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List of works by Matthew P McCormack

A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

scientific article

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis.

scientific article

A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics

scientific article published on 19 October 2020

Analysis of Histone Modifications in Acute Myeloid Leukaemia Using Chromatin Immunoprecipitation.

scientific article published in January 2018

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

scientific article published on 01 May 2003

Expression of activated mutants of the human interleukin-3/interleukin-5/granulocyte-macrophage colony-stimulating factor receptor common beta subunit in primary hematopoietic cells induces factor-independent proliferation and differentiation

scientific article published on 01 August 1997

Hhex induces promyelocyte self-renewal and cooperates with growth factor independence to cause myeloid leukemia in mice

scientific article published on 01 February 2018

Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.

scientific article published on 6 October 2014

Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency

scientific article published on 10 December 2016

Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.

scientific article published on 27 April 2016

Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor beta subunit.

scientific article

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

scientific article published on 28 January 2009

Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.

scientific article published on 7 August 2013

The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development

scientific article published on December 2003

The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1

scientific article published on 30 January 2019

The molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia.

scientific article published on 22 September 2010

The thymus under siege: Lmo2 induces precancerous stem cells in a mouse model of T-ALL.

scientific article published on 15 June 2010

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

scientific article