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List of works by Edward Frank Knol

2S protein Ara h 7.0201 has unique epitopes compared to other Ara h 7 isoforms and is comparable to 2S proteins Ara h 2 and 6 in basophil degranulation capacity.

scientific article published on 14 March 2018

<scp>EAACI</scp> guidelines on the diagnosis of <scp>IgE</scp>‐mediated food allergy

scientific article published in 2023

A field-applicable method for flow cytometric analysis of granulocyte activation: Cryopreservation of fixed granulocytes

scientific article published on 13 March 2018

A new framework for the interpretation of IgE sensitization tests

scientific article

A panel of biomarkers for disease severity in atopic dermatitis

scientific article published on 01 March 2015

A search for biomarkers as diagnostic tools for food allergy: a pilot study in peanut-allergic patients.

scientific article

A specific mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy

scientific article published on 27 May 2008

ARIA-EAACI statement on Asthma and COVID-19 (June 2, 2020)

scientific article published on 26 June 2020

Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients

scientific article published on 09 October 2008

Absence of T-regulatory cell expression and function in atopic dermatitis skin

scientific article published on 01 January 2006

Accessory cells with a morphology and marker pattern of dendritic cells can be obtained from elutriator-purified blood monocyte fractions. An enhancing effect of metrizamide in this differentiation

scientific article published on 01 October 1989

Adhesion molecule expression on skin endothelia in atopic dermatitis: effects of TNF-alpha and IL-4

scientific article published on 01 September 1998

Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis

scientific article published on 6 January 2017

Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review

scientific article published on 05 July 2016

Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis

scientific article published on 11 May 2017

Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews.

scientific article published on 08 August 2017

Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systematic review.

scientific article published on 22 March 2016

Allergen-specific Th2 responses in young children precede sensitization later in life

scientific article published on 28 January 2014

Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy [...]

scientific article

Altered expression of fatty acid desaturases in the skin of dogs with atopic dermatitis

scientific article published on 21 January 2009

An improved method for the purification of basophilic granulocytes from human blood

scientific article published on 01 May 1992

Anaphylaxis to cow's milk formula containing short-chain galacto-oligosaccharide

article

Anti-IL-5 recombinant humanized monoclonal antibody (mepolizumab) for the treatment of atopic dermatitis.

scientific article published in May 2005

Application of multiplexed immunoglobulin E determination on a chip in component-resolved diagnostics in allergy.

scientific article published on 11 November 2009

Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

scientific article (publication date: 2017)

Ara h 2 is the best predictor for peanut allergy in adults.

scientific article

Assessment of cyclobutane pyrimidine dimers by digital photography in human skin.

scientific article

Atopic dermatitis: A tale of two distinct pathomechanisms that make you itch.

scientific article published in November 2016

Atopy patch test in patients with atopic eczema/dermatitis syndrome: comparison of petrolatum and aqueous solution as a vehicle

scientific article published on 01 April 2004

Basophil stimulation and signaling pathways

scientific article published on 01 January 2014

Basophils and antigen presentation: of mice and not men?

scientific article published on 01 May 2012

Basophils and mast cells: Underdog in immune regulation? ⬇️

scientific article published on February 17, 2011

Basophils from patients with allergic asthma show a primed phenotype☆☆☆★

scientific article published on 01 November 1999

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper.

scientific article published on 2 February 2017

CD11b+ cells and ultraviolet-B-resistant CD1a+ cells in skin of patients with polymorphous light eruption

scientific article published on 01 July 1999

CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17, and IL-22.

scientific article published on 6 December 2012

Cell-surface expression of CD25, CD26, and CD30 by allergen-specific T cells is intrinsically different in cow's milk allergy

scientific article published on 01 February 2002

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

scientific article

Characterization of T cell epitopes in alphas1-casein in cow's milk allergic, atopic and non-atopic children.

scientific article published on March 2006

Chemical modification of peanut conglutin reduces IgE reactivity but not T cell reactivity in peanut-allergic patients

scientific article published on 01 December 2014

Children with peanut allergy recognize predominantly Ara h2 and Ara h6, which remains stable over time.

scientific article published in August 2007

Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions

scientific article published on 01 May 2000

Comparing biologicals and small molecule drug therapies for chronic respiratory diseases

scientific article published on 08 January 2019

Components in soy allergy diagnostics: Gly m 2S albumin has the best diagnostic value in adults

scientific article published on 10 October 2013

Cyclosporin A reduces CD4(+)CD25(+) regulatory T-cell numbers in patients with atopic dermatitis.

scientific article published on 19 September 2009

Decreased neutrophil skin infiltration after UVB exposure in patients with polymorphous light eruption

scientific article

Degranulation of human basophils by picomolar concentrations of IL-3, IL-5, or granulocyte-macrophage colony-stimulating factor

scientific article published on 01 May 1998

Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized children.

scientific article published on February 2006

Diagnostic accuracy of specific IgE to components in diagnosing peanut allergy: a systematic review.

scientific article

Diagnostic phototesting in polymorphous light eruption: the optimal number of irradiations

scientific article published on 01 December 2005

Diagnostic tests based on human basophils: potentials, pitfalls and perspectives.

scientific article published on 11 July 2006

Differences in antigen-specific T-cell responses between infants with atopic dermatitis with and without cow's milk allergy: relevance of TH2 cytokines

scientific article published on 01 December 2000

Differential TLR-induced cytokine production by human mast cells is amplified by FcɛRI triggering.

scientific article published on April 2015

Differential activation of human basophils by anti-IgE and formyl-methionyl-leucyl-phenylalanine. Indications for protein kinase C-dependent and -independent activation pathways

scientific article published on 01 April 1991

Differential expression of cytokines in UV-B-exposed skin of patients with polymorphous light eruption: correlation with Langerhans cell migration and immunosuppression.

scientific article published in March 2004

Differential expression of genes involved in skin homing, proliferation, and apoptosis in CD4+ T cells of patients with atopic dermatitis.

scientific article

Does skin prick test reactivity to purified allergens correlate with clinical severity of peanut allergy?

scientific article published in January 2007

EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy

article

EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis.

scientific article

EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy.

scientific article published on 27 September 2017

EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders

scientific article published on 24 April 2015

EAACI Molecular Allergology User's Guide

scientific article

EAACI taskforce position paper: evidence for autoimmune urticaria and proposal for defining diagnostic criteria

scientific article

EASI p-EASI: Utilizing a combination of serum biomarkers offers an objective measurement tool for disease severity in atopic dermatitis patients

scientific article published on 16 August 2017

EASI p-EASI: predicting disease severity in atopic dermatitis patients treated with Cyclosporin A

scientific article published on 16 December 2018

Editorial: Basophil survival and immunomodulatory function are uniquely regulated by a novel MyD88-dependent pathway

scientific article published on 01 October 2009

Effect of birch pollen-specific immunotherapy on birch pollen-related hazelnut allergy

scientific article published on 08 October 2010

Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges.

scientific article

Efficient sorting of TNF-alpha to rodent mast cell granules is dependent on N-linked glycosylation

scientific article published in April 2006

Enzymatic treatment of whey proteins in cow's milk results in differential inhibition of IgE-mediated mast cell activation compared to T-cell activation

scientific article published on 21 June 2012

Enzymes involved in the conversion of arachidonic acid to eicosanoids in the skin of atopic dogs.

scientific article published in August 2010

Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha

scientific article published on 01 February 1998

Eosinophils isolated with two different methods show different characteristics of activation

scientific article published on 01 January 1995

Epicutaneous application of house dust mite induces thymic stromal lymphopoietin in nonlesional skin of patients with atopic dermatitis.

scientific article

Evaluation of T-cell activation in the duodenum of dogs with cutaneous food hypersensitivity

scientific article published on 01 April 2010

Expression of Fc receptors for IgG during acute and chronic cutaneous inflammation in atopic dermatitis

scientific article published on 01 June 2000

Expression of Fc(epsilon)RI on dendritic cell subsets in peripheral blood of patients with atopic dermatitis and allergic asthma

scientific article published on 01 July 2005

Function and expression of adhesion molecules on human basophils.

scientific article published on December 1994

Gene expression in CD4+ T-cells reflects heterogeneity in infant wheezing phenotypes

scientific article published on 09 July 2008

Gene expression profiles in childhood asthma: Differentiating between stable and acute asthma

article

Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine

scientific article

Granules of human eosinophilic leucocytes and their mobilization.

scientific article

Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement

scientific article published on 24 April 2020

Histamine-releasing activity in supernatants of mononuclear cells: contribution of monocyte chemotactic protein-1 activity compared with IgE-dependent activity

scientific article published on 01 November 1996

Historic overview of allergy research in the Netherlands

scientific article published on 18 October 2014

Identification of strong interleukin-10 inducing lactic acid bacteria which down-regulate T helper type 2 cytokines

scientific article published on 01 November 2005

IgE binding to a human profilin-containing fraction caused by contamination with yeast-derived material

scientific article published on 01 November 1995

Immune responses in dogs with cutaneous adverse food reactions.

scientific article published on June 2012

Influence of bronchial allergen challenge on histamine release by human basophils

scientific article published on 01 June 2000

Intracellular events in anti-IgE nonreleasing human basophils

scientific article published on 01 July 1992

Is randomization of breast-feeding feasible?

scientific article published on 01 June 2005

Legends of Allergy: Carla Bruijnzeel-Koomen

scientific article published on 05 November 2018

Lesional skin in atopic dogs shows a mixed Type-1 and Type-2 immune responsiveness

article

Localization of granule proteins in human eosinophil bone marrow progenitors

scientific article published on 01 October 1997

Low neonatal Toll-like receptor 4-mediated interleukin-10 production is associated with subsequent atopic dermatitis

article

Maintenance of tolerance to cow's milk in atopic individuals is characterized by high levels of specific immunoglobulin G4

scientific article published on 01 July 2007

Major hazelnut and peanut allergens are potent in basophil activation and cross-react at T-cell level

scientific article published on 02 July 2018

Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

scientific article published on 20 September 2011

Modulation of the atopy patch test: tacrolimus 0.1% compared with triamcinolone acetonide 0.1%

scientific article published on 01 May 2006

Monitoring human basophil activation via CD63 monoclonal antibody 435

scientific article published on 01 September 1991

Moving from peanut extract to peanut components: towards validation of component-resolved IgE tests.

scientific article

Narrowband ultraviolet B and medium-dose ultraviolet A1 are equally effective in the treatment of moderate to severe atopic dermatitis

scientific article published on 01 January 2009

No effect of anti-interleukin-5 therapy (mepolizumab) on the atopy patch test in atopic dermatitis patients

scientific article published on 23 August 2006

Non-Digestible Oligosaccharides Can Suppress Basophil Degranulation in Whole Blood of Peanut-Allergic Patients.

scientific article

Patients with anaphylaxis to pea can have peanut allergy caused by cross-reactive IgE to vicilin (Ara h 1)

scientific article published on 01 February 2003

Peanut allergen Ara h 3: isolation from peanuts and biochemical characterization.

scientific article published in November 2003

Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy

scientific article published on 30 January 2008

Potentiation of glucocorticoid-induced lysis in refractory and resistant leukemia cells by inhibitors of ADP-ribosylation

scientific article published on 01 January 1988

Probiotics for cow's milk allergy: classification after intervention

scientific article published on 01 February 2005

Probiotics for prevention of atopic disease?

scientific article published in August 2003

Probiotics have a different immunomodulatory potential in vitro versus ex vivo upon oral administration in children with food allergy

scientific article published on 09 February 2007

Pros and Cons of Clinical Basophil Testing (BAT).

scientific article

Purification and immunoglobulin E-binding properties of peanut allergen Ara h 6: evidence for cross-reactivity with Ara h 2.

scientific article

Reactivity to IgE-dependent histamine-releasing activity in asthma or rhinitis

scientific article published on 01 August 1996

Reactivity to IgE-dependent histamine-releasing factor is due to monomeric IgE

scientific article published on 01 July 2000

Recent developments in basophil research: do basophils initiate and perpetuate type 2 T-helper cell responses?.

scientific article published on 30 August 2012

Recognition of self-heat shock protein 60 by T cells from patients with atopic dermatitis ⬇️

scientific article published on August 7, 2012

Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils.

scientific article published in August 2003

Relevance of Ara h1, Ara h2 and Ara h3 in peanut-allergic patients, as determined by immunoglobulin E Western blotting, basophil-histamine release and intracutaneous testing: Ara h2 is the most important peanut allergen.

scientific article published in April 2004

Reply

scientific article published on 16 June 2017

Reply: To PMID 22939757.

scientific article published on 12 January 2013

Requirements for effective IgE cross-linking on mast cells and basophils.

scientific article published on July 2006

Research needs in allergy: an EAACI position paper, in collaboration with EFA.

scientific article published on 2 November 2012

Response of FcεRI-bearing leucocytes to omalizumab in chronic spontaneous urticaria

scientific article published on 07 February 2020

Role of human leucocyte antigen DQ in the presentation of T cell epitopes in the major cow's milk allergen alphas1-casein.

scientific article published on 16 January 2007

Salivary gland and peripheral blood T helper 1 and 2 cell activity in Sjögren's syndrome compared with non-Sjögren's sicca syndrome.

scientific article published on 7 April 2005

Sensitization to PR-10 proteins is indicative of distinctive sensitization patterns in adults with a suspected food allergy.

scientific article published on 23 November 2017

Serum biomarker profiles suggest that atopic dermatitis is a systemic disease

scientific article published in February 2018

Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell- attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis.

scientific article published in February 2004

Specific IgE to peanut 2S albumin Ara h 7 has a discriminative ability comparable to Ara h 2 and 6.

scientific article

Stimulus secretion coupling in human basophilic granulocytes.

scientific article published on June 1993

T cell responses to major peanut allergens in children with and without peanut allergy

scientific article published on 11 January 2010

TNF trafficking to human mast cell granules: mature chain-dependent endocytosis

scientific article

Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force Report.

scientific article

The IgE and basophil responses to Ara h 2 and Ara h 6 are good predictors of peanut allergy in children.

scientific article

The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation

scientific article published on 01 March 2000

The biological activity of a recombinantly expressed (His)(6)-tagged peanut allergen (rAra h 1) is unaffected by endotoxin removal.

scientific article published on 11 March 2008

The cAMP response element modulator (CREM) regulates TH2 mediated inflammation

scientific article published on 8 October 2015

The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease.

scientific article published on 21 July 2015

The diagnostic accuracy of specific IgE to Ara h 6 in adults is as good as Ara h 2.

scientific article published on 9 May 2014

The immune cell composition in Barrett's metaplastic tissue resembles that in normal duodenal tissue

scientific article

The immunological phenotype of rituximab-sensitive chronic graft-versus-host disease: a phase II study

scientific article

The in vitro diagnosis of drug allergy: status and perspectives.

scientific article published on 07 June 2011

The interleukin-10 inducing effect of transforming growth factor-beta on human naive CD4+ T cells from cord blood is restricted to the TH1 subset

scientific article published on 01 February 2007

Transforming growth factor-beta inhibits human antigen-specific CD4+ T cell proliferation without modulating the cytokine response

scientific article (publication date: December 2003)

Transmigration of human neutrophils across airway epithelial cell monolayers is preferentially in the physiologic basolateral-to-apical direction.

scientific article published on December 1996

Treatment for moderate to severe atopic dermatitis at alpine and moderate maritime climates differentially affect helper T cells and memory B cells in children.

scientific article published on 25 March 2018

Variability of IgE-dependent histamine-releasing activity in supernatants of human mononuclear cells

scientific article published on 01 January 1994

Which factors in raw cow's milk contribute to protection against allergies? ⬇️

scientific article published on August 30, 2012

n-3 Long-chain PUFA reduce allergy-related mediator release by human mast cells in vitro via inhibition of reactive oxygen species

scientific article

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