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List of works by Hermelijn H Smits

A limited role for regulatory T cells in post-ischemic neovascularization

scientific article

Akkermansia muciniphila Exerts Lipid-Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3-Leiden.CETP Mice

scientific article published on 06 August 2019

Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis

scientific article

Asymptomatic plasmodial infection is associated with increased tumor necrosis factor receptor II-expressing regulatory T cells and suppressed type 2 immune responses

scientific article

B cells in allergic diseases: Bad or Better? ⬇️

scientific article published on August 1, 2012

CD11b and L‐selectin expression on eosinophils and neutrophils in blood and induced sputum of patients with asthma compared with normal subjects ⬇️

scientific article published on May 1, 1998

CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide

scientific article published in April 2014

CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry

scientific article published on September 2002

CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel

scientific article published on 20 August 2015

Childhood allergies and asthma: New insights on environmental exposures and local immunity at the lung barrier

scientific article

Cholera toxin B suppresses allergic inflammation through induction of secretory IgA.

scientific article published on 29 April 2009

Chronic helminth infections modulate allergen-specific immune responses: Protection against development of allergic disorders?

scientific article published on 13 June 2007

Chronic helminth infections protect against allergic diseases by active regulatory processes

scientific article

Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development

scientific article

Correspondence to "Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments"

scientific article published on 01 June 2020

Corrigendum: Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses

article

Cytokine and chemokine profile of the innate and adaptive immune response of Schistosoma haematobium and Plasmodium falciparum single and co-infected school-aged children from an endemic area of Lambaréné, Gabon

scientific article

Cytokine release and its modulation by dexamethasone in whole blood following exercise ⬇️

scientific article published on 01 February 1998

DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

scientific article published on 30 April 2020

Dendritic cell-mediated T cell polarization

scientific article

Different faces of regulatory DCs in homeostasis and immunity

scientific article

E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

scientific article published on 31 July 2015

Early Induction of Human Regulatory Dermal Antigen Presenting Cells by Skin-Penetrating Cercariae

scientific article published on 31 October 2018

Early origins of lung disease: towards an interdisciplinary approach

scientific article published on 01 September 2020

Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo

scientific article published on 01 January 1997

Environmental 24-hr Cycles Are Essential for Health

scientific article published on 13 July 2016

Establishing the Production of Male Schistosoma mansoni Cercariae for a Controlled Human Infection Model

scientific article published on 01 August 2018

Extract of Helicobacter pylori Ameliorates Parameters of Airway Inflammation and Goblet Cell Hyperplasia following Repeated Allergen Exposure

scientific article published on 26 June 2019

Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.

scientific article published on 6 February 2018

Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection

scientific article

Genomic organization of the human interleukin-12 receptor beta2-chain gene

scientific article (publication date: 2000)

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

scientific article published on October 2004

Helminth infections: protection from atopic disorders

scientific article

Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses

scientific article published on June 2010

Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease

scientific article published on 19 May 2020

How to Deal with Polarized Th2 Cells: Exploring the Achilles’ Heel ⬇️

scientific article published on October 1, 2001

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells

scientific article

IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut.

scientific article

IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.

scientific article

IL-4 Is a Mediator of IL-12p70 Induction by Human Th2 Cells: Reversal of Polarized Th2 Phenotype by Dendritic Cells

scientific article published on 01 August 2000

Impaired Perception of Dyspnea in Patients with Severe Asthma

scientific article published on 01 October 1998

In utero priming by worms protects against respiratory allergies

scientific article published on 28 October 2014

Inflammatory and tolerogenic myeloid cells determine outcome following human allergen challenge

scientific article published in 2023

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

scientific article published on 30 July 2019

Innate, adaptive and regulatory responses in schistosomiasis: relationship to allergy

scientific article

Intercellular Adhesion Molecule-1/LFA-1 Ligation Favors Human Th1 Development

article

Interleukin 10 (IL-10)–Producing CD1dhi Regulatory B Cells From Schistosoma Haematobium–Infected Individuals Induce IL-10–Positive T Cells and Suppress Effector T-Cell Cytokines

scientific article published on 01 May 2014

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation

scientific article published on 16 September 2018

LIM-only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation

scientific article published on 24 August 2015

Longitudinal study of changes in γδ T cells and CD4+ T cells upon asymptomatic malaria infection in Indonesian children

scientific article published on 18 August 2017

Microbes and asthma: Opportunities for intervention

scientific article

Microorganism-induced suppression of allergic airway disease: novel therapies on the horizon?

scientific article

Modulating local airway immune responses to treat allergic asthma: lessons from experimental models and human studies

scientific article published on 04 February 2020

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

scientific article published on 01 November 2018

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

scientific article published on 27 July 2009

Pathogen-Derived Extracellular Vesicle-Associated Molecules That Affect the Host Immune System: An Overview

scientific article published in 2018

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

scientific article

Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout <i>Schistosoma mansoni</i> Infection

scientific article published on 30 August 2021

Potential of immunoglobulin A to prevent allergic asthma

scientific article published on 11 April 2013

Preschool wheezing diagnosis and management-Survey of physicians' and caregivers' perspective

scientific article published on 18 November 2019

Production and glyco-engineering of immunomodulatory helminth glycoproteins in plants

scientific article published on 10 April 2017

Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection

scientific article published on 8 August 2007

Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load.

scientific article

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells

scientific article published on 9 July 2013

Regulatory B-cell induction by helminths: implications for allergic disease

scientific article published on October 2011

Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum

scientific article

Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics

scientific article

Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma

scientific article published on 01 December 1996

Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4+ T-lymphocyte responses and HIV-1 infection in vitro

scientific article published on 05 September 2019

Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses

article

Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells.

scientific article

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

scientific article

Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function.

scientific article published on 3 April 2017

Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells

scientific article (publication date: 2012)

Selection of probiotic bacteria for prevention of allergic diseases: immunomodulation of neonatal dendritic cells.

scientific article published on 22 May 2007

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin

scientific article

Specific glycan elements determine differential binding of individual egg glycoproteins of the human parasite Schistosoma mansoni by host C-type lectin receptors

scientific article published on January 2012

Sustained IL-12 signaling is required for Th1 development

scientific article published in January 2004

T-helper 17 cells are associated with pathology in human schistosomiasis

scientific article published on 19 October 2012

The effect of tiotropium in combination with olodaterol on house dust mite-induced allergic airway disease

scientific article

The evolutionary role of the IL-33/ST2 system in host immune defence

scientific article published on 03 January 2013

The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β.

scientific article

Therapeutic Application of an Extract of Helicobacter pylori Ameliorates the Development of Allergic Airway Disease

scientific article published on 19 January 2018

Toll-like receptor ligation for the induction of regulatory B cells

scientific article published on January 2014

Type I interferons provide additive signals for murine regulatory B cell induction by Schistosoma mansoni eggs

scientific article published on 29 May 2019

Worms: Pernicious parasites or allies against allergies?

scientific article published on 29 August 2018

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