List of works - Asipu Sivaprasadarao

A beta-subclass phosphatidylinositol-specific phospholipase C from squid (Loligo forbesi) photoreceptors exhibiting a truncated C-terminus.

scientific article published on September 1995

A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.

scientific article published on 17 April 2013

A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris ⬇️

scientific article published on 26 February 2014

A method for determining transmembrane protein structure.

scientific article

Aberrant trafficking of transmembrane proteins in human disease

scientific article published on December 2003

Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor

scientific article

Adenosine receptor mRNA levels during postnatal renal maturation in the rat.

scientific article published in June 1998

Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A

scientific article

Changes in activation gating of IsK potassium currents brought about by mutations in the transmembrane sequence

scientific journal article

Conserved extracellular cysteine residues in the inwardly rectifying potassium channel Kir2.3 are required for function but not expression in the membrane

scientific article published in September 1999

Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density

scientific article

Depolarization induces intersubunit cross-linking in a S4 cysteine mutant of the Shaker potassium channel

scientific article published on 23 August 2002

Determinants of pH sensing in the two-pore domain K(+) channels TASK-1 and -2

scientific article (publication date: February 2003)

Effect of cysteine substitutions on the topology of the S4 segment of the Shaker potassium channel: implications for molecular models of gating

scientific article published in December 1999

Endocytosis of HERG is clathrin-independent and involves arf6.

scientific article

Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel

scientific article published in August 2003

Expression, characterization and engineered specificity of rat epididymal retinoic acid-binding protein ⬇️

scientific article published on August 15, 1998

Expression, purification, and evidence for the interaction of the two nucleotide-binding folds of the sulphonylurea receptor

scientific article

Functional properties of Kch, a prokaryotic homologue of eukaryotic potassium channels

scientific article published in September 2002

Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle. ⬇️

scientific article published on 23 January 2004

Generation of functional ion-channel tools by E3 targeting

scientific article published on 18 September 2005

High glucose-induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn2+-mediated mitochondrial fission. ⬇️

scientific article published in August 2017

Hyperinsulinemic Hypoglycemia in Beckwith-Wiedemann Syndrome due to Defects in the Function of Pancreatic β-Cell Adenosine Triphosphate-Sensitive Potassium Channels

scientific article published on 05 April 2005

Immunolocalisation of adenosine A(1) receptors in the rat kidney.

scientific article published in January 2001

Increased ATP-sensitive K+ channel expression during acute glucose deprivation

scientific article published on 4 August 2006

Inhibition of the K+ channel kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation

scientific article published in July 2000

Ionic signalling and mitochondrial dynamics ⬇️

scientific article

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels

scientific article

Lipocalin structure and function.

scientific article

Mapping the membrane-aqueous border for the voltage-sensing domain of a potassium channel

scientific article published on 19 October 2007

Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel.

scientific article published in November 1996

Membrane receptor for odour-binding proteins

scientific article published on July 1996

Modulation by protein kinase A of a cloned rat brain potassium channel expressed in Xenopus oocytes.

scientific article

Molecular cell biology of KATP channels: implications for neonatal diabetes

scientific article (publication date: August 2007)

Molecular mechanism of voltage sensor movements in a potassium channel.

scientific article published on 25 November 2004

Movement of the S4 segment in the hERG potassium channel during membrane depolarization

scientific article published on December 2009

Na(+)-induced inward rectification in the two-pore domain K(+) channel, TASK-2.

scientific article published on 24 August 2004

Novel mitochondrial complex I inhibitors restore glucose-handling abilities of high-fat fed mice.

scientific article published on 12 January 2016

Reciprocal regulation of actin cytoskeleton remodelling and cell migration by Ca2+ and Zn2+: role of TRPM2 channels ⬇️

scientific journal article

Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II.

scientific article published on 6 December 2012

Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.

scientific article published in March 1997

Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms

scientific article

Role of hydrophobic and ionic forces in the movement of S4 of the Shaker potassium channel

scientific article published on 13 August 2012

Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism

scientific article published on 8 April 2009

Selectivity and interactions of Ba2+ and Cs+ with wild-type and mutant TASK1 K+ channels expressed in Xenopus oocytes

scientific article published on 20 December 2004

Synthetic ion channels via self-assembly: a route for embedding porous polyoxometalate nanocapsules in lipid bilayer membranes

scientific article

TRPC channel activation by extracellular thioredoxin

scientific article

TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia ⬇️

scientific article

TRPM2 channels in mitochondrial dynamics and cancer ⬇️

scientific article

TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death

scientific article

TRPM2-mediated rise in mitochondrial Zn(2+) promotes palmitate-induced mitochondrial fission and pancreatic β-cell death in rodents ⬇️

scientific article

TRPM2: Shredding the mitochondrial network ⬇️

scientific article

The structure of β-lactoglobulin and its similarity to plasma retinol-binding protein

scientific article published in Nature

The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane receptor

scientific article

The transfer of transthyretin and receptor-binding properties from the plasma retinol-binding protein to the epididymal retinoic acid-binding protein

scientific article

Trafficking of ATP-sensitive potassium channels in health and disease

scientific article published on November 2007

Translocon closure to Ca2+ leak in proliferating vascular smooth muscle cells

scientific article published on 13 February 2009

Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore

scientific article published on 20 May 2011

pH sensing in the two-pore domain K+ channel, TASK2.

scientific article

List of works by Asipu Sivaprasadarao

A beta-subclass phosphatidylinositol-specific phospholipase C from squid (Loligo forbesi) photoreceptors exhibiting a truncated C-terminus.

A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.

A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris ⬇️

A method for determining transmembrane protein structure.

Aberrant trafficking of transmembrane proteins in human disease

Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor

Adenosine receptor mRNA levels during postnatal renal maturation in the rat.

Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A

Changes in activation gating of IsK potassium currents brought about by mutations in the transmembrane sequence

Conserved extracellular cysteine residues in the inwardly rectifying potassium channel Kir2.3 are required for function but not expression in the membrane

Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density

Depolarization induces intersubunit cross-linking in a S4 cysteine mutant of the Shaker potassium channel

Determinants of pH sensing in the two-pore domain K(+) channels TASK-1 and -2

Effect of cysteine substitutions on the topology of the S4 segment of the Shaker potassium channel: implications for molecular models of gating

Endocytosis of HERG is clathrin-independent and involves arf6.

Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel

Expression, characterization and engineered specificity of rat epididymal retinoic acid-binding protein ⬇️

Expression, purification, and evidence for the interaction of the two nucleotide-binding folds of the sulphonylurea receptor

Functional properties of Kch, a prokaryotic homologue of eukaryotic potassium channels

Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle. ⬇️

Generation of functional ion-channel tools by E3 targeting

High glucose-induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn2+-mediated mitochondrial fission. ⬇️

Hyperinsulinemic Hypoglycemia in Beckwith-Wiedemann Syndrome due to Defects in the Function of Pancreatic β-Cell Adenosine Triphosphate-Sensitive Potassium Channels

Immunolocalisation of adenosine A(1) receptors in the rat kidney.

Increased ATP-sensitive K+ channel expression during acute glucose deprivation

Inhibition of the K+ channel kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation

Ionic signalling and mitochondrial dynamics ⬇️

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels

Lipocalin structure and function.

Mapping the membrane-aqueous border for the voltage-sensing domain of a potassium channel

Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel.

Membrane receptor for odour-binding proteins

Modulation by protein kinase A of a cloned rat brain potassium channel expressed in Xenopus oocytes.

Molecular cell biology of KATP channels: implications for neonatal diabetes

Molecular mechanism of voltage sensor movements in a potassium channel.

Movement of the S4 segment in the hERG potassium channel during membrane depolarization

Na(+)-induced inward rectification in the two-pore domain K(+) channel, TASK-2.

Novel mitochondrial complex I inhibitors restore glucose-handling abilities of high-fat fed mice.

Reciprocal regulation of actin cytoskeleton remodelling and cell migration by Ca2+ and Zn2+: role of TRPM2 channels ⬇️

Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II.

Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.

Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms

Role of hydrophobic and ionic forces in the movement of S4 of the Shaker potassium channel

Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism

Selectivity and interactions of Ba2+ and Cs+ with wild-type and mutant TASK1 K+ channels expressed in Xenopus oocytes

Synthetic ion channels via self-assembly: a route for embedding porous polyoxometalate nanocapsules in lipid bilayer membranes

TRPC channel activation by extracellular thioredoxin

TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia ⬇️

TRPM2 channels in mitochondrial dynamics and cancer ⬇️

TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death

TRPM2-mediated rise in mitochondrial Zn(2+) promotes palmitate-induced mitochondrial fission and pancreatic β-cell death in rodents ⬇️

TRPM2: Shredding the mitochondrial network ⬇️

The structure of β-lactoglobulin and its similarity to plasma retinol-binding protein

The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane receptor

The transfer of transthyretin and receptor-binding properties from the plasma retinol-binding protein to the epididymal retinoic acid-binding protein

Trafficking of ATP-sensitive potassium channels in health and disease

Translocon closure to Ca2+ leak in proliferating vascular smooth muscle cells

Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore

pH sensing in the two-pore domain K+ channel, TASK2.