List of works - Yohannes Tesfaigzi

A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease

scientific article published on 01 November 2018

A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease

scientific article published on 13 January 2017

A simple method for reusing western blots on PVDF membranes.

scientific article published in August 1994

A small proline-rich protein regulated by vitamin A in tracheal epithelial cells is induced in lung tumors.

scientific article

Acute and chronic nicotine exposures modulate the immune system through different pathways

scientific article published on 01 April 2000

Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells.

scientific article published on 9 August 2012

Adam8 limits the development of allergic airway inflammation in mice.

scientific article published on 13 May 2013

Adaptation of Proteasomes and Lysosomes to Cellular Environments

scientific article published on 01 October 2020

Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.

scientific article published in May 2006

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

scientific article published on 4 December 2013

An Unusual Expression of a Squamous Cell Marker, Small Proline-rich Protein Gene, in Tracheobronchial Epithelium: Differential Regulation and Gene Mapping ⬇️

scientific article published on July 1, 1992

Anti-IgE therapy results in decreased myeloid dendritic cells in asthmatic airways.

scientific article

Antioxidant Diet Protects Against Emphysema, but Increases Mortality in Cigarette Smoke-Exposed Mice ⬇️

scientific article published on August 11, 2011

Apoptosis is a pathway responsible for the resolution of endotoxin-induced alveolar type II cell hyperplasia in the rat

scientific article published on 01 October 1998

BH3-only proteins, Bmf and Bim, in autophagy

scientific article published on 8 October 2013

Bcl-2 in LPS- and allergen-induced hyperplastic mucous cells in airway epithelia of Brown Norway rats

scientific article published on 01 December 2000

Bcl-2 mediates sex-specific differences in recovery of mice from LPS-induced signs of sickness independent of IL-6

scientific article published on 01 November 2001

Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium.

scientific article published on 23 December 2004

Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria

scientific article published on 6 October 2017

Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner

scientific article published on 22 July 2017

CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model.

scientific article

Cell cycle-specific expression of G(0)SPR1 in Chinese hamster ovary cells.

scientific article published in November 1996

Chronic obstructive pulmonary disease mortality, a competing risk analysis

scientific article published on 25 October 2018

Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia.

scientific article

Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model ⬇️

scientific article published on January 11, 2011

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

scientific article published on 27 December 2016

DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS.

scientific article published on 3 October 2003

Deacetylation of p53 induces autophagy by suppressing Bmf expression

scientific journal article

Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes

scientific article published on 01 February 2020

Deletion and differential expression of p16INK4a in mouse lung tumors

scientific article published on 01 January 1997

Dietary nutrients associated with preservation of lung function in Hispanic and non-Hispanic white smokers from New Mexico.

scientific article

Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers.

scientific article published on October 2008

Differences in Health-Related Quality of Life Between New Mexican Hispanic and Non-Hispanic White Smokers.

scientific article published on 16 June 2016

Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study

scientific article published on 5 September 2017

Does the BCL-2 family member BIK control lung carcinogenesis?

scientific article published on 16 May 2018

ERS/ATS workshop report on respiratory health effects of household air pollution.

scientific article

Early Endotyping - A Chance for Intervention in COPD.

scientific article published on 9 March 2018

Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies.

scientific article published on 15 December 2009

Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in <i>Tp53</i>

scientific article published on 24 January 2022

Expanded genetic landscape of chronic obstructive pulmonary disease reveals heterogeneous cell type and phenotype associations

scholarly article published 26 June 2018

Expression of a squamous cell marker, the spr1 gene, is posttranscriptionally down-regulated by retinol in airway epithelium.

scientific article published on December 1993

Expression of the Bcl-2 protein in nasal epithelia of F344/N rats during mucous cell metaplasia and remodeling.

scientific article published in June 1998

Expression of the spr1 gene in cultured tracheal epithelial cells and its regulation by retinoids before and after confluence

scientific article published on 01 March 1996

Expression, regulation, and function of the SPR family of proteins. A review.

scientific article

Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite.

scientific article published on 16 April 2017

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

scientific article published on 25 February 2019

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

scientific article

Genotypes in matrix metalloproteinase 9 are a risk factor for COPD.

scientific article published on January 2006

Genotypes in matrix metalloproteinase 9 are risk factors for chronic obstructive pulmonary disease.

scientific article

Grading Severity of Productive Cough Based on Symptoms and Airflow Obstruction.

scientific article

Growth and differentiation of primary and passaged equine bronchial epithelial cells under conventional and air-liquid-interface culture conditions.

scientific article

Health effects of subchronic exposure to low levels of wood smoke in rats.

scientific article published in January 2002

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction

scientific article

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

scientific article published on 11 April 2009

IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.

scientific article published in May 2002

IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection.

scientific article published in September 2004

IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells.

scientific article

IL-17 Plays a Role in RSV-induced Lung Inflammation and Emphysema in Elastase and LPS-injured Mice.

scientific article published on 9 January 2018

IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway.

scientific article

Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region.

scientific article published on 14 September 2007

Induction in the expression of an unusual proline-rich protein by pig tracheal surface epithelial cells maintained in primary culture ⬇️

scientific article published on November 15, 1990

Induction of EGF receptor and erbB-2 during endotoxin-induced alveolar type II cell proliferation in the rat lung.

scientific article

Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses

scientific article published on July 2016

Inflammation, mucous cell metaplasia, and Bcl-2 expression in response to inhaled lipopolysaccharide aerosol and effect of rolipram.

scientific article

Is BMF central for anoikis and autophagy?

scientific article

Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP.

scientific article

Jumping on the Single-Cell RNA-Sequencing Bandwagon: Take Care Not to Put the Cart before the Horse

scientific article published on 01 February 2020

LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells.

scientific article published on 18 April 2003

Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia

scientific article

Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats.

scientific article published on 14 September 2005

MMP12, lung function, and COPD in high-risk populations

scientific article

Methylated Genes in Sputum Among Older Smokers With Asthma.

scientific article

New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites.

scientific article published on 8 September 2011

Normalization of FEV1/FVC Ratio to >0.7 Does Not Equal Resolution of Disease.

scientific article published on 6 November 2017

Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation.

scientific article published on 24 January 2018

Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis.

scientific article published in September 1997

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

scientific article

Ovalbumin aerosols induce airway hyperreactivity in naïve DO11.10 T cell receptor transgenic mice without pulmonary eosinophilia or OVA-specific antibody.

scientific article

Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease

scientific article published on 07 December 2020

Persistent mucus accumulation: a consequence of delayed bronchial mucous cell apoptosis in RAO-affected horses?

scientific article published on 24 February 2006

Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness.

scientific article

Processes involved in the repair of injured airway epithelia.

scientific article published on January 2003

Proportion of phage-insensitive and phage-sensitive cells within pure strains of lactic streptococci, and the influence of calcium

scientific article published on 01 February 1989

Regulation of mucous cell metaplasia in bronchial asthma.

scientific article published on August 2008

Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness.

scientific article published in June 2001

Response of rats to low levels of sarin.

scientific article published in October 2002

Role of hypothalamic interleukin-1beta in fever induced by cecal ligation and puncture in rats.

scientific article published in September 1998

SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.

scientific article

STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma.

scientific article published in June 2007

Simultaneous preparation of RNA and nuclei for northern blot and flow cytometric analysis

scientific article published on 01 November 1996

Softwares and methods for estimating genetic ancestry in human populations ⬇️

scientific article published on January 5, 2013

Spirometric variability in smokers: transitions in COPD diagnosis in a five-year longitudinal study.

scientific article

T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways.

scientific article published on 20 October 2016

The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death.

scientific article published on November 2008

The Course of Lung Function in Middle-aged Heavy Smokers: Incidence and Time to Early Onset of Chronic Obstructive Pulmonary Disease

scientific article published on 01 December 2018

Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces

scientific article published on 24 April 2019

Two nuclear proteins in tracheal epithelial cells are recognized by antibodies specific to a squamous differentiation marker, sprl ⬇️

scientific article published on September 1, 1995

Wildfire smoke exposure and human health: Significant gaps in research for a growing public health issue.

scientific article

Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers.

scientific article

List of works by Yohannes Tesfaigzi

A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease

A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease

A simple method for reusing western blots on PVDF membranes.

A small proline-rich protein regulated by vitamin A in tracheal epithelial cells is induced in lung tumors.

Acute and chronic nicotine exposures modulate the immune system through different pathways

Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells.

Adam8 limits the development of allergic airway inflammation in mice.

Adaptation of Proteasomes and Lysosomes to Cellular Environments

Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

An Unusual Expression of a Squamous Cell Marker, Small Proline-rich Protein Gene, in Tracheobronchial Epithelium: Differential Regulation and Gene Mapping ⬇️

Anti-IgE therapy results in decreased myeloid dendritic cells in asthmatic airways.

Antioxidant Diet Protects Against Emphysema, but Increases Mortality in Cigarette Smoke-Exposed Mice ⬇️

Apoptosis is a pathway responsible for the resolution of endotoxin-induced alveolar type II cell hyperplasia in the rat

BH3-only proteins, Bmf and Bim, in autophagy

Bcl-2 in LPS- and allergen-induced hyperplastic mucous cells in airway epithelia of Brown Norway rats

Bcl-2 mediates sex-specific differences in recovery of mice from LPS-induced signs of sickness independent of IL-6

Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium.

Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria

Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner

CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model.

Cell cycle-specific expression of G(0)SPR1 in Chinese hamster ovary cells.

Chronic obstructive pulmonary disease mortality, a competing risk analysis

Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia.

Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model ⬇️

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS.

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes

Deletion and differential expression of p16INK4a in mouse lung tumors

Dietary nutrients associated with preservation of lung function in Hispanic and non-Hispanic white smokers from New Mexico.

Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers.

Differences in Health-Related Quality of Life Between New Mexican Hispanic and Non-Hispanic White Smokers.

Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study

Does the BCL-2 family member BIK control lung carcinogenesis?

ERS/ATS workshop report on respiratory health effects of household air pollution.

Early Endotyping - A Chance for Intervention in COPD.

Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies.

Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in <i>Tp53</i>

Expanded genetic landscape of chronic obstructive pulmonary disease reveals heterogeneous cell type and phenotype associations

Expression of a squamous cell marker, the spr1 gene, is posttranscriptionally down-regulated by retinol in airway epithelium.

Expression of the Bcl-2 protein in nasal epithelia of F344/N rats during mucous cell metaplasia and remodeling.

Expression of the spr1 gene in cultured tracheal epithelial cells and its regulation by retinoids before and after confluence

Expression, regulation, and function of the SPR family of proteins. A review.

Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite.

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Genotypes in matrix metalloproteinase 9 are a risk factor for COPD.

Genotypes in matrix metalloproteinase 9 are risk factors for chronic obstructive pulmonary disease.

Grading Severity of Productive Cough Based on Symptoms and Airflow Obstruction.

Growth and differentiation of primary and passaged equine bronchial epithelial cells under conventional and air-liquid-interface culture conditions.

Health effects of subchronic exposure to low levels of wood smoke in rats.

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.

IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection.

IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells.

IL-17 Plays a Role in RSV-induced Lung Inflammation and Emphysema in Elastase and LPS-injured Mice.

IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway.

Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region.

Induction in the expression of an unusual proline-rich protein by pig tracheal surface epithelial cells maintained in primary culture ⬇️

Induction of EGF receptor and erbB-2 during endotoxin-induced alveolar type II cell proliferation in the rat lung.

Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses

Inflammation, mucous cell metaplasia, and Bcl-2 expression in response to inhaled lipopolysaccharide aerosol and effect of rolipram.

Is BMF central for anoikis and autophagy?

Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP.

Jumping on the Single-Cell RNA-Sequencing Bandwagon: Take Care Not to Put the Cart before the Horse

LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells.

Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia

Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats.

MMP12, lung function, and COPD in high-risk populations

Methylated Genes in Sputum Among Older Smokers With Asthma.

New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites.

Normalization of FEV1/FVC Ratio to >0.7 Does Not Equal Resolution of Disease.

Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation.

Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis.

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

Ovalbumin aerosols induce airway hyperreactivity in naïve DO11.10 T cell receptor transgenic mice without pulmonary eosinophilia or OVA-specific antibody.

Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease