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List of works by Takaya Moriyama

A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

scientific article published on 12 February 2016

Combination of common and novel rare NUDT15 variants improves predictive sensitivity of thiopurine-induced leukopenia in children with acute lymphoblastic leukemia.

scientific article published on 8 March 2018

Familial acute lymphoblastic leukemia

scientific article

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study

scientific article

Inherited genetic variation in childhood acute lymphoblastic leukemia

scientific article published on 21 May 2015

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

scientific journal article

Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and anti-leukemic efficacy.

scientific article published on 23 March 2018

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

scientific article

The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia

scientific article published on 25 April 2017

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

scientific article published on 30 November 2016

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