List of works - Malika Hamdane

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

scientific article published on 2 December 2014

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.

scientific article published in October 2002

Activation of p65 NF-κB protein by p210BCR – ABL in a myeloid cell line (P210BCR – ABL activates p65 NF-κB) ⬇️

scientific article published on November 6, 1997

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

scientific article

Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology

scientific article published on 29 March 2014

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

scientific article published on 4 May 2011

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

scientific article published on April 2008

Cellular contaminants of adeno-associated virus vector stocks can enhance transduction.

scientific article published on June 1999

Chloroquine and chloroquinoline derivatives as models for the design of modulators of amyloid Peptide precursor metabolism.

scientific article

Consensus brain-derived protein, extraction protocol for the study of human and murine brain proteome using both 2D-DIGE and mini 2DE immunoblotting. ⬇️

scientific article

Determination of the human c-Abl consensus DNA binding site

scientific article published on 01 March 1998

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

scientific article published on 18 December 2012

Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

scientific article published on April 2009

Erratum: A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

article

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

scientific article published on April 2014

From tau phosphorylation to tau aggregation: what about neuronal death?

scientific article published on August 2010

Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.

scientific article

Highly successful therapeutic vaccinations combining dendritic cells and tumor cells secreting granulocyte macrophage colony-stimulating factor.

scientific article

Hippocampal BDNF expression in a tau transgenic mouse model.

scientific article published in May 2012

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

scientific article

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

scientific article

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.

scientific article published on 3 January 2007

Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?

scientific article published on September 2011

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway.

scientific article published on February 2014

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities.

scientific article published in April 2002

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.

scientific article

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

scientific article published on August 2010

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

scientific article

PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus.

scientific article

Pathological tau phenotypes. The weight of mutations, polymorphisms, and differential neuronal vulnerabilities.

scientific article published in January 2000

Pin1 allows for differential Tau dephosphorylation in neuronal cells

scientific article published on 11 May 2006

Pin1: a therapeutic target in Alzheimer neurodegeneration

scientific article published on December 2002

Progressive age-related cognitive decline in tau mice.

scientific article published in January 2013

Proteasome inhibition and Tau proteolysis: an unexpected regulation.

scientific article

Role and expression of CD40 on human retinal pigment epithelial cells

scientific article published on 01 October 2000

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

scientific article published on 14 May 2015

Stable-tau overexpression in human neuroblastoma cells: an open door for explaining neuronal death in tauopathies.

scientific article published on December 2003

Tau deletion promotes brain insulin resistance

scientific article

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

scientific article published on 25 August 2012

The DNA Binding Domain of the Human c-Abl Tyrosine Kinase Preferentially Binds to DNA Sequences Containing an AAC Motif and to Distorted DNA Structures ⬇️

scientific article published on April 28, 1998

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

scientific article

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.

scientific article published on 11 August 2016

The complex p25/Cdk5 kinase in neurofibrillary degeneration and neuronal death: the missing link to cell cycle.

scientific article published on August 2007

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

scientific journal article

Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

scientific article

Variation of endothelial nitric oxide synthase synthesis in the median eminence during the rat estrous cycle: an additional argument for the implication of vascular blood vessel in the control of GnRH release.

scientific article published in October 2001

[Molecular actors in Alzheimer's disease: which diagnostic and therapeutic consequences?].

scientific article published in September 2010

[Tau story: from frontotemporal dementia to other tauopathies]

scientific article published on 01 January 2002

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

scientific article published on March 2005

List of works by Malika Hamdane

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.

Activation of p65 NF-κB protein by p210BCR – ABL in a myeloid cell line (P210BCR – ABL activates p65 NF-κB) ⬇️

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

Cellular contaminants of adeno-associated virus vector stocks can enhance transduction.

Chloroquine and chloroquinoline derivatives as models for the design of modulators of amyloid Peptide precursor metabolism.

Consensus brain-derived protein, extraction protocol for the study of human and murine brain proteome using both 2D-DIGE and mini 2DE immunoblotting. ⬇️

Determination of the human c-Abl consensus DNA binding site

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

Erratum: A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

From tau phosphorylation to tau aggregation: what about neuronal death?

Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.

Highly successful therapeutic vaccinations combining dendritic cells and tumor cells secreting granulocyte macrophage colony-stimulating factor.

Hippocampal BDNF expression in a tau transgenic mouse model.

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.

Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway.

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities.

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus.

Pathological tau phenotypes. The weight of mutations, polymorphisms, and differential neuronal vulnerabilities.

Pin1 allows for differential Tau dephosphorylation in neuronal cells

Pin1: a therapeutic target in Alzheimer neurodegeneration

Progressive age-related cognitive decline in tau mice.

Proteasome inhibition and Tau proteolysis: an unexpected regulation.

Role and expression of CD40 on human retinal pigment epithelial cells

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

Stable-tau overexpression in human neuroblastoma cells: an open door for explaining neuronal death in tauopathies.

Tau deletion promotes brain insulin resistance

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

The DNA Binding Domain of the Human c-Abl Tyrosine Kinase Preferentially Binds to DNA Sequences Containing an AAC Motif and to Distorted DNA Structures ⬇️

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.

The complex p25/Cdk5 kinase in neurofibrillary degeneration and neuronal death: the missing link to cell cycle.

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

Variation of endothelial nitric oxide synthase synthesis in the median eminence during the rat estrous cycle: an additional argument for the implication of vascular blood vessel in the control of GnRH release.

[Molecular actors in Alzheimer's disease: which diagnostic and therapeutic consequences?].

[Tau story: from frontotemporal dementia to other tauopathies]

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.