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List of works by Cecile Janssens

'It might happen or it might not': how patients with multiple sclerosis explain their perception of prognostic risk

scientific article

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

scientific article

A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health

article

A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions

scientific article published on March 2008

A critical evaluation of the algorithm behind the Relative Citation Ratio (RCR).

scientific article published on 2 October 2017

A genome-wide linkage study of individuals with high scores on NEO personality traits

scientific article published on 09 August 2011

A genome-wide screen for depression in two independent Dutch populations

scientific article published on 8 May 2010

A methodological perspective on genetic risk prediction studies in type 2 diabetes: recommendations for future research

scientific article published on December 2011

A new logistic regression approach for the evaluation of diagnostic test results

scientific article

A study of the SORL1 gene in Alzheimer's disease and cognitive function

scientific article published in January 2009

A systematic review and critical assessment of 11 discordant meta-analyses on reduced-function CYP2C19 genotype and risk of adverse clinical outcomes in clopidogrel users

scientific article published on 19 June 2014

A tiered-layered-staged model for informed consent in personal genome testing ⬇️

scientific article published on November 21, 2012

Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives

scientific article published in September 2011

Adaptation is favorable for most patients with multiple sclerosis

scientific article published in November 2004

An Electrocardiogram-Based Risk Equation for Incident Cardiovascular Disease From the National Health and Nutrition Examination Survey

scientific article published on 3 August 2016

An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses

scientific article published in March 2009

Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results

scientific article published on 30 May 2012

Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study

scientific article published in August 2008

Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up.

scientific article

Anxiety and depression influence the relation between disability status and quality of life in multiple sclerosis

scientific article published in August 2003

Apolipoprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study

scientific article

Assessing predictive performance beyond the Framingham risk score.

scientific article published in April 2010

Assessment of Improved Prediction Beyond Traditional Risk Factors

scientific article published on 01 February 2010

Assessment of pharmacogenetic tests: presenting measures of clinical validity and potential population impact in association studies

scientific article

B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies

scientific article published on 18 July 2014

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

CHOLESTERYL ESTER TRANSFER PROTEIN GENE AND CORONARY HEART DISEASE MORTALITY: THE ROTTERDAM STUDY

article

CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease.

scientific article

Callosal lesion predicts future attacks after clinically isolated syndrome.

scientific article published on December 2009

Carriage of reduced-function CYP2C19 allele among patients treated with clopidogrel

scientific article published in February 2011

Clinical Implications of Old and New Genes for Open-Angle Glaucoma

article

Comparison of participant information and informed consent forms of five European studies in genetic isolated populations

scientific article (publication date: March 2010)

Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk

scientific article

Correction: A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health

article

Cost Effectiveness of Age-specific Screening Intervals for People With Family Histories of Colorectal Cancer

scientific article published on 27 September 2017

Cost-Effectiveness of Risk-Stratified Colorectal Cancer Screening Based on Polygenic Risk: Current Status and Future Potential

scientific article published on 14 October 2019

Cox proportional hazards models have more statistical power than logistic regression models in cross-sectional genetic association studies

article

Defining Evidence for Precision Medicine: A Patient Is More Than a Set of Covariates

scientific article published on 01 May 2019

Designing babies through gene editing: science or science fiction?

scientific article published on 7 April 2016

Discriminative accuracy of genomic profiling comparing multiplicative and additive risk models

scientific article

Divorce and unemployment in multiple sclerosis: recalculation of the data of Morales-Gonzáles J M, Benito-Leon J, Rivera-Navarro J and Mitchell A J.

scientific article published in December 2004

Does genetic testing really improve the prediction of future type 2 diabetes?

scientific article

Early Age at Menopause is Associated with Increased risk of Dementia and Mortality in Women with Down Syndrome

scientific article published on 01 January 2010

Erratum

scholarly article published in Medical Decision Making

Erratum to: Novel citation-based search method for scientific literature: application to meta-analyses

scientific article published on 10 November 2015

Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

scientific article

Ethnic differences and parental beliefs are important for overweight prevention and management in children: a cross-sectional study in the Netherlands

scientific article

Ethnicity, educational level and attitudes contribute to parental intentions about genetic testing for child obesity

scientific article published on 7 February 2013

Evaluation of polygenic risk models using multiple performance measures: a critical assessment of discordant results.

scientific article published on 12 June 2018

Evaluation of risk prediction updates from commercial genome-wide scans

article by Raluca Mihaescu et al published 25 July 2009 in Genetics in Medicine

Expectations of wheelchair-dependency in recently diagnosed patients with multiple sclerosis and their partners

scientific article published in May 2003

External validation is only needed when prediction models are worth it (Letter commenting on: J Clin Epidemiol. 2015;68:25-34).

scientific article published on 3 February 2015

Eye color and the prediction of complex phenotypes from genotypes.

scientific article

Family history and the natural history of colorectal cancer: systematic review

scientific article published on 15 January 2015

Fatigue: an important feature of late-onset Pompe disease

scientific article published on 02 March 2007

Finding Wealth in Waste: Irreplicability Re-Examined

Five genetic variants associated with prostate cancer

scientific article published on 01 June 2008

Genetic architecture of circulating lipid levels

scientific article

Genetic architecture of open angle glaucoma and related determinants

scientific article published on 7 November 2010

Genetic factors influence the clustering of depression among individuals with lower socioeconomic status

scientific article

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

scientific article

Genetic scoring analysis: a way forward in genome wide association studies?

scientific article published on January 2009

Genome-based prediction of breast cancer risk in the general population: a modeling study based on meta-analyses of genetic associations

scientific article published on January 2011

Genome-based prediction of common diseases: advances and prospects

scientific article

Genome-wide analysis of genetic loci associated with Alzheimer disease

scientific article

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

scientific article

Genome-wide association scan for five major dimensions of personality

scientific article

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

scientific article

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide profiling of blood pressure in adults and children

scientific article published on 27 December 2011

HFE gene mutations increase the risk of coronary heart disease in women.

scientific article

Health-related quality of life in patients with musculoskeletal complaints in a general acupuncture practice: an observational study

scientific article published on 19 July 2010

Heritability of dietary food intake patterns

scientific article published on 15 March 2012

How Attitudes Research Contributes to Overoptimistic Expectations of Personal Genome Testing

journal article; published in The American Journal of Bioethics in 2009

How can polygenic inheritance be used in population screening for common diseases?

scientific article

IGF-1 CA repeat variant and breast cancer risk in postmenopausal women

scientific article published on 11 June 2007

Impact of communicating familial risk of diabetes on illness perceptions and self-reported behavioral outcomes: a randomized controlled trial

scientific article published on 08 January 2009

Impact of presymptomatic genetic testing for hereditary ataxia and neuromuscular disorders: where is the evidence?

scientific article published in January 2005

Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners ⬇️

scientific article published on December 1, 2003

Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve

article by Raluca Mihaescu et al published 18 June 2010 in American Journal of Epidemiology

Incremental value of rare genetic variants for the prediction of multifactorial diseases

scientific article published on 20 August 2013

Informed Consent in Direct‐to‐Consumer Personal Genome Testing: The Outline of A Model between Specific and Generic Consent ⬇️

scientific article published on November 8, 2012

Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study

scientific article

Interpreting Incremental Value of Markers Added to Risk Prediction Models ⬇️

scientific article published on August 8, 2012

Is the time right for translation research in genomics?

scientific article published on 01 January 2008

It is time to get real when trying to predict educational performance

scientific article published on 13 March 2020

Longevity candidate genes and their association with personality traits in the elderly

scientific article

Lowering the P Value Threshold

Menopause impacts the relation of plasma adiponectin levels with the metabolic syndrome

scientific article published on 26 August 2009

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

scientific article

Meta-analysis of genome-wide association studies for personality.

scientific article published on 21 December 2010

Migraine is not associated with enhanced atherosclerosis

scientific article published on 12 November 2012

Most published research findings are false-but a little replication goes a long way

scientific article

Naming and framing in genomic testing

scholarly article by Eline M. Bunnik published in February 2014

No association between the angiotensin-converting enzyme gene and major depression: a case???control study and meta-analysis

article

Novel citation-based search method for scientific literature: a validation study

scientific article published on 07 February 2020

Novel citation-based search method for scientific literature: application to meta-analyses

scientific article published on 13 October 2015

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Patients with Barrett's esophagus perceive their risk of developing esophageal adenocarcinoma as low

scientific article published on 01 January 2007

Patients with multiple sclerosis prefer early diagnosis

scientific article published on 01 May 2004

Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution".

scientific article

Perception of prognostic risk in patients with multiple sclerosis: the relationship with anxiety, depression, and disease-related distress

scientific article published in February 2004

Personal genome testing: test characteristics to clarify the discourse on ethical, legal and societal issues

scientific article

Personal utility in genomic testing: is there such a thing?

scientific article published on 28 May 2014

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History

scientific article published on 27 August 2020

Perspectives on the use of multiple sclerosis risk genes for prediction

scientific article

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome

scientific article published on 29 September 2011

PredictABEL: an R package for the assessment of risk prediction models ⬇️

scientific article published on March 24, 2011

Predicting Polygenic Obesity Using Genetic Information

scientific article

Predicting human height by Victorian and genomic methods

scientific article

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

scientific article published on 11 August 2008

Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models

scientific article

Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors

scientific article

Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium

scientific article published on 10 October 2013

Prediction of anxiety and distress following diagnosis of multiple sclerosis: a two-year longitudinal study

scientific article published in December 2006

Predictive Value of Multiple Genetic Testing for Age-Related Macular Degeneration

scientific article published on 01 September 2007

Predictive ability of direct-to-consumer pharmacogenetic testing: when is lack of evidence really lack of evidence?

scientific article published in March 2013

Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability

scientific article published on 28 July 2011

Predictive genetic testing for type 2 diabetes

scientific article published in September 2006

Predictive or not predictive: understanding the mixed messages from the patient's DNA sequence

scientific article

Predictive testing for complex diseases using multiple genes: fact or fiction?

scientific article published on July 2006

Pregnancy in multiple sclerosis: clinical and self-report scales

scientific article published on 3 August 2011

Prenatal exposure to the 1944-45 Dutch 'hunger winter' and addiction later in life

scientific article published on 8 January 2008

Proprietary Algorithms for Polygenic Risk: Protecting Scientific Innovation or Hiding the Lack of It?

scientific article published on 13 June 2019

Quality criteria for health checks: development of a European consensus agreement

scientific article published on 10 August 2014

ROC curves for clinical prediction models Part 4: Selection of the risk threshold: once chosen, always the same?

scientific article published on 17 June 2020

Racial/Ethnic Variation in the Association of Lipid-Related Genetic Variants With Blood Lipids in the US Adult Population

Raw data: access to inaccuracy

scientific article published in February 2014

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

scientific article published on 05 December 2012

Reflection on modern methods: Revisiting the area under the ROC Curve

scientific article published on 22 January 2020

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis

scientific article

Reply to Stephan et al.

scientific article published on 3 July 2008

Reply to “Disease risks derived from genetic variants need clinical context”

Research Conducted Using Data Obtained through Online Communities: Ethical Implications of Methodological Limitations

scientific article (publication date: 2012)

Response to letter Dr Gail

scientific article published on 01 May 2017

Returning pharmacogenetic secondary findings from genome sequencing: let's not put the cart before the horse.

scientific article published on 7 May 2015

Revisiting the clinical validity of multiplex genetic testing in complex diseases

scientific article published on March 2004

Risk Analysis of Prostate Cancer in PRACTICAL Consortium-Letter

scientific article published on 01 January 2016

Risk prediction models: a framework for assessment

scientific article published on 14 December 2011

Role of shared genetic and environmental factors in symptoms of depression and body composition

article

Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement

scientific article published on 08 January 2014

Self reported stressful life events and exacerbations in multiple sclerosis: prospective study ⬇️

scientific article published on September 20, 2003

Shared genetic factors in migraine and depression: evidence from a genetic isolate

scientific article

Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors

scientific article

Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium

scientific article published on 18 March 2013

Small improvement in the area under the receiver operating characteristic curve indicated small changes in predicted risks

scientific article published on 15 July 2016

Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement

scientific article published on 15 March 2011

Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration

scientific article published on 16 March 2011

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

scientific article

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

scientific article published on 16 March 2011

Strengthening the reporting of Genetic Risk Prediction Studies: The GRIPS statement

scientific article published on 01 May 2011

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

scientific article

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

scientific article (publication date: April 2011)

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement

scientific article published in March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

scientific article published on 16 March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

scientific article published on 15 March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.

scientific article

Survival in elderly persons with Down syndrome

scientific article published in December 2008

The ROC plot: the picture that could be worth a 1000 words

scientific article published on 17 June 2020

The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop

scientific article

The apolipoprotein E gene and its age-specific effects on cognitive function

scientific article

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

scientific article

The hidden harm behind the return of results from personal genome services: a need for rigorous and responsible evaluation

scientific article published on 20 November 2014

The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases

scientific article published on August 2007

The role of disability and depression in cognitive functioning within 2 years after multiple sclerosis diagnosis

scientific article published on 20 May 2008

The role of disease characteristics in the ethical debate on personal genome testing

scientific article

The sense and nonsense of direct-to-consumer genetic testing for cardiovascular disease

scientific article

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

scientific article

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

scientific article

Towards predictive genetic testing of complex diseases

scientific article published on 08 December 2006

Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives

scientific article published on January 2010

Two Authors Reply

Use of genomic profiling to assess risk for cardiovascular disease and identify individualized prevention strategies--a targeted evidence-based review

scientific article published on December 2010

Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia

scientific article

Useless until proven effective: the clinical utility of preemptive pharmacogenetic testing

scientific article published in December 2014

Using family history information to promote healthy lifestyles and prevent diseases; a discussion of the evidence

scientific article

Validity of polygenic risk scores: are we measuring what we think we are?

scientific article published on 01 November 2019

Value of EUS in Determining Curative Resectability in Reference to CT and FDG-PET: The Optimal Sequence in Preoperative Staging of Esophageal Cancer?

scientific article published on 06 May 2011

Value of genetic profiling for the prediction of coronary heart disease

scientific article

Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile

scientific article published on September 2006

Variations in predicted risks in personal genome testing for common complex diseases

scientific article

Whole genome sequencing--new opportunities for health care practice?

scientific article published on 01 January 2010

Why Realistic Test Scenarios in Translational Genomics Research Remain Hypothetical

scientific article published on 03 September 2009

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