List of works - Annalisa Marcuzzi

A common genetic background could explain early-onset Crohn’s disease

scientific article published on 10 February 2012

A comparative analysis of serologic parameters and oxidative stress in osteoarthritis and rheumatoid arthritis: reply to Mishra and colleagues.

scientific article

Alendronate, a double-edged sword acting in the mevalonate pathway.

scientific article

Altered germinal center reaction and abnormal B cell peripheral maturation in PI3KR1-mutated patients presenting with HIGM-like phenotype.

scientific article

Autoinflammatory Diseases and Cytokine Storms—Imbalances of Innate and Adaptative Immunity

scientific article published in 2021

Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.

scientific article published on 22 April 2014

Clinical genetic testing of periodic fever syndromes

scientific article

Comments on ''Geranylgeraniol--a new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw" by Ziebart T et al. (2011)

scientific article published on 15 March 2011

Comments to the editor concerning the paper entitled "Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways" Shiekh Tanveer Ahmad et al

scientific article published on 23 December 2011

Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage.

scientific article

Curcumin and inflammatory bowel disease: potential and limits of innovative treatments.

scientific article

Cytokine levels in the serum of healthy subjects

scientific article published on 7 March 2013

Cytokine profiles of women with vulvodynia: Identification of a panel of pro-inflammatory molecular targets

scientific article published on 24 May 2018

Database tools in genetic diseases research ⬇️

scientific article published on November 10, 2012

Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.

scientific article published on September 2011

Ex vivo response to mucosal bacteria and muramyl dipeptide in inflammatory bowel disease

scientific article

Family history in early-onset inflammatory bowel disease

Farnesyl and geranylgeranyl transferase inhibitors: an anti-inflammatory effect. Comment to "Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells" Haematologica. 2

scientific article

Genetic and functional profiling of Crohn's disease: autophagy mechanism and susceptibility to infectious diseases

scientific article

Inflammation profile of four early onset Crohn patients

article

Inflammatory bowel disease and patterns of volatile organic compounds in the exhaled breath of children: A case-control study using Ion Molecule Reaction-Mass Spectrometry.

scientific article published on 31 August 2017

Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway

scientific article

Is autophagy an elective strategy to protect neurons from dysregulated cholesterol metabolism?

scientific article published on 01 April 2019

Letter to the Editor

scientific article published on 24 January 2012

Letter to the Editor: Acute Effects of Intravenous Administration of Pamidronate in Patients with Osteoporosis ⬇️

scientific article published on May 18, 2011

Letter: inflammatory bowel disease, complementary and alternative medicine, and genetics

article

Long Non-Coding RNA GAS5 and Intestinal MMP2 and MMP9 Expression: A Translational Study in Pediatric Patients with IBD

scientific article published on 24 October 2019

Lovastatin dose-dependently potentiates the pro-inflammatory activity of lipopolysaccharide both in vitro and in vivo

scientific article published on December 2013

Lovastatin induces apoptosis through the mitochondrial pathway in an undifferentiated SH-SY5Y neuroblastoma cell line

scientific article published on 11 April 2013

Lovastatin-induced apoptosis is modulated by geranylgeraniol in a neuroblastoma cell line

scientific article

Mevalonate kinase deficiency and IBD: shared genetic background.

scientific article published on 14 February 2014

Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis

scientific article

Mevalonate kinase deficiency: disclosing the role of mevalonate pathway modulation in inflammation

scientific article published on January 2012

Microglia activation and interaction with neuronal cells in a biochemical model of mevalonate kinase deficiency

scientific article published on August 2015

Monocyte-predominant engraftment, cytokine levels and early transplant-related complications in pediatric hematopoietic stem cell recipients

scientific article published on 28 January 2019

Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients

scientific article published on 12 June 2013

Neuronal Dysfunction Associated with Cholesterol Deregulation.

scientific article

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

scientific article published on 19 March 2015

Presence of IL-9 in Paired Samples of Human Colostrum and Transitional Milk

article by Annalisa Marcuzzi et al published 31 December 2012 in Journal of Human Lactation

Putative modifier genes in mevalonate kinase deficiency.

scientific article published on 22 February 2016

Serum amyloid A and cholesterol: a pivotal role on inflammation

article published in 2012

Specific protein profile in cerebrospinal fluid from HIV-1-positive cART-treated patients affected by neurological disorders

article

Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study

scientific article

TRAIL administration down-modulated the acute systemic inflammatory response induced in a mouse model by muramyldipeptide or lipopolysaccharide

scientific article published on 21 June 2012

Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.

scientific article published on 3 March 2010

Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study

scientific article published on September 2013

The Complex Interplay between Lipids, Immune System and Interleukins in Cardio-Metabolic Diseases ⬇️

scientific article published on 14 December 2018

The effect of clodronate on a mevalonate kinase deficiency cellular model

scientific article

The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.

scientific article published on July 2011

To Extinguish the Fire from Outside the Cell or to Shutdown the Gas Valve Inside? Novel Trends in Anti-Inflammatory Therapies

scientific article

Two‑gene mutation in a single patient: Biochemical and functional analysis for a correct interpretation of exome results

scientific article published on 11 August 2015

Type I interferon-mediated autoinflammation due to DNase II deficiency

scientific article published on 19 December 2017

List of works by Annalisa Marcuzzi

A common genetic background could explain early-onset Crohn’s disease

A comparative analysis of serologic parameters and oxidative stress in osteoarthritis and rheumatoid arthritis: reply to Mishra and colleagues.

Alendronate, a double-edged sword acting in the mevalonate pathway.

Altered germinal center reaction and abnormal B cell peripheral maturation in PI3KR1-mutated patients presenting with HIGM-like phenotype.

Autoinflammatory Diseases and Cytokine Storms—Imbalances of Innate and Adaptative Immunity

Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.

Clinical genetic testing of periodic fever syndromes

Comments on ''Geranylgeraniol--a new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw" by Ziebart T et al. (2011)

Comments to the editor concerning the paper entitled "Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways" Shiekh Tanveer Ahmad et al

Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage.

Curcumin and inflammatory bowel disease: potential and limits of innovative treatments.

Cytokine levels in the serum of healthy subjects

Cytokine profiles of women with vulvodynia: Identification of a panel of pro-inflammatory molecular targets

Database tools in genetic diseases research ⬇️

Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.

Ex vivo response to mucosal bacteria and muramyl dipeptide in inflammatory bowel disease

Family history in early-onset inflammatory bowel disease

Farnesyl and geranylgeranyl transferase inhibitors: an anti-inflammatory effect. Comment to "Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells" Haematologica. 2

Genetic and functional profiling of Crohn's disease: autophagy mechanism and susceptibility to infectious diseases

Inflammation profile of four early onset Crohn patients

Inflammatory bowel disease and patterns of volatile organic compounds in the exhaled breath of children: A case-control study using Ion Molecule Reaction-Mass Spectrometry.

Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway

Is autophagy an elective strategy to protect neurons from dysregulated cholesterol metabolism?

Letter to the Editor

Letter to the Editor: Acute Effects of Intravenous Administration of Pamidronate in Patients with Osteoporosis ⬇️

Letter: inflammatory bowel disease, complementary and alternative medicine, and genetics

Long Non-Coding RNA GAS5 and Intestinal MMP2 and MMP9 Expression: A Translational Study in Pediatric Patients with IBD

Lovastatin dose-dependently potentiates the pro-inflammatory activity of lipopolysaccharide both in vitro and in vivo

Lovastatin induces apoptosis through the mitochondrial pathway in an undifferentiated SH-SY5Y neuroblastoma cell line

Lovastatin-induced apoptosis is modulated by geranylgeraniol in a neuroblastoma cell line

Mevalonate kinase deficiency and IBD: shared genetic background.

Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis

Mevalonate kinase deficiency: disclosing the role of mevalonate pathway modulation in inflammation

Microglia activation and interaction with neuronal cells in a biochemical model of mevalonate kinase deficiency

Monocyte-predominant engraftment, cytokine levels and early transplant-related complications in pediatric hematopoietic stem cell recipients

Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients

Neuronal Dysfunction Associated with Cholesterol Deregulation.

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Presence of IL-9 in Paired Samples of Human Colostrum and Transitional Milk

Putative modifier genes in mevalonate kinase deficiency.

Serum amyloid A and cholesterol: a pivotal role on inflammation

Specific protein profile in cerebrospinal fluid from HIV-1-positive cART-treated patients affected by neurological disorders

Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study

TRAIL administration down-modulated the acute systemic inflammatory response induced in a mouse model by muramyldipeptide or lipopolysaccharide

Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.

Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study

The Complex Interplay between Lipids, Immune System and Interleukins in Cardio-Metabolic Diseases ⬇️

The effect of clodronate on a mevalonate kinase deficiency cellular model

The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.

To Extinguish the Fire from Outside the Cell or to Shutdown the Gas Valve Inside? Novel Trends in Anti-Inflammatory Therapies

Two‑gene mutation in a single patient: Biochemical and functional analysis for a correct interpretation of exome results

Type I interferon-mediated autoinflammation due to DNase II deficiency