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List of works by Zakaria Eltahir

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer

scientific article

Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett's oesophagus.

scientific article

Deoxycholic acid at neutral and acid pH, is genotoxic to oesophageal cells through the induction of ROS: The potential role of anti-oxidants in Barrett's oesophagus

scientific article published on 11 August 2006

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study.

scientific article published on 08 August 2017

Inducible nitric oxide synthase (iNOS) and nitric oxide (NO) are important mediators of reflux-induced cell signalling in esophageal cells.

scientific article

Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice

scientific article published in January 2018

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.

scientific article

MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma

scientific article published on 4 November 2017

Mismatch Repair Deficiency, Microsatellite Instability, and Survival: An Exploratory Analysis of the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) Trial.

scientific article

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

scientific article

Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.

scientific article

Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients.

scientific article published on 05 July 2016

The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF-kappaB activation in oesophageal cells, with a mechanism of action involving ROS.

scientific article

The genomic landscape of oesophagogastric junctional adenocarcinoma

scientific article

The role of secondary bile acids in neoplastic development in the oesophagus.

scientific article published on April 2010

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