List of works - Paul Fowler

5-Fluorouracil, colchicine, benzo[a]pyrene and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster V79 cells at Covance Laboratories, Harrogate, UK in support of OECD draft Test Guideline 487.

scientific article

A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity

scientific article published on 26 July 2016

A review of the genotoxicity of trimethylolpropane triacrylate (TMPTA)

scientific article published on 26 February 2018

Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?

scientific article published on 22 October 2017

An updated review of the genotoxicity of respirable crystalline silica.

scientific article

Cadmium chloride, benzo[a]pyrene and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Covance laboratories, Harrogate UK in support of OECD draft Test Guideline 487.

scientific article

Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487.

scientific article published on 10 March 2010

Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern.

scientific article published on 18 August 2010

Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

scientific article published on 25 February 2014

In vitro genotoxicity test approaches with better predictivity: Summary of an IWGT workshop ⬇️

scientific article published on April 5, 2011

Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement.

scientific article

Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. III: sensitivity of human cell types to known genotoxic agents

scientific article published on 13 March 2014

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type ⬇️

scientific article published on November 26, 2011

Stem cell-derived systems in toxicology assessment

scientific article

The utility of the in vitro micronucleus test for evaluating the genotoxicity of natural and manmade nano-scale fibres

scientific article

Where will genetic toxicology testing be in 30 years' time? Summary report of the 25th Industrial Genotoxicity Group Meeting, Royal Society of Medicine, London, November 9, 2011.

scientific article published on 11 December 2013

List of works by Paul Fowler

5-Fluorouracil, colchicine, benzo[a]pyrene and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster V79 cells at Covance Laboratories, Harrogate, UK in support of OECD draft Test Guideline 487.

A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity

A review of the genotoxicity of trimethylolpropane triacrylate (TMPTA)

Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?

An updated review of the genotoxicity of respirable crystalline silica.

Cadmium chloride, benzo[a]pyrene and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Covance laboratories, Harrogate UK in support of OECD draft Test Guideline 487.

Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487.

Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern.

Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

In vitro genotoxicity test approaches with better predictivity: Summary of an IWGT workshop ⬇️

Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement.

Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. III: sensitivity of human cell types to known genotoxic agents

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type ⬇️

Stem cell-derived systems in toxicology assessment

The utility of the in vitro micronucleus test for evaluating the genotoxicity of natural and manmade nano-scale fibres

Where will genetic toxicology testing be in 30 years' time? Summary report of the 25th Industrial Genotoxicity Group Meeting, Royal Society of Medicine, London, November 9, 2011.