List of works by Laura Carrassa

A high-throughput screening of a chemical compound library in ovarian cancer stem cells

scientific article published on 23 January 2018

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736

scientific article published on 2 October 2015

Characterization of the 5'flanking region of the human Chk1 gene: identification of E2F1 functional sites

scientific article published on November 1, 2003

Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil.

scientific article

Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.

scientific article published on 13 September 2004

Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.

scientific article

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

scientific article published on 03 September 2019

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma

scientific article published on February 2015

Combining Ibrutinib with Chk1 Inhibitors Synergistically Targets Mantle Cell Lymphoma Cell Lines

scientific article published on 13 February 2018

DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas

scientific article published on 07 May 2019

DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy.

scientific article published on 19 September 2017

Inhibition of CHK1 and WEE1 as a new therapeutic approach in diffuse large B cell lymphomas with MYC deregulation

scientific article published on 26 December 2016

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer.

scientific article published on 19 February 2016

PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

scientific article

Role of Chk1 in the differentiation program of hematopoietic stem cells

scientific article published on 10 February 2010

Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2.

scientific article

The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents

scientific article published on 10 June 2019

The cytotoxic effect of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells is modulated by the expression level of MRP1 but not MDR1.

scientific article

Unique features of the mode of action of ET-743.

scientific article

Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways

scientific article published in May 2001

Unleashing Chk1 in cancer therapy.

scientific article published on July 2011

p38alpha as an inducer of aneuploidy in p53-/- tetraploid cells.

scientific article

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