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List of works by Madelon M Maurice

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells

scientific article published in Nature Communications

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network

scientific article

CD28 co-stimulation is intact and contributes to prolongedex vivo survival of hyporesponsive synovial fluid T cells in rheumatoid arthritis

scientific article published on May 1, 1998

Canonical Wnt signaling negatively modulates regulatory T cell function.

scientific article published on 15 August 2013

Characterization of the hyporesponsiveness of synovial T-cells in rheumatoid arthritis: Role of chronic oxidative stress

scientific article published on 01 April 1999

Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules

scientific article

Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded

scientific article

DEP domains: structurally similar but functionally different

scientific article published on 16 April 2014

Defective TCR-mediated signaling in synovial T cells in rheumatoid arthritis

scientific article published on 01 September 1997

Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp

scientific article published on 3 October 2012

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling

scientific article

Epstein-Barr virus DNA in Reed-Sternberg cells of Hodgkin's disease is frequently associated with CR2 (EBV receptor) expression

scientific article published on July 1, 1992

Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis

scientific article published on 01 November 1999

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

scientific article

Heterogeneity of the circulating human CD4+ T cell population. Further evidence that the CD4+CD45RA-CD27- T cell subset contains specialized primed T cells.

scientific article published in January 1995

How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

scientific article published on 18 March 2002

Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma

scientific article published on 23 March 2007

In vivo role of lipid adducts on Wingless

scientific article published on 22 April 2008

Investigations of dynamic amyloid-like structures of the Wnt signalling pathway by solid-state NMR

scientific article published on 01 April 2018

Joint-derived T cells in rheumatoid arthritis proliferate to antigens present in autologous synovial fluid

scientific article published on 01 January 1995

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations

scientific article

Loss of CYLD expression unleashes Wnt signaling in multiple myeloma and is associated with aggressive disease.

scientific article published on 24 October 2016

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

scientific article

Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl

scientific article

Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia.

scientific article

Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?

scientific article

Molecular regulation and pharmacological targeting of the β-catenin destruction complex

scientific article

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex

scientific article

Mutations and mechanisms of WNT pathway tumour suppressors in cancer

scientific article published on 23 October 2020

Organoid-based modeling of intestinal development, regeneration, and repair

scientific article published on 18 November 2020

Proteome changes induced by knock-down of the deubiquitylating enzyme HAUSP/USP7.

scientific article published on 10 October 2007

Publisher Correction: Mutations and mechanisms of WNT pathway tumour suppressors in cancer

scientific article published on 04 November 2020

RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer

scientific article published on 10 August 2020

Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts

scientific article

Redox Balance Alterations and Hyporesponsiveness of Synovial T Cells in Rheumatoid Arthritis.

scientific article published on 15 November 1999

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

scientific article published in February 2018

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

scientific article

Stochastic machines as a colocalization mechanism for scaffold protein function

scientific article

Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins

scientific article published on 6 December 2017

TMEM59 potentiates Wnt signaling by promoting signalosome formation.

scientific article

Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer

article by Maureen Spit et al published 12 September 2018 in Open Biology

The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

scientific article published in November 2002

The various roles of ubiquitin in Wnt pathway regulation.

scientific article published on 25 September 2010

Three-dimensional analysis of single molecule FISH in human colon organoids

scientific article published on 09 August 2019

Thymic Selection and Peripheral Activation of CD8 T Cells by the Same Class I MHC/Peptide Complex

scientific article published on 01 January 2004

Treatment with monoclonal anti-tumor necrosis factor alpha antibody results in an accumulation of Th1 CD4+ T cells in the peripheral blood of patients with rheumatoid arthritis

scientific article published in October 1999

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

scientific article published on 30 August 2012

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

scientific article published on 11 May 2015

Variants in members of the cadherin-catenin complex, CDH1 and CTNND1, cause blepharocheilodontic syndrome.

scientific article

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

scientific article published on 10 February 2016

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

scientific article

Wnt Signaling Directs Neuronal Polarity and Axonal Growth

scientific article published on 02 March 2019

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex

scientific article

Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes

scientific article

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

scientific article published on 12 March 2012