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List of works by Giulio Kleiner

A serological assay to detect SARS-CoV-2 seroconversion in humans

scientific article published on 12 May 2020

Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition

scientific article published on 29 August 2019

Alendronate, a double-edged sword acting in the mevalonate pathway.

scientific article

Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion.

scientific article published on January 2011

Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.

scientific article published on 22 April 2014

Clinical genetic testing of periodic fever syndromes

scientific article

CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway

scientific article published on 06 September 2018

Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway.

scientific article

Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in Glioblastoma

scientific article published on 15 May 2018

Cytokine levels in the serum of healthy subjects

scientific article published on 7 March 2013

Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum

scientific article published on 27 May 2016

Farnesyl and geranylgeranyl transferase inhibitors: an anti-inflammatory effect. Comment to "Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells" Haematologica. 2

scientific article

Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma.

scientific article published on 9 May 2018

Introductions and early spread of SARS-CoV-2 in the New York City area

scientific article published on 29 May 2020

Lovastatin dose-dependently potentiates the pro-inflammatory activity of lipopolysaccharide both in vitro and in vivo

scientific article published on December 2013

Lovastatin induces apoptosis through the mitochondrial pathway in an undifferentiated SH-SY5Y neuroblastoma cell line

scientific article published on 11 April 2013

MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma

scientific article published on 06 November 2019

Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma

scientific article published on 23 July 2018

Mevalonate kinase deficiency and IBD: shared genetic background.

scientific article published on 14 February 2014

Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis

scientific article

Microglia activation and interaction with neuronal cells in a biochemical model of mevalonate kinase deficiency

scientific article published on August 2015

Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy

scientific article published on 18 October 2018

Mitochondrial dysfunction in fibroblasts of Multiple System Atrophy

scientific article published on 19 September 2018

Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients

scientific article published on 12 June 2013

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

scientific article published on 19 March 2015

Repositioning Of Tak-475 In Mevalonate Kinase Disease: Translating Theory Into Practice

scientific article published on 11 September 2017

Serum amyloid A and cholesterol: a pivotal role on inflammation

article published in 2012

Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study

scientific article

Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study

scientific article published on September 2013

The Role of Sulfide Oxidation Impairment in the Pathogenesis of Primary CoQ Deficiency

scientific article published on 25 July 2017