List of works by Armelle Yart

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

scientific article

A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid.

scientific article published on 26 March 2002

An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.

scientific article

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

scientific article published on 01 December 2019

Functional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3beta signaling

scientific article

Gab1, SHP-2 and other novel regulators of Ras: targets for anticancer drug discovery?

scientific article

Growth patterns of patients with Noonan syndrome: correlation with age and genotype

scientific article

How do Shp2 mutations that oppositely influence its biochemical activity result in syndromes with overlapping symptoms?

scientific article

LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity

scientific article

Lysophospholipids and cancer: current status and perspectives

scientific article published in February 2005

Modulation of phosphoinositide 3-kinase activation by cholesterol level suggests a novel positive role for lipid rafts in lysophosphatidic acid signalling.

scientific article published in January 2003

New molecular mechanisms of growth hormone insensitivity

scientific article

Noonan syndrome males display Sertoli cell-specific primary testicular insufficiency

scientific article published on 01 December 2018

Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth

scientific article published on 01 July 2018

Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.

scientific article published on 27 February 2012

Noonan syndrome: an update on growth and development.

scientific article published on 7 November 2017

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor

scientific article published on 25 March 2022

Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.

scientific article

SHP2 sails from physiology to pathology.

scientific article published on 02 September 2015

Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition

scientific article published on 19 November 2007

Sporadic human renal tumors display frequent allelic imbalances and novel mutations of the HRPT2 gene

scientific article published on 27 November 2006

The Adaptor Protein Gab1 Couples the Stimulation of Vascular Endothelial Growth Factor Receptor-2 to the Activation of Phosphoinositide 3-Kinase

scientific article published in 2006

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II

scientific article

The RASopathy Family: Consequences of Germline Activation of the RAS/MAPK Pathway

scientific article published on 01 October 2018

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

scientific article published on 11 October 2007

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