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List of works by Thomas A Jepps

4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances Kv 7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

scientific article published on 20 November 2017

Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)

scientific article published on 23 April 2018

Contractile responses in intact and mucosa-denuded human ureter-a comparison with urinary bladder detrusor preparations

scientific article published on 28 April 2018

Contribution of Kv7 channels to basal coronary flow and active response to ischemia.

scientific article published on 30 September 2013

Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats

scientific article published on 29 December 2014

Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity.

scientific article published on 20 February 2014

Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular K currents and predisposes to ventricular arrhythmia

scientific article published on 05 October 2018

Downregulation of Kv7.4 channel activity in primary and secondary hypertension

scientific article published on 11 July 2011

Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-d-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

scientific article published on 05 September 2019

Expression and function of the K+ channel KCNQ genes in human arteries.

scientific article

Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.

scientific article

Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse

scientific article published on 01 January 2020

Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries

scientific article published on 18 December 2021

Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)

K(V)7 potassium channels: a new therapeutic target in smooth muscle disorders.

scientific article published on 12 December 2013

KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines

scientific article published on 30 September 2019

Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity

scientific article published on 7 October 2016

Kcne4 deletion sex dependently inhibits the RISK pathway response and exacerbates hepatic ischemia-reperfusion injury in mice

scientific article published on 13 February 2019

MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension

scientific article published on 7 July 2016

Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle.

scientific article published on 26 December 2017

Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats.

scientific article published on 23 January 2016

Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries ⬇️

scientific article published on June 1, 2012

Reduced KCNQ4-Encoded Voltage-Dependent Potassium Channel Activity Underlies Impaired β-Adrenoceptor–Mediated Relaxation of Renal Arteries in Hypertension ⬇️

scientific article published on February 21, 2012

TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension

scientific article published on 11 April 2019

Unravelling the complexities of vascular smooth muscle ion channels: Fine tuning of activity by ancillary subunits

scientific article

Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370

scientific article

pH-dependent inhibition of K₂P3.1 prolongs atrial refractoriness in whole hearts

scientific article published on 5 January 2016

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