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List of works by Jeroen L Pennings

A Combination of Factors Related to Smoking Behavior, Attractive Product Characteristics, and Socio-Cognitive Factors are Important to Distinguish a Dual User from an Exclusive E-Cigarette User

scientific article published on 30 October 2019

A Review of Toxicogenomic Approaches in Developmental Toxicology

scientific article published on January 1, 2012

A bead-based multiplexed immunoassay to evaluate breast cancer biomarkers for early detection in pre-diagnostic serum.

scientific article published on 22 October 2012

A next-generation sequencing based method for determining genetic stability in Clostridium tetani vaccine strains

scientific article published on 11 February 2020

A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction.

scientific article published on 19 January 2017

A statistical approach towards the derivation of predictive gene sets for potency ranking of chemicals in the mouse embryonic stem cell test.

scientific article published on 27 January 2014

Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome.

scientific article published on March 2016

Activation of Human Monocytes by Colloidal Aluminum Salts

scientific article published on 23 August 2019

Adaptation of methane formation and enzyme contents during growth of Methanobacterium thermoautotrophicum (strain deltaH) in a fed-batch fermentor

scientific article published on 01 April 2000

Adipose gene expression patterns of weight gain suggest counteracting steroid hormone synthesis

scientific article published in June 2005

Adipose gene expression response of lean and obese mice to short-term dietary restriction.

scientific article published in June 2006

Aldehyde and VOC yields in commercial cigarette mainstream smoke are mutually related and depend on the sugar and humectant content in tobacco

scientific article published on 04 November 2019

Aluminum Hydroxide And Aluminum Phosphate Adjuvants Elicit A Different Innate Immune Response

An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome

scientific article published on 02 September 2016

An adverse outcome pathway framework for neural tube and axial defects mediated by modulation of retinoic acid homeostasis

scientific article

Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome

scientific article published on 25 July 2014

Antibody Specificity Following a Recent Bordetella pertussis Infection in Adolescence Is Correlated With the Pertussis Vaccine Received in Childhood

scientific article published on 17 June 2019

Application of the comparison approach to open TG-GATEs: A useful toxicogenomics tool for detecting modes of action in chemical risk assessment

scientific article published on 08 August 2018

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

scientific article published on 21 October 2010

Bead-based multiplexed immunoassays to identify new biomarkers in maternal serum to improve first trimester Down syndrome screening.

scientific article

Biomarker discovery using a comparative omics approach in a mouse model developing heterogeneous mammary cancer subtypes.

scientific article published on July 2012

Biomarkers for circadian rhythm disruption independent of time of day

scientific article

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.

scientific article published on December 2016

Cellular levels of factor 390 and methanogenic enzymes during growth of Methanobacterium thermoautotrophicum deltaH.

scientific article

Characteristic Human Individual Puffing Profiles Can Generate More TNCO than ISO and Health Canada Regimes on Smoking Machine When the Same Brand Is Smoked

scientific article published on 06 May 2020

Chronic sleep restriction in the rotenone Parkinson's disease model in rats reveals peripheral early-phase biomarkers

scientific article published in Scientific Reports

Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice.

scientific article published on July 2015

Cigarette Filter Ventilation and Smoking Protocol Influence Aldehyde Smoke Yields.

scientific article published on 17 May 2018

Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices

scientific article published on 16 February 2016

Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection.

scientific article

Comparison of MeHg-induced toxicogenomic responses across in vivo and in vitro models used in developmental toxicology.

scientific article published on June 2011

Comparison of different blood collection, sample matrix, and immunoassay methods in a prenatal screening setting

scientific article

Comparison of gene expression regulation in mouse- and human embryonic stem cell assays during neural differentiation and in response to valproic acid exposure.

scientific article published on 11 June 2015

Comparison of the molecular topologies of stress-activated transcription factors HSF1, AP-1, NRF2, and NF-κB in their induction kinetics of HMOX1.

scientific article published on 6 September 2014

Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests.

scientific article published on 13 December 2012

Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).

scientific article published on 23 May 2012

Comprehensive overview of common e-liquid ingredients and how they can be used to predict an e-liquid's flavour category

scientific article published on 10 February 2020

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures

scientific article published on December 28, 2010

Corrigendum to 'Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis' [Toxicol. Appl. Pharmacol., 322 (2017) 15-26]

scientific article published on 03 July 2018

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

scientific article published on July 3, 2013

Degradable dU-based DNA template as a standard in real-time PCR quantitation.

scientific article

Delayed expression of apoptotic and cell-cycle control genes in carcinogen-exposed bladders of mice lacking p53.S389 phosphorylation

scientific article published on 21 February 2007

Deregulation of Cancer-Related Pathways in Primary Hepatocytes Derived from DNA Repair-Deficient Xpa−/−p53+/− Mice upon Exposure to Benzo[a]pyrene

scientific article published on June 29, 2011

Differential effects of fluoxetine and venlafaxine in the neural embryonic stem cell test (ESTn) revealed by a cell lineage map

scientific article published on 05 October 2019

Discovery of novel serum biomarkers for prenatal Down syndrome screening by integrative data mining.

scientific article

Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test

scientific article published on December 30, 2010

Diurnal Variation of Hormonal and Lipid Biomarkers in a Molecular Epidemiology-Like Setting

scientific article published on 18 August 2015

Dose response analysis of monophthalates in the murine embryonic stem cell test assessed by cardiomyocyte differentiation and gene expression.

scientific article published on 17 July 2012

Dose-response analysis of phthalate effects on gene expression in rat whole embryo culture.

scientific article published on 24 July 2012

Down syndrome screening: imagining the screening test of the future.

scientific article published on May 2010

Dried blood spot measurement of pregnancy-associated plasma protein A (PAPP-A) and free β-subunit of human chorionic gonadotropin (β-hCG) from a low-resource setting

scientific article

Dysregulation of serum gamma interferon levels in vascular chronic Q Fever patients provides insights into disease pathogenesis.

scientific article published on 29 April 2015

Effects of pooling RNA from samples treated with different compounds for determining class specific biomarkers and processes in toxicogenomics

scientific article published on May 19, 2011

Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.

scientific article published on 23 September 2010

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures

scientific article published on October 8, 2010

Evaluation of immunomodulation by Lactobacillus casei Shirota: immune function, autoimmunity and gene expression

scientific article published on 26 July 2006

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling.

scientific article published on 6 April 2013

Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay.

scientific article published on 15 May 2015

Gene expression changes in the mesenteric lymph nodes of rats after oral peanut extract exposure.

scientific article published on October 2008

Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans.

scientific article published on 24 July 2014

Gene expression profiles induced by Salmonella infection in resistant and susceptible mice.

scientific article published on 20 January 2011

Gene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening.

scientific article

Gene set assembly for quantitative prediction of developmental toxicity in the embryonic stem cell test.

scientific article

Genotoxic exposure: novel cause of selection for a functional ΔN-p53 isoform

scientific article published on 13 December 2010

Host transcription profiles upon primary respiratory syncytial virus infection

scientific article published on 21 March 2007

Identification by gene coregulation mapping of novel genes involved in embryonic stem cell differentiation.

scientific article published on 18 August 2010

Identification of a common gene expression response in different lung inflammatory diseases in rodents and macaques.

scientific article

Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells.

scientific article published on 18 September 2013

Identification of breast cancer biomarkers in transgenic mouse models: A proteomics approach

scientific article published on 24 March 2010

Identification of flavour additives in tobacco products to develop a flavour library.

scientific article

Identification of interleukin‐1 beta, but no other inflammatory proteins, as an early onset pre‐eclampsia biomarker in first trimester serum by bead‐based multiplexed immunoassays

scientific article published on August 31, 2013

Immunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune Cells

scientific article

Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity.

scientific article published on 2 June 2015

In vitro effects of aldehydes present in tobacco smoke on gene expression in human lung alveolar epithelial cells.

scientific article published on 14 February 2013

In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics

scientific article published on 05 May 2007

Integrative data mining to identify novel candidate serum biomarkers for pre-eclampsia screening.

scientific article

Isolation and Characterization of Methanobacterium thermoautotrophicum ΔH Mutants Unable To Grow under Hydrogen-Deprived Conditions

scientific article published on May 1, 1998

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

scientific article published on 20 June 2010

Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome.

scientific article

Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A.

scientific article published on 17 October 2014

Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling

scientific article published on 9 May 2007

Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity

scientific article published on 2 March 2016

Medium-reductant directed expression of methyl coenzyme M reductase isoenzymes in Methanobacterium thermoautotrophicum (strain deltaH)

scientific article published on 01 June 1997

Meta-Analysis of Pulmonary Transcriptomes from Differently Primed Mice Identifies Molecular Signatures to Differentiate Immune Responses following Bordetella pertussis Challenge.

scientific article published on 24 January 2017

Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers

scientific article published on 22 February 2017

Metabolomics profiling for identification of novel potential markers in early prediction of preeclampsia.

scientific article

Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination

scientific article published on 7 February 2018

Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

scientific article published on 20 September 2017

Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection.

scientific article

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

scientific article published on 26 April 2010

Nearly 20 000 e-liquids and 250 unique flavour descriptions: an overview of the Dutch market based on information from manufacturers

scientific article published on 04 November 2019

Neural crest related gene transcript regulation by valproic acid analogues in the cardiac embryonic stem cell test

scientific article published on 21 August 2019

Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness.

scientific article published on 6 January 2018

Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.

scientific article

Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status

scientific article published on 09 November 2006

Predictive performance of a seven-plex antibody array in prenatal screening for Down Syndrome.

scientific article published on 23 April 2015

Preoperative fasting protects against renal ischemia-reperfusion injury in aged and overweight mice.

scientific article

Programmed Effects in Neurobehavior and Antioxidative Physiology in Zebrafish Embryonically Exposed to Cadmium: Observations and Hypothesized Adverse Outcome Pathway Framework.

scientific article

Protein expression profiling of mouse thymoma cells upon exposure to the trichothecene deoxynivalenol (DON): Implications for its mechanism of action

scientific article published on July 1, 2010

Proteome Analysis Is a Valuable Tool to Monitor Antigen Expression during Upstream Processing of Whole-Cell Pertussis Vaccines.

scientific article published on 15 December 2016

Proteome profiling of mouse embryonic stem cells to define markers for cell differentiation and embryotoxicity.

scientific article published on 27 May 2010

Proteomic analysis of chicken bone marrow-derived dendritic cells in response to an inactivated IBV + NDV poultry vaccine

scientific article published on 16 June 2021

Proteomics and Down syndrome screening: a validation study

scientific article published on 01 November 2010

Quantitative performance of antibody array technology in a prenatal screening setting

scientific article published on October 28, 2011

Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines.

scientific article published on 25 February 2013

Recommendations of the VAC2VAC workshop on the design of multi-centre validation studies.

scientific article published on 25 January 2018

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

scientific article

Sensory Evaluation of E-Liquid Flavors by Smelling and Vaping Yields Similar Results

scientific article published on 01 April 2020

Significant Effects of Maternal Diet During Pregnancy on the Murine Fetal Brain Transcriptome and Offspring Behavior

scientific article published on 17 December 2019

Slow accumulation of mutations in Xpc-/- mice upon induction of oxidative stress.

scientific article

Systemic Signature of the Lung Response to Respiratory Syncytial Virus Infection

scientific article published on June 24, 2011

The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts.

scientific article

The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome.

scientific article

The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

scientific article published on 15 March 2019

Time-Response Evaluation by Transcriptomics of Methylmercury Effects on Neural Differentiation of Murine Embryonic Stem Cells

scientific article published on May 25, 2011

Toxicogenomics in the assessment of immunotoxicity.

scientific article published on January 2007

Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats.

scientific article published in May 2004

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.

scientific article published on 27 April 2016

Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).

scientific article

Transcriptomics analysis of retinoic acid embryotoxicity in rat postimplantation whole embryo culture.

scientific article published on 19 May 2010

Transcriptomics in lung tissue upon respiratory syncytial virus infection reveals aging as important modulator of immune activation and matrix maintenance

scientific article published in Scientific Reports

Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice

scientific article published on 23 January 2021

Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks

scientific article published on August 10, 2012

Vaccine antigens modulate the innate response of monocytes to Al(OH)3.

scientific article published on 29 May 2018

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach

scientific article published on 25 June 2016

Valproic acid-induced gene expression responses in rat whole embryo culture and comparison across in vitro developmental and non-developmental models.

scientific article published on 28 June 2013

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

scientific article published on 19 December 2015