List of works - Kate G Quinlan

1000 Norms Project: protocol of a cross-sectional study cataloging human variation

scientific article published on 22 January 2015

A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP

scientific article

A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site

scientific article published on 07 January 2019

ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling.

scientific article published on 16 September 2013

Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution

scientific article

An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance

scientific journal article

Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion

scientific article published on 17 December 2015

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling

scientific article published on 02 May 2011

Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells

scientific article

Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch

scientific article

Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain

scientific article published on 15 December 2015

Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.

scientific article

EoTHINophils: Eosinophils as key players in adipose tissue homeostasis

scientific article published on 12 March 2020

Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)

scientific article published on 10 June 2020

Evidence based selection of commonly used RT-qPCR reference genes for the analysis of mouse skeletal muscle

scientific article

Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans

scientific article

How does α-actinin-3 deficiency alter muscle function? Mechanistic insights into ACTN3, the 'gene for speed'.

scientific article

KLF1 drives the expression of fetal hemoglobin in British HPFH.

scientific article

Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).

scientific article

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

scientific article published on 24 September 2014

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

scientific journal article

Mechanisms directing the nuclear localization of the CtBP family proteins.

scientific article

Methylation of a CGATA element inhibits binding and regulation by GATA-1 ⬇️

scientific article published on 22 May 2020

NF1 is a critical regulator of muscle development and metabolism

scientific article

Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity

scientific article

Structural basis for human ZBTB7A action at the fetal globin promoter

scientific article published on 01 September 2021

The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins

scientific article (publication date: 2014)

The evolution of skeletal muscle performance: gene duplication and divergence of human sarcomeric alpha-actinins.

scientific article published on January 2010

The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y.

scientific article

α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization

scientific journal article

α-Actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle

article

List of works by Kate G Quinlan

1000 Norms Project: protocol of a cross-sectional study cataloging human variation

A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP

A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site

ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling.

Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution

An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance

Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling

Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells

Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch

Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain

Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.

EoTHINophils: Eosinophils as key players in adipose tissue homeostasis

Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)

Evidence based selection of commonly used RT-qPCR reference genes for the analysis of mouse skeletal muscle

Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans

How does α-actinin-3 deficiency alter muscle function? Mechanistic insights into ACTN3, the 'gene for speed'.

KLF1 drives the expression of fetal hemoglobin in British HPFH.

Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

Mechanisms directing the nuclear localization of the CtBP family proteins.

Methylation of a CGATA element inhibits binding and regulation by GATA-1 ⬇️

NF1 is a critical regulator of muscle development and metabolism

Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity

Structural basis for human ZBTB7A action at the fetal globin promoter

The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins

The evolution of skeletal muscle performance: gene duplication and divergence of human sarcomeric alpha-actinins.

The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y.

α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization

α-Actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle