Search filters

List of works by Pui Lai Rachel Ee

A role for Ubc9 in tumorigenesis

scientific article published on 01 April 2005

Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20.

scientific article published on July 2004

Anti-mycobacterial activities of synthetic cationic α-helical peptides and their synergism with rifampicin.

scientific article published on 4 December 2013

Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.

scientific article

Biodegradable functional polycarbonate micelles for controlled release of amphotericin B.

scientific article

Biodegradable poly(ethylene glycol)-peptide hydrogels with well-defined structure and properties for cell delivery.

scientific article

Biomimetic hydrogels for chondrogenic differentiation of human mesenchymal stem cells to neocartilage.

scientific article published on October 2010

Broad-spectrum antimicrobial and biofilm-disrupting hydrogels: stereocomplex-driven supramolecular assemblies

scientific article published on 19 November 2012

Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes.

scientific article published on 11 March 2017

Clinical Efficacy of Polymyxin Monotherapy versus Nonvalidated Polymyxin Combination Therapy versus Validated Polymyxin Combination Therapy in Extensively Drug-Resistant Gram-Negative Bacillus Infections.

scientific article published on 18 April 2016

Curcumin Analogues with Potent and Selective Anti‐proliferative Activity on Acute Promyelocytic Leukemia: Involvement of Accumulated Misfolded Nuclear Receptor Co‐repressor (N‐CoR) Protein as a Basis for Selective Activity ⬇️

scientific article published on August 6, 2012

Designing α-helical peptides with enhanced synergism and selectivity against Mycobacterium smegmatis: Discerning the role of hydrophobicity and helicity

scientific article published on 14 September 2015

Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).

scientific article published on 3 August 2008

Disruption of drug-resistant biofilms using de novo designed short α-helical antimicrobial peptides with idealized facial amphiphilicity

scientific article published on 27 April 2017

Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: downregulating mRNA expression level and sensitizing cancer cells to anticancer drug

scientific article

Facile and efficient encapsulation of antimicrobial peptides via crosslinked DNA nanostructures and their application in wound therapy

scientific article published on 16 October 2019

Functionalized curcumin analogs as potent modulators of the Wnt/β-catenin signaling pathway.

scientific article published on 7 November 2013

Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells

scientific article published on 11 May 2011

Injectable Biodegradable Poly(ethylene glycol)/RGD Peptide Hybrid Hydrogels for in vitro Chondrogenesis of Human Mesenchymal Stem Cells.

scientific article published on 25 May 2010

Macromolecular Conjugate and Biological Carrier Approaches for the Targeted Delivery of Antibiotics.

scientific article published on 4 July 2017

Metabotyping of docosahexaenoic acid - treated Alzheimer's disease cell model

scientific article

Mixed micelles self-assembled from block copolymers for drug delivery

Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues.

scientific article

Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference.

scientific article published in December 2004

Nanostructured PEG-based hydrogels with tunable physical properties for gene delivery to human mesenchymal stem cells ⬇️

scientific article published on June 15, 2012

Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells

scientific article

Novel biodegradable block copolymers of poly(ethylene glycol) (PEG) and cationic polycarbonate: effects of peg configuration on gene delivery

scientific article

Nucleic acid peptide nanogels for the treatment of bacterial keratitis

scientific article published on 14 August 2020

Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs.

scientific article published on April 2004

Polymer- and lipid-based nanoparticle therapeutics for the treatment of liver diseases

article published in 2010

Rational design of biodegradable cationic polycarbonates for gene delivery

article

St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

scientific article published on 21 July 2006

Stability and efficacy of synthetic cationic antimicrobial peptides nebulized using high frequency acoustic waves.

scientific article

Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity.

scientific article published on 8 January 2014

The effects of polymeric nanostructure shape on drug delivery

scientific article published on 06 July 2011

The role of PEG architecture and molecular weight in the gene transfection performance of PEGylated poly(dimethylaminoethyl methacrylate) based cationic polymers

scientific article published on 24 December 2010

The role of modulation of antioxidant enzyme systems in the treatment of neurodegenerative diseases

scientific article

Ultra-Short Antimicrobial Peptoids Show Propensity for Membrane Activity Against Multi-Drug Resistant Mycobacterium tuberculosis

scientific article published on 17 March 2020

Understanding the cholesterol metabolism-perturbing effects of docosahexaenoic acid by gas chromatography-mass spectrometry targeted metabonomic profiling

scientific article published on October 2015

Unnatural amino acid analogues of membrane-active helical peptides with anti-mycobacterial activity and improved stability

scientific article

Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells

scientific article published on 7 May 2015

Paulina is supported by:

About Paulina

Help