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List of works by Christele Desbois-Mouthon

Deletion of Asn281 in the alpha-subunit of the human insulin receptor causes constitutive activation of the receptor and insulin desensitization

scientific article published on 01 February 1996

Detection of sequence variations in the human insulin-receptor gene by parallel denaturing gradient gel electrophoresis.

scientific article

Dominant transmission of insulin resistance in a type A family resulting from a heterozygous nonsense mutation in the insulin receptor gene and associated with decreased mRNA level and insulin binding sites

scientific article published on 01 November 1997

Dysregulation of glycogen synthase kinase-3beta signaling in hepatocellular carcinoma cells.

scientific article published on December 2002

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells.

scientific article published on 10 March 2012

Erratum to: Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin.

scientific article published on 28 September 2016

GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis.

scientific article published on July 2005

Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma

scientific article published on 16 December 2016

Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor.

scientific article published on 25 October 2013

Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout

scientific article published on 16 February 2006

Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin.

scientific article

Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma.

scientific article published on 29 June 2015

IGF2/IR/IGF1R pathway in tumor cells and myofibroblasts mediates resistance to EGFR inhibition in cholangiocarcinoma.

scientific article

Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib

scientific article published on 01 December 2006

Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.

scientific article published on 14 September 2010

Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2.

scientific article

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

scientific article published on 01 January 2001

Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase.

scientific article published on October 1999

Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors

scientific article published on 01 February 1998

Insulin receptor isoform A favors tumor progression in human hepatocellular carcinoma by increasing stem/progenitor cell features

scientific article published on 06 March 2019

Insulin-mediated cell proliferation and survival involve inhibition of c-Jun N-terminal kinases through a phosphatidylinositol 3-kinase- and mitogen-activated protein kinase phosphatase-1-dependent pathway

scientific article published on 01 March 2000

Involvement of small ArfGAP1 (SMAP1), a novel Arf6-specific GTPase-activating protein, in microsatellite instability oncogenesis

scientific article published on June 10, 2013

Late-onset lipoatrophic diabetes. Phenotypic and genotypic familial studies and effect of treatment with metformin and lispro insulin analog

scientific article published on 01 August 1999

Lipoatrophic diabetes: genetic exclusion of the insulin receptor gene

scientific article published on 01 January 1995

Loss of EBP50 stimulates EGFR activity to induce EMT phenotypic features in biliary cancer cells.

scientific article

Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma.

scientific article published on September 2017

Major circadian variations of glucose homeostasis in a patient with Rabson-Mendenhall syndrome and primary insulin resistance due to a mutation (Cys284-->Tyr) in the insulin receptor alpha-subunit.

scientific article published in July 1997

Major insulin resistance syndromes: clinical and physiopathological aspects

scientific article (publication date: 2001)

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to hydrogen peroxide-induced oxidative stress in human hepatobiliary cancer cells.

scientific article

Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors

scientific journal article

Molecular analysis of the insulin receptor gene for prenatal diagnosis of leprechaunism in two families

scientific article published on 01 July 1997

Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma.

scientific article

Potentials of CRISPR in liver research and therapy

scientific article published on 05 June 2018

Regulation of the EGFR/ErbB signalling by clathrin in response to various ligands in hepatocellular carcinoma cell lines

scientific article published on 09 June 2020

Severe resistance to insulin and insulin-like growth factor-I in cells from a patient with leprechaunism as a result of two mutations in the tyrosine kinase domain of the insulin receptor.

scientific article published on December 1996

Somatostatin receptors in resected hepatocellular carcinoma: status and correlation with markers of poor prognosis

scientific article published on 8 July 2016

Targeting STAT3 in hepatocellular carcinoma: sorafenib again….

scientific article

The beta secretase BACE1 regulates the expression of insulin receptor in the liver

scientific article published on 3 April 2018

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

scientific article published on 11 December 2015

[Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma]

scientific article published on 01 October 2006