List of works by Tom G Richardson

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

scientific article published on 10 January 2020

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

scientific article published on 01 June 2019

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

scientific article published on 25 February 2022

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

scientific article published on 24 August 2016

Conditioning on a Collider May Induce Spurious Associations: Do the Results of Gale et al. (2017) Support a Health-Protective Effect of Neuroticism in Population Subgroups?

article

Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

scientific article published on 21 May 2021

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis

scientific article published on 01 November 2021

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

scientific article published on 03 February 2021

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

scientific article published on 23 March 2020

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

scientific article

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report

scientific article published in March 2022

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

scientific article published on 24 June 2019

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

scientific article published on 08 January 2021

Influence of adiposity-related genetic markers in a population of saudi arabians where other variables influencing obesity may be reduced

scientific article

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

scientific article published on 01 October 2019

Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes

scientific article published on 05 November 2021

Investigating causal pathways between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.: Supplemental material

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

scientific article published on 16 November 2019

Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

scientific article published in 2021

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

scientific article published in October 2017

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

scientific article published in August 2018

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

scientific article published on 07 September 2020

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

scientific article published on 20 February 2020

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study

scientific article published on 06 May 2020

Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications

scientific article

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