List of works - L. David Finger

Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways

scientific article

Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction.

scientific article published in June 2004

DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction.

scientific article

Flap Endonuclease 1 Mutations A159V and E160D Cause Genomic Instability by Slowing Reaction on Double-Flap Substrates

scientific article published on 05 December 2018

Functional regulation of FEN1 nuclease and its link to cancer ⬇️

scientific article published on October 6, 2010

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

scientific article

Interstrand disulfide crosslinking of DNA bases supports a double nucleotide unpairing mechanism for flap endonucleases

article

Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases.

scientific article

Observation of unpaired substrate DNA in the flap endonuclease-1 active site.

scientific article published on 23 August 2013

Proline scanning mutagenesis reveals a role for the flap endonuclease-1 helical cap in substrate unpairing

scientific article published on 14 October 2013

Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids.

scientific article

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

scientific article

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin

scientific article

The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis

scientific article

The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

scientific article

The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.

scientific article

The wonders of flap endonucleases: structure, function, mechanism and regulation.

scientific article published on January 2012

Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases

scientific article

List of works by L. David Finger

Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways

Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction.

DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction.

Flap Endonuclease 1 Mutations A159V and E160D Cause Genomic Instability by Slowing Reaction on Double-Flap Substrates

Functional regulation of FEN1 nuclease and its link to cancer ⬇️

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

Interstrand disulfide crosslinking of DNA bases supports a double nucleotide unpairing mechanism for flap endonucleases

Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases.

Observation of unpaired substrate DNA in the flap endonuclease-1 active site.

Proline scanning mutagenesis reveals a role for the flap endonuclease-1 helical cap in substrate unpairing

Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids.

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin

The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis

The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.

The wonders of flap endonucleases: structure, function, mechanism and regulation.

Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases