated Estrogen Receptor β (ESR2)

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance

Fas activates lipolysis in a Ca2+-CaMKII-dependent manner in 3T3-L1 adipocytes ⬇️

Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt.

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Future glycemic control of children diagnosed with type 1 diabetes mellitus at toddler and preschool/school age

Genotype-phenotype spectrum in isolated and syndromic nanophthalmos

Group G streptococcus sacroilitis with sepsis in a 15-y-old adolescent

IL-6-Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion

Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and müllerian duct abnormalities: a French collaborative study

Identification of a SIRT1 mutation in a family with type 1 diabetes

Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue.

Improved glycemic control and lower frequency of severe hypoglycemia with insulin detemir; long-term experience in 105 children and adolescents with type 1 diabetes.

In Memoriam: Ruth Illig, MD (1924-2017).

Induction of cytosolic phospholipase a2α is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high-fat feeding.

Insulin-dependent diabetes mellitus induced by the antitussive agent dextromethorphan

Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation.

Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.

Intermittent fasting improves metabolic flexibility in short-term high-fat diet-fed mice

Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice.

Iron metabolism in patients with Graves' hyperthyroidism.

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis

Mediators of Interorgan Crosstalk in Metabolic Inflammation.

Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance

Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice

Neurosonographic findings in premature infants and infants with intrauterine growth retardation with a birth weight below 1,500 grams

Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice

Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene

Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease

Penoscrotal hypospadias and coarctation of the aorta with mixed gonadal dysgenesis

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.

Pseudotumour cerebri after varicella

Response of interleukin-6 during euglycaemic and hyperglycaemic exercise in patients with type 1 diabetes mellitus.

Short-term HFD does not alter lipolytic function of adipocytes

Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than an obesogenic high-fat diet

Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas

Still too little, too late? Ten years of growth hormone therapy baseline data from the NordiNet® International Outcome Study

Ten-year follow-up in a boy with Leydig cell tumor after selective surgery

The Aldosterone/Renin Ratio as a Diagnostic Tool for the Diagnosis of Primary Hypoaldosteronism in Newborns and Infants.

The Fas pathway is involved in pancreatic beta cell secretory function

The Portal Theory Supported by Venous Drainage–Selective Fat Transplantation ⬇️

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

The gut-adipose-liver axis in the metabolic syndrome

The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

Transient severe non-proliferative retinopathy in an adolescent with type 1 diabetes and chronic myeloid leukemia

Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells.

Two Siblings with the Same Severe Form of 21-Hydroxylase Deficiency But Different Growth and Menstrual Cycle Patterns.

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity

Visceral fat and metabolic inflammation: the portal theory revisited.

WNT4 and sex development.

WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report