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List of works by Peter Horak

A prospective, open label, randomized phase II trial of weekly docetaxel versus weekly vinorelbine as first line chemotherapy in patients with androgen independent prostate cancer

scientific article published on 01 June 2007

Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine

scientific article published on 31 July 2021

Circulating endothelial progenitor cells in castration resistant prostate cancer: a randomized, controlled, biomarker study

scientific article

Common death receptor 4 (DR4) polymorphisms do not predispose to ovarian cancer

scientific article published in May 2005

Community-driven development of a modified progression-free survival ratio for precision oncology

scientific article published on 13 November 2019

Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

scientific article published on 03 March 2020

Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer

scientific article published on June 2005

Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

scientific article published on 09 April 2019

Finding Options Beyond Standard of Care in Oncology: A Proposal for Workflows Utilizing Knowledge Databases

scientific article published on 01 August 2019

Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival

scientific article published in December 2005

Genomics of Immunotherapy-Associated Hyperprogressors-Letter.

scientific article published in October 2017

HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells

scientific article

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

scientific article

Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains

scientific article published on 26 September 2019

In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway.

scientific article published on 23 January 2007

Integrating next-generation sequencing into clinical oncology: strategies, promises and pitfalls

scientific article

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

scientific article published on 15 July 2019

Loss of the oligosaccharyl transferase subunit TUSC3 promotes proliferation and migration of ovarian cancer cells.

scientific article published on 12 February 2013

Metastatic adult pancreatoblastoma: Multimodal treatment and molecular characterization of a very rare disease

scientific article published on 29 February 2020

Methylation status of TUSC3 is a prognostic factor in ovarian cancer

scientific article published on 23 October 2012

NRG1 Fusions in KRAS Wild-type Pancreatic Cancer.

scientific article

Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis

scientific article

Patient expectations are better for immunotherapy than traditional chemotherapy for cancer

scientific article published on 19 August 2020

Personalized oncology

scientific article published on 5 September 2017

Perturbation of the tumor necrosis factor--related apoptosis-inducing ligand cascade in ovarian cancer: overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5.

scientific article published on December 2005

Precision oncology based on omics data: The NCT Heidelberg experience

scientific article

Promoter hypermethylation of GSTP1, AR, and 14-3-3sigma in serum of prostate cancer patients and its clinical relevance

scientific article published on 01 March 2007

Recurrence-free survival in prostate cancer is related to increased stromal TRAIL expression.

scientific article

Resistance to TRAIL-induced apoptosis in ovarian cancer cell lines is overcome by co-treatment with cytotoxic drugs.

scientific article published on July 2004

Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance.

scientific article published in April 2019

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Successful BRAF/MEK inhibition in a patient with BRAF V600E-mutated extrapancreatic acinar cell carcinoma

scientific article published on 25 August 2020

Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast

scientific article published on 20 November 2018

TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo

scientific article published on 17 January 2014

TUSC3: functional duality of a cancer gene.

scientific article published on 19 September 2017

Targeting rare and non-canonical driver variants in NSCLC – An uncharted clinical field

scientific article published on 21 February 2021

The landscape of chromothripsis across adult cancer types

scientific article published on 08 May 2020

The potential evasion of immune surveillance in mucosa associated lymphoid tissue lymphoma by DcR2-mediated up-regulation of nuclear factor-κB.

scientific article

The prognostic value of estrogen receptor beta and proline-, glutamic acid- and leucine-rich protein 1 (PELP1) expression in ovarian cancer.

scientific article

Tumor suppressor candidate 3 (TUSC3) prevents the epithelial-to-mesenchymal transition and inhibits tumor growth by modulating the endoplasmic reticulum stress response in ovarian cancer cells.

scientific article

Variant classification in precision oncology

scientific article published on 21 May 2019

hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer

scientific article published on 20 October 2011