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List of works by Suleiman Al-Sabah

A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor

scientific article published on 19 July 2019

A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.

scientific article published on 26 August 2003

Dual single-scission event analysis of constitutive transferrin receptor (TfR) endocytosis and ligand-triggered β2-adrenergic receptor (β2AR) or Mu-opioid receptor (MOR) endocytosis.

scientific article

Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization.

scientific article published on 25 November 2014

FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists

scientific article

Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket.

scientific article published on October 2010

Incretin response to a standard test meal in a rat model of sleeve gastrectomy with diet-induced obesity

scientific article published on 01 January 2014

Molecular Pharmacology of the Incretin Receptors.

scientific article published on 20 June 2015

Peptide binding at the GLP-1 receptor.

scientific article published on August 2007

Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor.

scientific article

Selectivity of peptide ligands for the human incretin receptors expressed in HEK-293 cells

scientific article published on 30 August 2014

The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively ⬇️

scientific article

The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists.

scientific article published in October 2003

The primary ligand-binding interaction at the GLP-1 receptor is via the putative helix of the peptide agonists.

scientific article published on February 2004

μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

scientific article

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