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List of works by Luc Friboulet

Acquired Resistance to Crizotinib from a Mutation in CD74 – ROS1

scientific article

BRAF in non-small cell lung cancer (NSCLC): Pickaxing another brick in the wall.

scientific article

Cabozantinib overcomes crizotinib resistance in ROS1 fusion-positive cancer

scientific article

Circulating tumor DNA genomics reveals potential mechanisms of resistance to BRAF-targeted therapies in BRAF-mutant metastatic non-small cell lung cancer patients

scientific article published on 28 August 2020

Clinicogenomic analysis of FGFR2-rearranged cholangiocarcinoma identifies correlates of response and mechanisms of resistance to pemigatinib

scientific article published on 20 November 2020

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade

scientific article published on 15 February 2018

ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform

scientific article

Facts and New Hopes on Selective FGFR Inhibitors in Solid Tumors

scientific article published on 04 October 2019

Feasibility and first reports of the MATCH-R repeated biopsy trial at Gustave Roussy

scientific article published on 08 September 2020

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer

scientific article published on 24 February 2021

Lorlatinib in ALK- and ROS1-positive NSCLC: the future has a start.

scientific article

Making the first move in EGFR-driven or ALK-driven NSCLC: first-generation or next-generation TKI?

scientific article published on 01 November 2018

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer

scientific article published on 18 July 2016

Molecular mechanisms of acquired resistance to third-generation EGFR-TKIs in EGFR T790M-mutant lung cancer.

scientific article published in January 2018

Oncogene addiction in non-small cell lung cancer: Focus on ROS1 inhibition

scientific article published on 12 March 2017

P-glycoprotein Mediates Ceritinib Resistance in Anaplastic Lymphoma Kinase-rearranged Non-small Cell Lung Cancer

scientific article published on 12 December 2015

PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models

scientific article published on 2 July 2015

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

scientific article

Primary Patient-Derived Cancer Cells and Their Potential for Personalized Cancer Patient Care

scientific article published in December 2017

Profile of entrectinib and its potential in the treatment of ROS1-positive NSCLC: evidence to date

scientific article published on 09 September 2019

Progression-Free and Overall Survival in ALK-Positive NSCLC Patients Treated with Sequential Crizotinib and Ceritinib

scientific article published on 27 February 2015

Recurrent overexpression of c-IAP2 in EBV-associated nasopharyngeal carcinomas: critical role in resistance to Toll-like receptor 3-mediated apoptosis

scientific article published on November 2008

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

scientific article

SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.

scientific article published on 5 March 2018

Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer

scientific article published on 14 March 2019

Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer

scientific article published on 12 April 2018

The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer

scientific article

Therapeutic management of ALK+ nonsmall cell lung cancer patients

scientific article published on 30 April 2015

Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib

scientific article